A5023289702- Immunotherapy and Immune Responses
- vaccines and immunoinformatics approaches
- Alzheimer's disease research and treatments
- Andrographolide Research and Applications
- Nicotinic Acetylcholine Receptors Study
- Electrospun Nanofibers in Biomedical Applications
- Drug Transport and Resistance Mechanisms
- Marine Invertebrate Physiology and Ecology
- Pediatric Hepatobiliary Diseases and Treatments
- Phytochemical and Pharmacological Studies
- RNA modifications and cancer
- Fatty Acid Research and Health
- T-cell and B-cell Immunology
- Tryptophan and brain disorders
- Silk-based biomaterials and applications
- Circadian rhythm and melatonin
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Venomous Animal Envenomation and Studies
- Peptidase Inhibition and Analysis
- Nanocomposite Films for Food Packaging
- Dietary Effects on Health
- Monoclonal and Polyclonal Antibodies Research
Mahidol University
2015-2025
Chulalongkorn University
2021
University of Liverpool
2021
Alzheimer's disease (AD) is prevalent in the elderly population and characterized by intracellular accumulation of neurofibrillary tangles (NFTs), composed tau proteins, extracellular deposition beta-amyloid protein (Aβ). The present study aimed to investigate neuroprotective effects melatonin on Aβ42-induced AD-like pathology SH-SY5Y cell lines. To assess Aβ42-exposed cells, we performed a proteomics analysis altered expression Aβ42-treated with or without Pretreatment, using label-free...
Andrographolide, a bioactive phytochemical from Andrographis paniculata, is emerging as promising anticancer agent against various cancers. This study aims to investigate activities of andrographolide cholangiocarcinoma (CCA) and understand the underlying mechanism. The anti-proliferative activity was evaluated in range cell lines including HuCCA-1, KKU-100, KKU-M213, RMCCA-1. anti-migration corresponding mechanism were studied highly metastatic KKU-M213 cells. results indicated that...
Elaeagnus latifolia (EL) is a wild fruit known for containing several health-promoting compounds. This study aimed to evaluate the effects of EL extract on high-fat diet (HFD)-induced obesity and lipopolysaccharide (LPS)-activated macrophages. Mice fed an HFD given 10 weeks exhibited significantly lower body weight, reduced lipid accumulation, diminished oxidative stress in adipocytes, decreased macrophage infiltration compared those not receiving extract. Moreover, activated transcription...
MHC-peptide binding prediction has been widely used for understanding the immune response of individuals or populations, each carrying different MHC molecules as well development immunotherapeutics. The results from tools are mostly reported a predicted affinity (IC50) and percentile rank score, global thresholds e.g. IC50 value < 500 nM 2% generally recommended distinguishing peptides non-binding peptides. However, it is difficult to evaluate statistically probability an individual peptide...