A5064311851- Animal Behavior and Welfare Studies
- Veterinary Equine Medical Research
- Effects of Environmental Stressors on Livestock
- Animal health and immunology
- Asthma and respiratory diseases
- Microbial infections and disease research
- Animal Disease Management and Epidemiology
- Reproductive Physiology in Livestock
- Genetic and phenotypic traits in livestock
- Animal Virus Infections Studies
- Biosensors and Analytical Detection
- Allergic Rhinitis and Sensitization
- Identification and Quantification in Food
- Viral gastroenteritis research and epidemiology
- Agriculture and Farm Safety
- Human-Animal Interaction Studies
- Salmonella and Campylobacter epidemiology
- Ruminant Nutrition and Digestive Physiology
- Veterinary Pharmacology and Anesthesia
- Inflammatory mediators and NSAID effects
- Veterinary Oncology Research
- Listeria monocytogenes in Food Safety
- Exercise and Physiological Responses
- Image Processing Techniques and Applications
- Bacteriophages and microbial interactions
University of Copenhagen
2014-2025
Aarhus University
2019-2023
Danish Medicines Agency
2023
John Wiley & Sons (United States)
2023
Hudson Institute
2023
Animal Welfare Institute
2014
3M (United States)
2001-2002
Bellevue Hospital Center
2000
German Cancer Research Center
1994
Federal Roads Office
1994
Structural development in the prime sector has led to increasing herd sizes and new barn systems, followed by less summer grazing for dairy cows Denmark. Effects of on single welfare measures – example, presence integument alterations or mortality have been studied under different conditions. However, effect welfare, conceptualised as multidimensional physical mental state animal, not yet contemporary cubicle loose-housing systems. The aim our study was investigate, based a Welfare Quality®...
The contribution of redox imbalance to equine asthma (EA) pathogenesis remains unclear. (1) validate and measure a panel biomarkers in the tracheal wash (TW) bronchoalveolar lavage (BAL) samples from horses with neutrophilic mastocytic mild-moderate EA (MEA) severe EA. (2) Evaluate same saliva serum for comparative purposes. A total 117 horses: 37 healthy, 26 MEA, 29 25 Cross-sectional study using TW, BAL, sampling. After assay validation, biomarkers-ferric reducing antioxidant power (FRAP),...
Calves are born agammaglobulinemic and depend on transfer of passive immunity from colostrum. Failure (FTPI) adequate (ATPI) defined as serum immunoglobulin G (IgG) levels < 10 ≥ mg/mL, respectively. The objective this study was to evaluate the level passively transferred in Danish dairy calves measured with Enzyme-linked immunosorbent assay (ELISA) Brix refractometer. Blood samples 834 (430 bull 404 heifer calves) aged two nine days were included study. Serum IgG concentration determined by...
Influenza D virus (IDV) was first described in 2011 and has been found to mainly circulate among cattle swine populations worldwide. Nasal swab samples were collected from 100 Danish calf herds (83 dairy 17 veal herds) 2018–2020. detected 12 of the herds. Samples with lowest cycle quantification value selected for full genome sequencing. A hemagglutinin-esterase fusion (HEF) gene sequence a IDV 2015 also included this study. Phylogenetic analysis showed that viruses seven IDV-positive...
Abstract Background Bronchoalveolar lavage (BAL) cytology results from 1 lung might not be representative of both lungs. Objectives To determine whether the site sampled would influence horse's BAL profile, and if a pooled sample superior with regard to diagnosis in cohort healthy subclinical asthmatic warmblood horses. Animals Fifty‐nine horses 2021 70 2022, follow‐up included 53 same each year. Methods A cross‐sectional study samples individual lungs samples. The were enumerated...
This study aimed to enhance our understanding of the agreement between two sampling methods for detection bovine respiratory disease (BRD) pathogens in calves using high-throughput real-time qPCR (ht-RT-qPCR). In total, 233 paired nasal swab (NS) and non-endoscopic bronchoalveolar lavage (nBAL) samples were collected from 152 12 Danish cattle herds. 202 observations, examined a standardized clinical protocol. Samples tested three viruses (bovine syncytial virus, corona influenza D virus) six...
The assessment of animal welfare can include resource-based or animal-based measures. Official inspections in Denmark primarily control compliance with legislation based on resource measures (e.g. housing system) and usually do not regard response parameters clinical behavioural observations). Herds selected for are sampled by a risk-based strategy existing register data. aim the present study was to evaluate data variables as predictors dairy herds violations (VoAWL) defined occurrence at...
Assessing emotional states of dairy calves is an essential part welfare assessment, but standardized protocols are absent. The present study aims at assessing the and establishing a reliable standard procedure with Qualitative Behavioral Assessment (QBA) 20 defined terms. Video material was used to compare multiple observer results. Further, live observations were performed on 49 herds in Denmark Italy. Principal Component Analysis (PCA) identified agreement QBA dimensions (PC). For...
Rearing replacement heifers is pivotal for the dairy industry and associated with high input costs preweaned calves, due to their higher susceptibility diseases. Ensuring calf health viability calls systematic approaches in order mitigate induced by managing sick calves ensure animal welfare. The objective of this study was develop a feasible health-monitoring tool bovine based on repeated clinical observations diagnostic results at three time points; 1st (T0), 3rd (T1) 12th (T3) week age....
Bovine respiratory disease (BRD) results from interactions between pathogens, environmental stressors, and host factors. Obtaining a diagnosis of the causal pathogens is challenging but use high-throughput real-time PCR (rtPCR) may help target preventive therapeutic interventions. The aim this study was to improve interpretation rtPCR by analysing their associations with clinical observations. objective develop illustrate field-data driven statistical method guide selection relevant...
Summary A xanthate compound with antiviral and antitumoural activities, tricyclodecan‐9‐yl‐xanthogenate (D609) in combination the potassium salt of lauric acid (KC 12 ) and, a further investigation, above‐mentioned substances together recombinant human TNFα‐(rh‐TNFα), were tested on equine sarcoid tumours for therapeutic efficacy. pilot investigation 5 healthy horses showed that compounds well‐tolerated; apart from local, temporary oedema at injection site, no other clinical symptoms...
The 3M Petrifilm Staph Express Count plate method was compared with AOAC Official Method 975.55 for the enumeration of Staphylococcus aureus in selected foods. Five foods--ice cream, raw milk, yogurt, whey powder, and cheese--were analyzed S. by 12 collaborating laboratories. For each food tested, collaborators received 8 blind test samples consisting a control sample, low inoculation level, medium level background flora, duplicate. mean log10 counts methods were comparable all 5...
Control of infectious diseases in livestock has often been motivated by food safety concerns and the economic impact on production. However, may also affect animal welfare. We present an approach to quantify effect five welfare cattle (three diseases) pigs (two diseases). grouped clinical manifestations that occur together into lists entities for each disease based literature reviews, subsequently estimated "suffering scores" aggregation duration, frequency, severity. The duration severity...
A rehydratable dry-film plating method for coliforms in foods, the 3M Petrifilm Rapid Coliform Count plate method, was compared with U.S. Food and Drug Administration's Bacteriological Analytical Manual nondairy foods American Public Health Association's Standard Methods Examination of Dairy Products (SMEDP) dairy foods. Six food types, vanilla ice cream, cheddar cheese, fresh refrigerated uncooked pasta, wheat flour, prepared frozen macaroni hash browns, were analyzed by 11 collaborating...
The present study seeks to investigate the influence of expert affiliation in weighing procedures within animal welfare assessments. Experts are often gathered with different backgrounds differing approaches posing a potential pitfall if groups not balanced numbers experts. At two time points (2012 and 2016), dairy cattle swine experts from four stakeholder groups, namely researchers (RES), production advisors (CONS), practicing veterinarians (VET) control officers (AWC) were asked weigh...
Abstract Background The modern dairy industry routinely generates data on production and disease. Therefore, the use of these cheap at times even “free” to predict a given state welfare in cost-effective manner is evaluated present study. Such register could potentially be used identification herds risk having animal problems. study diagnostic performance four registered indicators for identifying with high lameness prevalence among 40 Danish herds. Indicators were extracted as within-herd...
Studies in people have found neutrophil gelatinase-associated lipocalin (NGAL) concentrations are increased asthma and can be used to distinguish between subtypes. NGAL has not yet been investigated equine (EA).To investigate the ability of bronchoalveolar lavage (BAL) fluid serum control horses, horses with mild-moderate EA (MEA) severe (SEA).Retrospective cross-sectional study.Details endoscopic examination including tracheal mucus score (TMS, scale 0-5) BAL cytology performed on 227 were...
Background: Endoscopy, including tracheal mucus score (TMS) and bronchoalveolar lavage (BAL) fluid cytology, are commonly used to diagnose equine asthma (EA). Large-scale studies comparing clinical signs, TMS BAL cytology warranted. Objectives: Investigate associations between signs of EA, cytology. Study design: cross-sectional study Methods: Data from 604 horses, each horse having one sample evaluated at the laboratory service Large Animal Teaching Hospital in Denmark, with further...
Abstract Background Atrial fibrillation (AF) has been proposed as a risk factor for exercise‐induced pulmonary haemorrhage (EIPH) due to increased pressure in the left atrium. Objective To evaluate if AF was associated with EIPH following standardised exercise test (SET) fatigue. Study design Two‐arm controlled experiment. Methods Ten untrained Standardbred mares mean (standard deviation [SD]) age 6 (2) years performed SET on treadmill sinus rhythm (SR) (SET1) and 25–44 days after induction...