A5022096485- Hepatocellular Carcinoma Treatment and Prognosis
- Nanoparticle-Based Drug Delivery
- Hormonal and reproductive studies
- Pharmacological Effects of Medicinal Plants
- Analytical Methods in Pharmaceuticals
- Microtubule and mitosis dynamics
- Chemotherapy-induced organ toxicity mitigation
- Heavy metals in environment
- Heavy Metals in Plants
- Pesticide Residue Analysis and Safety
University of Swabi
2023-2024
Traditional herbal medicines and health supplements have been empirically used to treat various disorders but most of them are not standardized experimentally validated for safety efficacy. In the present study, dosage forms traditional prescribed specific diseases were collected from local practitioners at different districts Khyber Pakhtunkhwa, Pakistan. The samples analyzed heavy metal, trace elements, minerals using atomic absorption spectroscopy. All tested contained metals, elements in...
The herbal products are considered safe due to their natural origin; however there reports about adulteration with synthetic steroids. In this particular study identification and quantification of selected steroidal adulterants including prednisolone, betamethasone, dexamethasone, triamcinolone acetonide testosterone in have been carried out using FTIR HPLC. samples were extracted by methanol, quantified high-performance liquid chromatography (HPLC). chromatographic separation was achieved...
The aim of this study is to improve the therapeutic effectiveness sorafenib loaded polymeric nanoparticles, surface modified by pluronic F-127 for treatment hepatocellular (HCC) and renal cell carcinomas (RCC). Poly Lactic co-glycolic acid (PLGA) was used encapsulate simple solvent evaporation technique. nanoparticles were prepared with different concentration keeping PLGA constant. There no incompatibilities among sorafenib, showing that integrity polymer, stabilizer drug remain same under...
This study was to designed develop sorafenib-loaded polymeric nanoparticles, surface-modified with pluronic F-127 for the effective treatment of hepatocellular (HCC) and renal cell carcinomas (RCC). Poly lactic coglycolic acid (PLGA) used encapsulate different concentrations sorafenib by a simple modified solvent evaporation method applying as surfactant coating agent. The preformulation characterization studies were conducted evaluate incompatibilities among sorafenib, PLGA F-127,...