- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Liver Disease and Transplantation
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Porphyrin Metabolism and Disorders
- Heme Oxygenase-1 and Carbon Monoxide
- DNA Repair Mechanisms
- Pelvic floor disorders treatments
- Stroke Rehabilitation and Recovery
- Sex work and related issues
- Pressure Ulcer Prevention and Management
- Neonatal Health and Biochemistry
- Congenital Anomalies and Fetal Surgery
- Blood properties and coagulation
- Clinical practice guidelines implementation
- Healthcare Operations and Scheduling Optimization
- Hernia repair and management
- Animal health and immunology
- Heparin-Induced Thrombocytopenia and Thrombosis
- Stoma care and complications
- COVID-19 and healthcare impacts
- Acute Kidney Injury Research
- Neurosurgical Procedures and Complications
Mayo Clinic
2022-2024
Mayo Clinic in Arizona
2016-2023
Division of Chemistry
2022
Mayo Clinic Hospital
2021
Northwestern Medicine
2021
University of Southern California
2017-2018
Abstract Kidney transplant (KT) outcomes from high kidney donor profile index (KDPI ≥85%) donors with acute injury (AKI) remain underreported. KT 172 KDPI Acute Injury Network (AKIN) stage 0‐1 and 76 AKIN 2‐3 a single center were retrospectively assessed. The cohort had more delayed graft function (71% vs. 37%, p < .001). At one year, there no differences in the estimated glomerular filtration rate (44 ± 17 46 18, = .42) or fibrosis on protocol biopsy (ci, .85). Donor terminal creatinine...
Donation after circulatory death (DCD) liver transplantation (LT) outcomes have been attributed to multiple variables, including procurement surgeon recovery techniques. Outcomes of 196 DCD LTs at Mayo Clinic Arizona were analyzed based on graft by a from our center (transplant team [TPT]) versus local (non-TPT [NTPT]). A standard technique was used for all TPT livers. The the NTPT left discretion that surgeon. total 129 (65.8%) grafts recovered TPT, 67 (34.2%) NTPT. Recipient age (p =...
Concerns regarding outcomes and early resource utilization are potential deterrents to broader use of kidneys at risk for delayed graft function (DGF). We assessed specific with DGF that required readmission following transplant. Three groups were identified: 1) recipients not requiring readmission, 2) having an isolated 3) ≥2 readmissions. Most either a single (26.8%, n = 247) or no (56.1%, 517); 17.1% (n 158), had Recipients readmissions likely be diabetic (53.8%, p 0.04) have longer...
Both variegate and acute intermittent porphyria can manifest with various neurological symptoms. Although symptomatic seizures have been previously described, they are typically tonic-clonic focal impaired awareness seizures. Convulsive status epilepticus epilepsia partialis continua rare described on a case report basis. To our knowledge, there no reported cases describing non-convulsive (NCSE) electroencephalogram (EEG) documentation in the setting of crisis. We unique presentation NCSE,...
Abstract Early pancreas loss in simultaneous pancreas–kidney (SPK) transplants has been associated with longer perioperative recovery and reduced kidney allograft function. We assessed the impact of early failure on transplant outcomes a contemporary cohort SPK patients ( n = 218). occurred 12.8% 28) recipients. Delayed graft function (DGF) was more common (21.4% vs. 7.4%, p 0.03) group, but there were no differences hospital length stay (median 6.5 7.0, 0.22), surgical wound complications...
To identify barriers to inpatient alteplase administration and implement an interdisciplinary program reduce time systemic thrombolysis.Compared with patients presenting the emergency department acute ischemic stroke (AIS), inpatients are delayed in receiving for thrombolysis. Institutional AIS metrics were extracted from electronic medical records of as alert. All who received included analysis. A gap analysis was used assess institutional deficiencies. An intervention initiated address...
Abstract Heterochromatin is mostly composed of long stretches repeated DNA sequences prone to ectopic recombination during double-strand break (DSB) repair. In Drosophila , ‘safe’ homologous (HR) repair heterochromatic DSBs relies on a striking relocalization sites the nuclear periphery. Central understanding heterochromatin ability investigate 4D dynamics (movement in space and time) sites. A specific challenge these studies preventing phototoxicity photobleaching effects while imaging...
Abstract Context The risk of gestational diabetes mellitus (GDM) in twin pregnancies is more than double that singleton pregnancies. Although present unique challenges for fetal growth and prenatal management, the approach to GDM diagnosis treatment same regardless plurality. Data on pregnancy outcomes individuals with a are limited conflicting. Objective To describe maternal characteristics associated assess compared unaffected by GDM. Methods A retrospective cohort study was conducted at...
Liver acceptance patterns vary significantly between transplant centers. Data pertaining to outcomes of livers declined by local and regional centers allocated nationally remains limited.The objective was compare post-liver liver allografts transplanted as a result national local-regional allocation.This retrospective evaluation 109 used for single center. Outcomes grafts were compared standard allocation (N = 505) during the same period.Recipients had lower model end stage disease scores...
Few medical schools incorporate formal education on human trafficking (HT) and sex (ST) into their curriculum. Our objective was to develop, implement, evaluate HT ST in the first-year student curriculum.The curriculum included a standardized patient (SP) experience lecture. As part of mandatory sexual health course, students interviewed an SP who presented with red flags for then participated discussion led by physician-facilitator observed small group setting. A multiple-choice survey...
Dual kidney transplantation (DKT), utilizing two adult kidneys from the same donor for one recipient, has been used as a way to expand available pool. These often come high Kidney Donor Profile Index donors (KDPI > 85%). Data comparing outcomes between KDPI DKT and single transplants (SKT) remain limited. We assessed of 336 performed at our center; 11.0% (n = 37) were DKT. Recipients older (P .02) had higher score (median 96% vs. 91%, P < .0001). operative time was compared SKT (+1.4 hours,...
A 23-year-old woman, with a history of cerebral venous sinus thrombosis (CVST) on warfarin, presented acute septic hemarthrosis, requiring surgery. cerebrovascular consultation was placed for anticoagulation recommendations. Brain magnetic resonance venography revealed hypoplastic right transverse (figure). Anticoagulation discontinued. Given her headache and papilledema, acetazolamide started due to clinical suspicion idiopathic intracranial hypertension (IIH).
Sunday, April 26April 14, 2020Free AccessAn Interdisciplinary Intervention to Improve Time Systemic Thrombolysis for Inpatient Acute Ischemic Strokes (5513)Harn Shiue, PharmD, MSc, Andrew Pines, MA, Devika Das, MS, Vanesa Vanderhye, MSN, RN, Shubhang Bhatt, BS, Sara Dawit, MD, and Kara Sands, MDAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.5513 Letters the Editor
A five-year-old HF crossbred cattle was presented to the Veterinary Clinical Complex, MJF College of and Animal Science, Chomu, Jaipur, with a large external swelling in ventral abdominal region for week.The clinical examination revealed soft reducible hernial ring on ventro-abdominal region, case confirmed as hernia.The animal restrained left lateral recumbency under sedation xylazine infiltration local anaesthetic at site.Surgical herniorrhaphy done by using synthetic non-absorbable...