A5062164377- RNA and protein synthesis mechanisms
- Machine Learning in Bioinformatics
- Expert finding and Q&A systems
- Genomics and Phylogenetic Studies
- Advanced Graph Neural Networks
- Epigenetics and DNA Methylation
- Recommender Systems and Techniques
- RNA modifications and cancer
Tianjin University
2023
Zhengzhou University of Light Industry
2021-2023
Abstract Lysine glutarylation (Kglu) is a newly discovered post-translational modification of proteins with important roles in mitochondrial functions, oxidative damage, etc. The established biological experimental methods to identify sites are often time-consuming and costly. Therefore, there an urgent need develop computational for efficient accurate identification sites. Most the existing only utilize handcrafted features construct prediction model do not consider positive impact...
Knowledge concept recommendation is a kind of fine-grained in massive open online courses (MOOCs) scenario, user interaction data has the characteristics strong collaborative signals and imbalanced interactions. This leads to single reduced accuracy. Recently, ability contrastive learning (CL) mitigating imbalance recommender systems received widespread attention. CL requires use augmentation methods generate different views. Existing (1) augment only at topology or feature level ignoring...
DNA N4-methylcytosine(4mC) plays an important role in numerous biological functions and is a mechanism of particular epigenetic importance. Therefore, accurate identification the 4mC sites sequences necessary to understand functional mechanism. Although some effective calculation tools have been proposed identifying sites, it still challenging improve accuracy generalization ability. there great need build computational tool accurately identify position sites. Hence, this study novel...