A5008337899- Mathematical Biology Tumor Growth
- Angiogenesis and VEGF in Cancer
- Computational Fluid Dynamics and Aerodynamics
- Lattice Boltzmann Simulation Studies
- Advanced Numerical Methods in Computational Mathematics
- Fluid Dynamics and Heat Transfer
- Cellular Mechanics and Interactions
- Cancer Cells and Metastasis
- Access Control and Trust
- Job Satisfaction and Organizational Behavior
- Fluid Dynamics and Turbulent Flows
- Privacy-Preserving Technologies in Data
- Advanced Mathematical Modeling in Engineering
- Fluid Dynamics Simulations and Interactions
- Internet Traffic Analysis and Secure E-voting
- Nanoparticle-Based Drug Delivery
- Mathematical and Theoretical Epidemiology and Ecology Models
- Computer Graphics and Visualization Techniques
- Stability and Controllability of Differential Equations
- Computational Geometry and Mesh Generation
- Microtubule and mitosis dynamics
- Cancer, Hypoxia, and Metabolism
- Navier-Stokes equation solutions
- Gene Regulatory Network Analysis
- Mathematical Control Systems and Analysis
Wuhan Institute of Technology
2023-2025
First Affiliated Hospital of Anhui Medical University
2024
Anhui Medical University
2024
Tsinghua University
2023
Central Michigan University
2013-2023
Harbin Engineering University
2022
Tulane University
2022
The Seventh Affiliated Hospital of Sun Yat-sen University
2021
Sun Yat-sen University
2021
China Europe International Business School
2018
Abstract The intracellular and extracellular dynamics that govern tumor growth invasiveness in vivo remain poorly understood. Cell genotype phenotype, nutrient, oxygen, factor concentrations are key variables. In previous work, using a reaction-diffusion mathematical model based on variables directly describe cell cycle biology, we formulated the hypothesis morphology is determined by competition between heterogeneous proliferation caused spatial diffusion gradients, e.g., of nutrients,...
In this paper, we investigate the pharmacokinetics and effect of doxorubicin cisplatin in vascularized tumors through two-dimensional simulations. We take into account especially vascular morphological heterogeneity as well cellular lesion-level pharmacokinetic determinants like P-glycoprotein (Pgp) efflux cell density. To do construct a multi-compartment PKPD model calibrated from published experimental data simulate 2-h bolus administrations followed by 18-h drug washout. Our results show...
Utilizing role theory, we investigate the potential negative relationship between employees' moral ownership and their creativity, mitigating effect of ethical leadership in this relationship. We argue that employees higher on are likely to take more responsibility ensure nature own actions environment, inadvertently resulting them being less able think outside box be creative at work. However, propose leaders can relieve these from such agent role, allowing while staying moral. adopt a...
The designed pc- w LED device via the novel remote ‘capping’ packaging method using SMS:Ce/Tb/Sm and n -UV chip.
This work presents a continuous model for three early stage events in angiogenesis: initiation, sprout extension, and vessel maturation. We carefully examine the regulating mechanisms of vascular endothelial growth factor (VEGF) angiopoietins (Ang1 Ang2) on proliferation, migration maturation cells through their endothelium-specific receptor tyrosine kinase VEGFR2 Tie2, respectively. also consider effect platelet-derived factor-B (PDGF-B) proliferation pericytes. For factors, we present...
Online social networks have been used for a variety of rich activities in recent years, such as investigating potential employees and seeking recommendations high quality services service providers. In activities, trust is one the most critical factors decision-making users. literature, state-of-the-art prediction approaches focus on either dispositional tendency propagated pair-wise relationships along path or similarity rating values. However, there are other influential that should be...
The literature on abusive supervision largely presumes that employees respond to abuse in a relatively straightforward way: When is present, outcomes are unfavorable, and when absent, favorable (or, at least less unfavorable). Yet despite the recognition can vary over time, little consideration has been given how past experiences of may impact ways react it its absence) present. This notable oversight, as widely acknowledged create context against which present compared. By applying temporal...
Online trading takes place in a very complex environment full of uncertainty which deceitful service providers or sellers may strategically change their behaviors to maximize profits. The proliferation deception cases makes it essential and challenging model the dynamics provider predict trustworthiness transactions. Recently, probabilistic trust models have been used assist decision making computing environments. Although typical Hidden Markov Model (HMM) has provider's behavior dynamics,...