A5021925215- Ovarian cancer diagnosis and treatment
- Intraperitoneal and Appendiceal Malignancies
- Endometrial and Cervical Cancer Treatments
- Endometriosis Research and Treatment
- Sympathectomy and Hyperhidrosis Treatments
- Renal cell carcinoma treatment
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Ultrasound in Clinical Applications
- Estrogen and related hormone effects
- Surgical Sutures and Adhesives
- Cardiovascular and exercise physiology
- BRCA gene mutations in cancer
- Radiation Dose and Imaging
- Global Health Workforce Issues
- Colorectal Cancer Screening and Detection
- Wound Healing and Treatments
- Menopause: Health Impacts and Treatments
- Sports Performance and Training
- Nasal Surgery and Airway Studies
- Pleural and Pulmonary Diseases
- Medical Education and Admissions
- Dermatological and Skeletal Disorders
- Global Healthcare and Medical Tourism
University Hospitals of Derby and Burton NHS Foundation Trust
2019-2025
Royal Derby Hospital
2013-2025
University of Nottingham
2020-2024
Doctors Hospital at Renaissance
2024
Cwm Taf University Health Board
2021
Christ the King Seminary
2018
Birmingham City Hospital
2016-2018
Capital University
2018
Pennsylvania State University
2013
The Royal Wolverhampton NHS Trust
2012
Abstract Purpose To determine the rate of precancer and cancer in women presenting with PMB who have a visually atrophic endometrium at hysteroscopy assess value endometrial biopsy this situation adequacy samples obtained. Methods Retrospective reviews all patients had presented an ET > / = 4 mm or < focal changes irregular features between 2013 2024 University Hospitals Derby Burton were included ( n 1096). Patients previously unclear findings excluded. The histology result was...
Ovarian cancer survival in the UK lags behind comparable countries. Results from ongoing National Cancer Audit feasibility pilot (OCAFP) show that approximately 1 4 women with advanced ovarian (Stage 2, 3, and unstaged cancer) do not receive any anticancer treatment only 51% England international standard of care treatment, i.e., combination surgery chemotherapy. The audit has also demonstrated wide variation percentage receiving for cancer, be it or chemotherapy across 19 geographical...
To determine which descriptors of cytoreductive surgical extent in advanced ovarian cancer (AOC) best predict postoperative morbidity.Retrospective notes review.A gynaecological centre the UK.Six hundred and eight women operated on for AOC over a period 114 months at tertiary centre, between 16 August 2007 February 2017.Outcome data were analysed by six approaches to classify surgery: standard/ultra-radical surgery; standard/radical/supra-radical presence/absence gastrointestinal resections;...
To investigate the impact of serum albumin (at diagnosis and pre-operatively) on survival in patients undergoing cytoreductive surgery for advanced ovarian cancer(AOC) whether improvement achieved following neoadjuvant chemotherapy (NACT) affects overall (OS).Outcomes 441 who underwent cytoreduction AOC were reviewed. Albumin was recorded at pre-operatively. Further analysis performed if hypoalbuminaemic diagnosis.Analysis stratified according to patientreceived primary debulking (PDS) or...
Studies investigating the safety of hormone replacement therapy in cervical cancer have predominantly included patients with squamous disease. Pathological studies identified estrogen receptor positivity adenocarcinomas. A recent small case-control study suggested a trend towards reduced survival Our objective was to determine if use treated for adenocarcinomas is detrimental survival.A retrospective review all women under age 50 stage 1B-2B diagnosed between 1 November 2000 and 24 September...
Key content Sentinel lymph node (SLN) biopsy is an alternative to systematic lymphadenectomy in the surgical staging of gynaecological malignancy. It recommended management vulval cancer and increasingly used endometrial cervical cancer. SLN failed mapping algorithms require that side‐specific should be performed case mapping, suspicious nodes are removed. Ultrastaging protocols improve detection lymph‐node metastasis for pathological processing SLNs. Learning objectives To understand...
These guidelines have been developed jointly by the British Gynaecological Cancer Society and Menopause to provide information for all healthcare professionals managing women treated gynaecological cancer. Menopausal symptoms can a significant impact on quality of life women. therapies, including surgery, pelvic radiotherapy, chemotherapy endocrine therapy, affect ovarian function. The benefits risks using hormone replacement therapy are considered cancer type with guidance HRT optimal time...
The aim of this study was to determine whether the age-adjusted Charlston co-morbidity index (ACCI) can predict post-operative complications, adjuvant chemotherapy usage and overall survival (OS) in patients with advanced epithelial ovarian cancer (AOC) treated neoadjuvant (NACT). A review performed all cytoreductive surgeries between 16/8/07-3/2/14 for AOC at a UK Cancer Centre. All were stratified by ACCI into three groups: Low (0–1), Intermediate (2–3) High (≥4). Of 293 cases distribution...
Epidurals are frequently used as part of multi-modal perioperative analgesia. They widely accepted providing excellent pain relief but associated with side-effects, have a significant failure rate and can limit patient's mobility. We report on our use rectus sheath catheters (RSCs), in conjunction intravenous opiate via patient controlled analgesia (PCA), means post-laparotomy for gynaecological oncological patients. Our experience is that this offers an alternative method equivalent...
CHORUS and EORTC55971 trials demonstrated that neoadjuvant chemotherapy followed by interval debulking surgery (IDS) or primary (PDS) offered the same survival rates. These have since been criticised due to poor surgical complexity. We compared overall (OS), progression free (PFS), platinum sensitivity in advanced ovarian cancer (AOC) patients undergoing IDS PDS, who had received either intermediate high complexity achieve complete cytoreduction.All with AOC treated between February 2014 May...
This study assessed Cardiopulmonary Exercise Testing (CPET) in predicting oncological outcomes, post-operative recovery and complications advanced ovarian cancer (AOC) cytoreductive surgery. We reviewed all patients who had CPET prior to AOC surgery with evidence of upper abdominal disease on preoperative imaging at the University Hospitals Derby Burton (UHDB) between August 2016 July 2019. Patients were stratified by AT maximum VO2 levels. 43 identified. showed no relationship major...