A5063699440- Blood Pressure and Hypertension Studies
- Antioxidant Activity and Oxidative Stress
- Cardiovascular Health and Disease Prevention
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Phytochemicals and Antioxidant Activities
- Nutritional Studies and Diet
- COVID-19 and healthcare impacts
- Long-Term Effects of COVID-19
- Natural Antidiabetic Agents Studies
- Gout, Hyperuricemia, Uric Acid
- Sodium Intake and Health
- Cerebrovascular and Carotid Artery Diseases
- Diet and metabolism studies
- Tea Polyphenols and Effects
- Fatty Acid Research and Health
- Lipoproteins and Cardiovascular Health
- Climate Change and Health Impacts
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Atherosclerosis and Cardiovascular Diseases
- Liver Disease Diagnosis and Treatment
- Pomegranate: compositions and health benefits
- Nitric Oxide and Endothelin Effects
University of L'Aquila
2015-2024
University of Siena
2023
University of Padua
2023
Ospedale Regionale di Mendrisio
2023
San Salvatore Hospital
2012-2022
Health & Life (Taiwan)
2022
Sapienza University of Rome
2007-2021
Istituto Neurologico Mediterraneo
2021
University of Udine
2020
University of Perugia
2020
Consumption of flavanol-rich dark chocolate (DC) has been shown to decrease blood pressure (BP) and insulin resistance in healthy subjects, suggesting similar benefits patients with essential hypertension (EH). Therefore, we tested the effect DC on 24-hour ambulatory BP, flow-mediated dilation (FMD), oral glucose tolerance tests (OGTTs) EH. After a 7-day chocolate-free run-in phase, 20 never-treated, grade I EH (10 males; 43.7±7.8 years) were randomized receive either 100 g per day...
Several factors have been proposed to explain the high death rate of coronavirus disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related treatment with Renin Angiotensin System inhibitors. Also, age multimorbidity might be confounders. No sufficient data are available demonstrate their independent role. We designed a cross-sectional, observational, multicenter, nationwide survey in Italy verify whether renin-angiotensin system inhibitors related COVID-19 severe...
Flavanol consumption is favorably associated with cognitive function. We tested the hypothesis that dietary flavanols might improve function in subjects mild impairment. conducted a double-blind, parallel arm study 90 elderly individuals impairment randomized to consume once daily for 8 weeks drink containing ≈990 mg (high flavanols), ≈520 (intermediate or ≈45 (low flavanols) of cocoa per day. Cognitive was assessed by Mini Mental State Examination, Trail Making Test A and B, verbal fluency...
Background: Cocoa flavonoids exert beneficial vascular effects and reduce the risk of cardiovascular morbidity mortality. Nevertheless, involved mechanisms have not been clarified no study has yet focused on dose–response effects. Objectives: We aimed to investigate different doses cocoa flow-mediated dilation (FMD), endothelin-1 (ET-1), pulse wave velocity (PWV), SBP DBP. Design: According a randomized, double-blind, controlled, cross-over design, 20 healthy volunteers (1.5% improvement in...
Abstract The coronavirus 2019 disease (COVID-19) is characterised by a heterogeneous clinical presentation, complex pathophysiology and wide range of imaging findings, depending on severity time course. We conducted retrospective evaluation hospitalized patients with proven SARS-CoV-2 infection, signs COVID-19 computed tomography (CT) scan-proven pulmonary involvement, in order to identify relationships between clinical, serological, data outcomes COVID-19. Clinical serological records...
Flavonoids may protect against cardiovascular disease. Tea is a major source of dietary flavonoids. Studies indicate black tea improves endothelial function but data on arterial haemodynamics, blood pressure (BP) and insulin resistance are equivocal. Inconsistency be due to flaws in study design or flavonoid doses tested. Further, no has evaluated the dose-response curve. Our aimed test effects various vascular function, BP resistance.According randomized, double-blind, controlled,...
Nitric oxide plays a pivotal role in regulating vascular tone. Different studies show endothelial function is impaired during hyperglycemia. Dark chocolate increases flow-mediated dilation healthy and hypertensive subjects with without glucose intolerance; however, the effect of pretreatment dark on other responses to hyperglycemia has not been examined. Therefore, we aimed investigate effects flavanol-rich administration (1) wave reflections; (2) blood pressure, endothelin-1 oxidative...
Background The global rate of intensive care unit (ICU) admission during the COVID-19 pandemic varies within countries and is among main challenges for health systems worldwide. Conflicting results have been reported about response to coronavirus infection outcomes in men women. Understanding predictors might be help future planning management disease. Methods findings We designed a cross-sectional observational multicenter nationwide survey Italy understand gender-related clinical ICU...
During the COVID-19 2020 outbreak, a large body of data has been provided on general management and outcomes hospitalized patients. Yet, relatively little is known characteristics outcome patients managed in Internal Medicine Units (IMU). To address this gap, Italian Society conducted nationwide cohort multicentre study death adult admitted IMU. This assessed 3044 at 41 referral hospitals across Italy from February 3rd to May 8th 2020. Demographics, comorbidities, organ dysfunction,...