A5018064840- Cardiac Imaging and Diagnostics
- Advanced X-ray and CT Imaging
- Advanced MRI Techniques and Applications
- Radiation Dose and Imaging
- Cerebrospinal fluid and hydrocephalus
- Spinal Dysraphism and Malformations
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Function and Risk Factors
- Viral Infections and Immunology Research
- Cardiac Valve Diseases and Treatments
- Venous Thromboembolism Diagnosis and Management
- Fetal and Pediatric Neurological Disorders
- Aortic Disease and Treatment Approaches
- Medical Imaging Techniques and Applications
- Head and Neck Surgical Oncology
- Cardiac Arrhythmias and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Coronary Interventions and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Radiology practices and education
- Ultrasound in Clinical Applications
- Cerebrovascular and Carotid Artery Diseases
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Sphingolipid Metabolism and Signaling
University Hospital Cologne
2016-2025
University of Cologne
2014-2025
Centrum für Integrierte Onkologie
2018-2025
Ruhr University Bochum
2021
Applications Research (United States)
2021
Philips (United Kingdom)
2021
Philips (United States)
2021
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2020
University of Münster
2008-2015
University Hospital Münster
2011-2013
Published under a CC BY 4.0 license.
Background Errors in radiology reports may occur because of resident-to-attending discrepancies, speech recognition inaccuracies, and large workload. Large language models, such as GPT-4 (ChatGPT; OpenAI), assist generating reports. Purpose To assess effectiveness identifying common errors reports, focusing on performance, time, cost-efficiency. Materials Methods In this retrospective study, 200 (radiography cross-sectional imaging [CT MRI]) were compiled between June 2023 December at one...
Cerebrospinal fluid (CSF) dynamics in the cervical spinal subarachnoid space (SSS) have been thought to be important help diagnose and assess craniospinal disorders such as Chiari I malformation (CM). In this study we obtained time-resolved three directional velocity encoded phase-contrast MRI (4D PC MRI) healthy volunteers four CM patients compared 4D measurements subject-specific 3D computational (CFD) simulations. The CFD simulations considered geometry rigid-walled did not include small...
Introduction Phase contrast MRI allows for the examination of complex hemodynamics in heart and adjacent great vessels. Vortex flow patterns seem to play an important role certain vascular pathologies. We propose two- three-dimensional metrics objective quantification aortic vortex blood 4D phase MRI. Materials Methods For two-dimensional vorticity assessment, a standardized set 6 regions-of-interest (ROIs) was defined throughout course aorta. each ROI, heatmap time-resolved values ω→=∇v→...
Objectives In-stent restenosis (ISR) is one of the main long-term complications after coronary stent placement, and ability to evaluate ISR noninvasively using computed tomography (CT) angiography remains challenging. For this application, spectral photon-counting CT (SPCCT) has potential increase image quality reduce artifacts due its advanced detector technology. Our study aimed verify technical clinical a novel SPCCT prototype an phantom setup. Materials Methods Soft plaque-like (45 HU;...
Numerous studies support the notion that an activation of sphingomyelinases and a subsequent increase concentration bioactive lipid mediator ceramide are critical in concert inflammatory stimuli to induction apoptosis during inflammation. Here we show patients with severe sepsis exhibit enhanced sphingolytic activity comparison controls [262 pmol/(mlxh) vs. 123.6 pmol/(mlxh), P<0.005]. During clinical course, further was paralleled by severity illness fatal outcome. Moreover, oxidative...
Sphingomyelinases (SMase) are key regulating enzymes of the intracellular and paracrine ceramide second messenger system that mediates immune response to inflammatory cytokines oxidative stress. Vascular endothelial cells a rich regulatable source secretory SMase (S-SMase). Chronic heart failure (CHF) is state dysfunction latent activation. The significance S-SMase has not been studied in CHF detail. aim present study characterize activity patients with relation disease severity...
Cerebrospinal fluid (CSF) dynamics in the spinal subarachnoid space (SSS) have been thought to play an important pathophysiological role syringomyelia, Chiari I malformation (CM), and a intrathecal drug delivery. Yet, impact that fine anatomical structures, including nerve roots denticulate ligaments (NRDL), on SSS CSF is not clear. In present study we assessed of NRDL cervical SSS. The 3D geometry was reconstructed based manual segmentation MRI images healthy volunteer patient with CM....
Background:The purpose of the present study was to investigate diagnostic value T2-mapping in acute myocarditis (ACM) and define cut-off values for edema detection.Methods: Cardiovascular magnetic resonance (CMR) data 31 patients with ACM were retrospectively analyzed.30 healthy volunteers (HV) served as a control.Additionally routine CMR protocol, acquired at 1.5 T using breathhold Gradient-Spin-Echo sequence six short axis slices.T2-maps segmented according 16-segments AHA-model segmental...
The aim of this study was the evaluation a fast Gradient Spin Echo Technique (GraSE) for cardiac T2-mapping, combining robust estimation T2 relaxation times with short acquisition times. sequence compared against two previously introduced T2-mapping techniques in phantom and vivo.
Diagnosing myocarditis relies on multimodal data, including cardiovascular magnetic resonance (CMR), clinical symptoms, and blood values. The correct interpretation integration of CMR findings require radiological expertise knowledge. We aimed to investigate the performance Generative Pre-trained Transformer 4 (GPT-4), a large language model, for report-based medical decision-making in context cardiac MRI suspected myocarditis.
Rationale and objectivesCoronary computed tomography angiography (CCTA) is becoming increasingly important for the diagnostic workup of coronary artery disease, nevertheless, imaging in-stent stenosis remains challenging. For first time, spectral in Ultra High Resolution (UHR) now possible clinically available photon counting CT. The aim this work to determine optimal virtual monoenergetic image (VMI) stenoses cardiac stents.Materials methods6 stents with inserted hypodense were scanned an...
The aim of this study was to evaluate the diagnostic potential a novel cardiovascular magnetic resonance (CMR) based multiparametric imaging approach in suspected myocarditis and compare it traditional Lake Louise criteria (LLC).