A5071993461- Advanced Nanomaterials in Catalysis
- Electrochemical sensors and biosensors
- Enzyme-mediated dye degradation
- Advanced biosensing and bioanalysis techniques
- melanin and skin pigmentation
- DNA and Nucleic Acid Chemistry
- Metal-Organic Frameworks: Synthesis and Applications
- Chemical and Physical Properties in Aqueous Solutions
- CRISPR and Genetic Engineering
- Analytical chemistry methods development
- Enhanced Oil Recovery Techniques
- Electrocatalysts for Energy Conversion
University of Limerick
2020-2022
Metal organic frameworks (MOFs) have been used to encapsulate an array of enzymes in a rapid and facile manner; however, the stability MOFs as supports for has not examined detail. This study examines with different compositions (Fe-BTC, Co-TMA, Ni-TMA, Cu-TMA, ZIF-zni) buffered solutions commonly enzyme immobilization biocatalysis. Stability was assessed via quantification release metals by inductively coupled plasma optical emission spectroscopy. The buffers had varied effects on MOF...
• Use of nanoporous gold electrode as support for diaphorase. Sensor the determination NADH utilising an osmium redox polymer and Limit detection 0.8 µM a linear range from 5 to 100 µM. is cofactor used by wide dehydrogenases. Measurement concentration widely measure activity enzymes. Extensive efforts have been made develop electrochemical sensors at low overpotentials avoid interferences. The development enzymatic biosensor described. Nanoporous electrodes were utilised immobilization...
The development of an electrochemical biosensor utilising a hairpin DNA probe labelled with methylene blue for the detection TP53 gene is described. Structural rearrangement into linear double strand induced different rates electron transfer that enabled increase in current upon hybridization. observed hybridization was studied at surface densities, times, concentration and length target sequences. selectively detected single nucleotide polymorphism affecting residue 175 p53 protein,...