- Phytochemistry and Biological Activities
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Biological Activity of Diterpenoids and Biflavonoids
- Bioactive Natural Diterpenoids Research
- Phytochemical Studies and Bioactivities
- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Bioactive natural compounds
- Medicinal Plants and Neuroprotection
- Synthesis and Characterization of Heterocyclic Compounds
- Morinda citrifolia extract uses
- Plant-based Medicinal Research
University Frères Mentouri Constantine 1
2013-2024
Centre National de la Recherche Scientifique
2017
Institut de Chimie Moléculaire de Reims
2017
University of Constantine 3
2013-2014
A previously undescribed phenolic sulphate ester, potassium 34-dihydroxy-3-methoxybenzoic acid methyl ester-5-sulphate (1), along with nine known flavonoids, kaempferol-3-O-potassium sulphate-4′,7-dimethyl ether (2), kaempferol-4′,7-dimethyl (3), rhamnocitrin-3-O-potassium (4), rhamnocitrin (5), kaempferol (6), quercetin (7), afzelin (8), quercetin-3-O-α-l-rhamnopyranoside (9) and luteolin-3′-O-potassium (10) were isolated from the aerial parts of Tamarix balansae. Structures elucidation was...
A new phorbol-type diterpene ester, 4,20-dideoxy-4α-phorbol-12β-acetate-13α-isobutyrate, in addition to 11 known compounds were isolated from the latex and roots of Euphorbia clementei Boiss. Structure elucidation was performed by comprehensive 1D 2D NMR analyses (1H 13C NMR, COSY, ROESY, HSQC HMBC experiments), mass spectrometry (HR-ESI-MS) comparison with literature data. The inhibitory activity all evaluated against promyelocytic leukemia HL60 human erythromyeloblastoid K562 cell lines...
A hemisynthesis 'in situ' reaction of (thio)barbituric acids with an α,β-unsaturated aldehyde using perillaldehyde from Ammodaucus leucotrichus essential oil, afforded chromeno-pyrimidine derivatives B-1 and B-2. The was carried out in water water/ethanol medium without a catalyst. obtained pyrimidines were identified by their spectral 1H,13C, Dept-135, HMBC, HSQC, COSY, NOESY 2D. antioxidant activity both compounds evaluated different vitro methods (DPPH, ABTS, CUPRAC). hemisynthesized...
A new C-glycosylflavone, identified as 6"'-O-acetylisospinosin (1), was isolated from the aerial parts of Cladanthus mixtus together with 30 known compounds. The structures these compounds were established by interpretation their spectral data, mainly UV, 1D and 2D NMR spectroscopic methods including (1H 13C NMR, COSY, ROESY, HSQC HMBC experiments), ESI-MS, comparison literature data.