A5026047298- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Fluid Dynamics and Vibration Analysis
- Aortic Disease and Treatment Approaches
- Biomimetic flight and propulsion mechanisms
- Fluid Dynamics and Turbulent Flows
- Cardiac Structural Anomalies and Repair
- Lattice Boltzmann Simulation Studies
- Mechanical Circulatory Support Devices
- Pulmonary Hypertension Research and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Aerodynamics and Fluid Dynamics Research
- Advanced MRI Techniques and Applications
- Aerosol Filtration and Electrostatic Precipitation
- Congenital heart defects research
- Fluid Dynamics Simulations and Interactions
- Renal and Vascular Pathologies
- Coronary Interventions and Diagnostics
- Cardiovascular Issues in Pregnancy
- Particle Dynamics in Fluid Flows
Worcester Polytechnic Institute
2024-2025
University of Massachusetts Lowell
2020-2025
The Wallace H. Coulter Department of Biomedical Engineering
2016-2023
Georgia Institute of Technology
2015-2023
Emory University
2017-2021
Children's Hospital of Philadelphia
2019
University of Kansas
2012-2017
Kansas State University
2009-2010
A two-dimensional numerical study is performed to investigate the relation between direction of a deflected wake and vortex pairing mechanisms. The deflection angle can be correlated with two effective phase velocities defined represent trends symmetry breaking holding, respectively. increases strength pairs, which associated heaving amplitude, frequency, free stream Reynolds number. Furthermore, not only influence Strouhal number but also those motion components – amplitude frequency are...
<h3>Objective</h3> Exercise intolerance afflicts Fontan patients with total cavopulmonary connections (TCPCs) causing a reduction in quality of life. Optimising TCPC design is hypothesised to have beneficial effect on exercise capacity. This study investigates relationships between geometries and haemodynamics performance. <h3>Methods</h3> included 47 who completed metabolic stress test cardiac magnetic resonance (CMR). Phase-contrast CMR images were acquired immediately following supine...
To investigate the incidence and significant ultrasound parameter changes of coarctation aorta (CoA) among fetuses with suspected CoA, pregnant women CoA on prenatal examination were prospectively enrolled. The presence was confirmed after birth by computed tomographic angiography, ultrasound, surgery or autopsies. parameters analyzed. Among 133 44 (33.1%) delivery an age range 20–41 (31.36 ± 4.73) years a gestational 20.5–36.5 (27.35 4.52) weeks, 89 (66.9%) to have false-positive matched (P...
Abstract The Fontan procedure, essential for newborns with single ventricle malformations, establishes a total cavopulmonary connection (TCPC). Understanding TCPC hemodynamics is critical evaluating surgical outcomes. However, the intricate flow collisions within present significant challenge. While computational fluid dynamics (CFD) offers insight into these mechanics, its inefficiency limits clinical application. Machine learning (ML) show promise in overcoming this limitation. This study...
Total cavopulmonary connection (TCPC) hemodynamics has been hypothesized to be associated with long-term complications in single ventricle heart defect patients. Rigid wall assumption commonly used when evaluating TCPC using computational fluid dynamics (CFD) simulation. Previous study evaluated impact of compliance on extra-cardiac fluid-structure interaction (FSI) However, the ignoring presumably more compliant intra-atrial is not fully understood. To narrow this knowledge gap, aims...
<p>This paper studied the Riemann problem for non-isentropic Chaplygin gas magnetogasdynamics equations and investigated general asymptotic behavior of its solutions. Due to influence source term in equations, solutions are no longer self-similar. We performed analysis after eliminating by using a velocity transformation. When initial data density satisfied condition $ v_–\frac{1}{\rho_-}\geq v_++\frac{1}{\rho_+} $, as reciprocal magnetic flux \mu tended zero, converged delta shock...
Hemodynamics in total cavopulmonary connections (TCPCs) are closely linked to patient outcomes. Previous studies have simplified assessments by focusing solely on the TCPC itself, overlooking effects of upstream flow mixing. Consequently, impact mixing hemodynamics remains poorly understood. In this study, we quantified for first time effect from all vessels TCPC. Hemodynamic metrics were obtained using a cutting-edge computational platform that considers patient-specific anatomy, peripheral...
Objective We previously described lower leg lean mass Z-scores (LLMZ) in Fontan patients associated with worse peak oxygen consumption on metabolic exercise testing. hypothesised that LLMZ correlates indexed systemic flow (Qsi) and cardiac index (CI) magnetic resonance (eCMR). Methods Thirteen had LLM measured by dual-energy X-ray absorptiometry within mean 40 (range 0–258) days of eCMR. was converted to sex race-specific based healthy reference data. Ventricular volumes measurements the...