A5033020123- Adipose Tissue and Metabolism
- High Altitude and Hypoxia
- Animal Nutrition and Physiology
- Cancer-related molecular mechanisms research
- Neuroscience of respiration and sleep
- Molecular Biology Techniques and Applications
- Genetic and phenotypic traits in livestock
- Meat and Animal Product Quality
- Livestock and Poultry Management
- MicroRNA in disease regulation
- Rangeland Management and Livestock Ecology
- Cancer, Hypoxia, and Metabolism
- Peroxisome Proliferator-Activated Receptors
- Genetic Mapping and Diversity in Plants and Animals
- Viral Infections and Immunology Research
- Physiological and biochemical adaptations
- Metabolomics and Mass Spectrometry Studies
- Animal Genetics and Reproduction
- Muscle metabolism and nutrition
- Muscle Physiology and Disorders
- Viral Infections and Vectors
- Diet and metabolism studies
- Synthesis and bioactivity of alkaloids
- Veterinary Equine Medical Research
- TGF-β signaling in diseases
Tibet University
2016-2025
Tibetan Traditional Medical College
2024
Huazhong Agricultural University
2015-2017
University of Agriculture Faisalabad
2017
National Animal Husbandry Service
2011
China Agricultural University
2009-2010
Abstract Growth rate and meat quality, two economically important traits in pigs, are controlled by multiple genes biological pathways. In the present study, we performed a proteomic analysis of longissimus dorsi muscle from six-month-old pigs Chinese native mini-type breeds (TP DSP) introduced western (YY LL) using isobaric tag for relative absolute quantification (iTRAQ). total, 4,815 peptides corresponding to 969 proteins were detected. Comparison expression patterns between TP-DSP YY-LL...
ABSTRACT Pigs are important agricultural animals whose growth rate and meat production performance related to muscle development. Musculoskeletal embryonic nuclear protein 1 (MUSTN1) participates in various biological processes, including myogenesis animals, but the physiological functions mechanisms of porcine MUSTN1 on development unclear; thus, we aimed elucidate them. We found that was highly expressed muscles fast‐growing pigs. Functionally, promoted myoblast proliferation...
Transcriptome profiles established using high-throughput sequencing can be effectively used for screening genome-wide differentially expressed genes (DEGs). RNA sequences (from RNA-seq) and microRNA miRNA-seq) from the tissues of longissimus dorsi muscle two indigenous Chinese pig breeds (Diannan Small-ear [DSP] Tibetan [TP]) introduced (Landrace [LL] Yorkshire [YY]) were examined HiSeq 2000 to identify compare differential expression functional related growth lipid deposition. We obtained...
Tibetan pigs that inhabit the Plateau exhibit striking phenotypic and physiological differences from lowland pigs, have adapted well to extreme conditions. However, mechanisms involved in regulating gene expression at high altitude these animals are not fully understood. In this study, we obtained transcriptomic proteomic data heart tissues of Yorkshire raised highlands (TH YH) lowlands (TL YL) via RNA-seq iTRAQ (isobaric tags for relative absolute quantitation) analyses, respectively....
Tibetan chickens, a unique chicken breed native to high altitude, have good adaptation hypoxia. The experiment was conducted determine the adaptive blood characteristics in chickens. Fertile eggs from and Dwarf Recessive White chickens were incubated, chicks reared until 10 wk of age at low altitude (100 m) (2,900 m). At 1 d 2, 6, age, hematological characteristics, gas value, volume measured. had more red cells (RBC), smaller mean cell volume, lower pH partial pressure oxygen, higher carbon...
Tibetan pigs, which inhabit the Plateau, exhibit distinct phenotypic and physiological characteristics from those of lowland pigs have adapted well to extreme conditions at high altitude. However, genetic epigenetic mechanisms hypoxic adaptation in animals remain unclear. Whole-genome DNA methylation data were generated for heart tissues grown highland (TH, n = 4) (TL, 4), as Yorkshire (YH, (YL, using methylated immunoprecipitation sequencing. We obtained 480 million reads detected 280679,...
We investigated Japanese encephalitis virus (JEV) prevalence in high-altitude regions of Tibet, China, by using standard assays to test mosquitoes, pigs, and humans. Results confirmed that JEV has spread these areas. Disease prevention control strategies should be used along with surveillance limit Tibet.
Toxocara vitulorum has been rarely reported in yaks at high altitudes and remote areas of Sichuan Province Tibetan Plateau China. The current study was designed to investigate the prevalence, associated risk factors, phylogenetic characteristics T. yak calves on Qinghai plateau. Fecal samples were collected from 891 examined for presence eggs by McMaster technique. A multivariable logistic regression model employed explore variables potentially with exposure infection. specimens feces...
Tibetan pigs from the Plateau are characterized with a significant phenotypic difference relative to lowland pigs. In this study, of fatness and fatty acid composition traits was observed between Yorkshire To uncover involved mechanism, expression profile long noncoding RNAs (lncRNAs) genes compared them. After serial filtered steps, 1,964 lncRNAs were obtained through our computational pipeline. total, 63 715 identified be differentially expressed. Evidence cis- trans-targeting analysis...
Abstract The growth of pigs is an important economic trait that involves multiple genes and coordinated regulatory mechanisms. rate potential skeletal muscles are largely decided by embryonic myofiber development. Tibetan pig (TP) a mini‐type breed has divergent phenotype in adult body weight with Wujin (WJ) large White (LW). In the current study, transcriptome (using RNA‐seq) proteome isobaric tag for relative absolute quantification [iTRAQ]) data from prenatal muscle tissues were analyzed...
Several geographically isolated populations of Tibetan pigs inhabit the high-altitude environment Plateau. Their genetic relationships, contribution to pool diversity, and their origin domestication are unclear. In this study, whole-genome re-sequencing data from 10 pig were collected analyzed. Population analyses revealed limited differentiation among populations. Evidence deleterious variant analysis indicated that population-specific variants major component all mutational loci....
In this study, the differences in protein profiles between livers of Shannan Tibetan pigs (SNT), Linzhi (LZT) and Jiuzhaigou (JZT) were comparatively analyzed by tandem mass spectrometry-labeling quantitative proteomics. A total 6804 proteins identified: 6471 quantified 1095 screened as differentially expressed (DEPs). Bioinformatics analysis results show that, compared with JZT livers, up-regulated DEPs SNT LZT mainly promoted hepatic detoxification through steroid hormone biosynthesis...
The experiments were conducted to assess how hatching performance is affected by chicken breeds and environment of high altitude analyze the vital factor low hatchability at a 2,900-m altitude. Eggs Tibetan Dwarf chickens incubated conditions normobaric normoxia, hypoxia, hypobaric supplemental O2 (hypobaric normoxia) during whole incubation or 0 7, 8 14, 15 22 d incubation, respectively. results showed that had greater (79.72%), lower water loss (12.90%), relative embryo weight (38.08%),...
Subcutaneous fat thickness and intramuscular content are closely related to meat production quality in the pig industry. Adipogenesis adipocytes from subcutaneous tissues involves different genes regulatory mechanisms. Analyzing data of mRNA miRNA transcriptomes during differentiation these two sources will help identify mechanisms deposition. In this study, RNA sequencing technology was used analyze differential expression miRNAs at days 0, 2, 4, 8 differentiation. We mainly attributed...
Abstract Introgression events and population admixture occurred among Sus species across the Eurasian mainland in Middle Pleistocene, which reflects local adaption of different populations contributes to evolutionary novelty. Previous findings on these introgressions were largely based extensive genome-wide single-nucleotide polymorphism information, ignoring structural variants (SVs) as an important alternative resource genetic variations. Here, we profiled SVs explored formation...
To study the effects of different feed additives on weaning stress Tibetan piglets, we selected 28 healthy, 30-day-old weaned piglets and divided them into four groups, namely, control group (basal without any antibiotic additions) (Nor), with addition lincomycin (Ant), fifteen-flavor black pills medicine (Tib), fecal bacterial supernatant (Fec). We measured growth performance, blood physiological indexes, metabolomics. The results showed that Ant, Tib, Fec groups significantly reduced ratio...