Tiberiu Holban

ORCID: 0000-0003-0923-3129
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • HIV/AIDS Research and Interventions
  • Antibiotic Use and Resistance
  • HIV, Drug Use, Sexual Risk
  • Bacillus and Francisella bacterial research
  • Syphilis Diagnosis and Treatment
  • HIV Research and Treatment
  • Hepatitis B Virus Studies
  • Fungal Infections and Studies
  • Antifungal resistance and susceptibility
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Pneumonia and Respiratory Infections
  • Yersinia bacterium, plague, ectoparasites research
  • Microbial Metabolism and Applications
  • Diphtheria, Corynebacterium, and Tetanus
  • HIV/AIDS drug development and treatment
  • COVID-19 Clinical Research Studies
  • Poxvirus research and outbreaks
  • HIV-related health complications and treatments
  • Antibiotic Resistance in Bacteria
  • Leptospirosis research and findings
  • Liver Disease and Transplantation
  • Mycobacterium research and diagnosis
  • Viral Infections and Outbreaks Research

Clinical Emergency Hospital Bucharest
2024

Nicolae Testemițanu State University of Medicine and Pharmacy
2013-2024

National Institute of Research and Development for Biological Sciences
2016

C. auris is a newly emerging yeast, raising public health concerns due to its outbreak potential, lack of protocols for decontamination and isolation patients or contacts, increased resistance common antifungals associated high mortality. This research aimed describe the challenges related identifying outbreak, limiting further contamination, treating affected individuals. We retrospectively analysed all cases detected between October 2022 August 2023, but our investigation focused on...

10.20944/preprints202403.0911.v1 preprint EN 2024-03-15

Objectives Pre‐exposure prophylaxis (PrEP) for HIV infection is an important intervention control of the epidemic. The incidence increasing in countries Central and Eastern Europe (CEE). Therefore, we investigated change PrEP use CEE over time. Methods Euroguidelines (ECEE) Network Group was initiated February 2016 to compare standards care viral hepatitis infections CEE. Data on access were collected from 23 through online surveys May–June 2017 (76 respondents) November 2018–May 2019 (28...

10.1111/hiv.12960 article EN HIV Medicine 2020-10-05

Survey was conducted to assess state of viral hepatitis care in Central and Eastern Europe (CEE).Representatives 16 CEE countries completed on-line survey April-May 2017 that collected information on basic epidemiology availability key services for HCV HBV infections. Sources provided ranged from national surveillance data expert opinion.The burden varied between countries, ranging 6,500 2 million 10,000 3 HBV. Access routine RNA testing genotyping reported by 11 9 respectively. resistance...

10.21101/cejph.a5486 article EN Central European Journal of Public Health 2019-09-30

Candida auris is a newly emerging yeast, which raising public health concerns due to its outbreak potential, lack of protocols for decontamination and isolation patients or contacts, increased resistance common antifungals, associated high mortality. This research aimed describe the challenges related identifying outbreak, limiting further contamination, treating affected individuals. We retrospectively analyzed all cases C. detected between October 2022 August 2023, but our investigation...

10.3390/antibiotics13040325 article EN cc-by Antibiotics 2024-04-03

With the increasing burden of carbapenem-resistant Klebsiella pneumoniae (CR-Kp), including high rates healthcare-associated infections, treatment failure, and mortality, a good therapeutic strategy for attacking this multi-resistant pathogen is one main goals in current medical practice necessitates use novel antibiotics or new drug combinations. Objectives: We reviewed clinical microbiological outcomes seven patients treated at “Agrippa Ionescu” Clinical Emergency Hospital between October...

10.3390/antibiotics13060550 article EN cc-by Antibiotics 2024-06-12

Results The following modes of transmission were identified: heterosexual – 130 (87.3%) patients and IDUs (injecting drug use) 19 (12.7%) patients. Out 149 patients, 94 (63.1%) detected late with CD4 counts 100000 copies/mL.

10.1186/1471-2334-14-s7-p17 article EN cc-by BMC Infectious Diseases 2014-10-15

We evaluated the clinical features, immunological and virological indices in HIV/AIDS–infected patients at detection antiretroviral therapy (HAART) initiation. We followed up 149 adult diagnosed with HIV/AIDS infection between years 1997-2011 supervised specialized department of Clinical Hospital Infectious Diseases “Toma Ciorba”. These received HAART since 2011. The late diagnosis is defined by presence AIDS associated diseases and/or level CD4 <350 cells/µL. Studying general features...

10.1186/1471-2334-14-s4-p14 article EN cc-by BMC Infectious Diseases 2014-05-01

Results The mean age of the patients was 30, and they were admitted in Clinical Hospital for Infectious Diseases “Toma Ciorba” July, 2013. source infection represented by cattle, which confirmed bacteriological method. occurred through contact with sick animals during slaughter. disease developed after an incubation period, lasted on average 9 days. first two fourth day from onset symptoms, one third other second following onset. All diagnosed anthrax, a cutaneous form, carbuncles, evolving...

10.1186/1471-2334-13-s1-p72 article EN cc-by BMC Infectious Diseases 2013-12-01

Introduction. Leukonostoc pseudomesenteroides, widespread in nature (soil, plants, milk, etc.), until recently was classified as a commensal microorganism, but from 1985 now several sporadic cases of infection with this pathogen have been described humans. Bacteremia Leuconostoc spp. are increasingly reported. Unique other sites also described: soft, lung, urinary, Central Nervous System tissues, etc. Most often, these reported patients cancer, and often considered opportunistic for acquired...

10.38045/ohrm.2023.1.10 article EN cc-by One Health & Risk Management 2023-01-01

Introduction. Viral hepatitis C (HCV) is a significant global health problem. The risk of developing chronic HCV up to 80% patients, whom 10-20% can develop liver cirrhosis or hepatocellular carcinoma which lead death. Treatment with direct-acting antiviral agents (DAAs) contributes sustained virological response (SVR) in 97-99% cases.

10.38045/ohrm.2020.1.02 article EN cc-by One Health & Risk Management 2020-03-31

Objectives. Liver fibrosis is a prognostic marker of the evolution hepatitis C virus infection, and imaging investigations are important in diagnosing assessing severity progression fibrosis. The purpose study was to evaluate efficacy direct-acting antiviral agents with/without Ribavirin, patients with cirrhosis  with liver after treatment. Materials methods. included 75 virus, divided into two groups, according duration treatment regimen: group I – Sofosbuvir Daclatasvir/Ledipasvir for 12...

10.5281/zenodo.4069374 article EN Arta Medica 2020-10-07

10.5281/zenodo.3700945 article EN cc-by Zenodo (CERN European Organization for Nuclear Research) 2020-01-15
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