A5026667249- Renal and related cancers
- Neuroblastoma Research and Treatments
- Renal cell carcinoma treatment
- Testicular diseases and treatments
- Sarcoma Diagnosis and Treatment
- Pluripotent Stem Cells Research
- Cancer, Hypoxia, and Metabolism
- Cancer therapeutics and mechanisms
- Tumors and Oncological Cases
- Cancer-related gene regulation
- Lung Cancer Research Studies
- Management of metastatic bone disease
- Protein Degradation and Inhibitors
Qilu Hospital of Shandong University
2024
Guangxi Medical University
2019-2021
First Affiliated Hospital of GuangXi Medical University
2019-2020
This study was performed to establish and validate a nomogram for predicting the overall survival in children with neuroblastoma.The latest clinical data of neuroblastoma Surveillance, Epidemiology, End Results (SEER) database extracted from 2000 2016. The cases included were randomly divided into training validation cohorts. curves drawn Kaplan-Meier estimator investigate influences certain single factors on survival. Also, least absolute shrinkage selection operator regression applied...
We explored the difference in expression of tubulin alpha 1b (TUBA1B) between Wilms’ tumor (WT) and normal tissues (NT) from in-house patients databases, to determine TUBA1B WT predictive pathways coexpressed genes. In-house RNA-sequencing data were performed with NT three our institute. Other four microarray also downloaded multiple public databases. The was analyzed by Student’s <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>t</mml:mi></mml:math>-test...
Primitive neuroectodermal tumors are rare, highly malignant small round cell belonging to the Ewing sarcoma family. The purpose of this article is present clinical manifestation, histology, treatment, and prognosis two primitive (PNETs) in extremely rare anatomic locations, abdominal wall vulva.Case 1 was a 66-month-old girl with lesions on wall; tumor size about 3.4 cm × 6.1 2 cm. patient underwent radical resection tumor. After operation, an alternating vincristine, doxorubicin,...
BACKGROUND:Wilms tumor, or nephroblastoma, is a malignant pediatric embryonal renal tumor that has poor prognosis. This study aimed to use bioinformatics data, RNA-sequencing, connectivity mapping, molecular docking, and ligand-protein binding identify potential targets for drug therapy in Wilms tumor. MATERIAL AND METHODS:Wilms non-tumor samples were obtained from high throughput gene expression databases, differentially expressed genes (DEGs) analyzed using the voom method limma package....
This study aimed to analyze the expression and prognosis of SRY-box transcription factor 11 (SOX11) in neuroblastoma (NB), as well biological function potential regulatory mechanism SOX11 NB.
Cuproptosis, a recently identified type of programmed cell death triggered by copper, has mechanisms in Wilms tumor (WT) that are not yet fully understood. This research focuses on examining the link between WT and Cuproptosis-related genes (CRGs), with goal developing predictive model for WT. Four gene expression datasets related to were sourced from GEO database. Subsequently, profiles CRGs extracted differential analysis immune infiltration studies. Utilizing 105 samples, clusters...
Background: Wilms tumour is the most common childhood renal cancer that requires development of better treatments. Nitidine chloride, a Chinese traditional medicine, could have therapeutic potential for tumour, however there been no studies to date. Methods: In-house RNA-seq was performed and public plus microarrays datasets were incorporated identifying landscape differentially expressed genes (DEGs) in tumour. Meanwhile, targets nitidine chloride acquired through combined analysis...