A5101800872- Gastric Cancer Management and Outcomes
- Esophageal Cancer Research and Treatment
- Lung Cancer Treatments and Mutations
- Cancer-related Molecular Pathways
- Ubiquitin and proteasome pathways
- Mass Spectrometry Techniques and Applications
- Advanced Proteomics Techniques and Applications
- Nutrition and Health in Aging
- Computational Drug Discovery Methods
- Analytical Chemistry and Chromatography
- Total Knee Arthroplasty Outcomes
- Nerve injury and regeneration
- Sexual function and dysfunction studies
- Metastasis and carcinoma case studies
- Gastrointestinal disorders and treatments
- Neurogenesis and neuroplasticity mechanisms
- Vascular Malformations and Hemangiomas
- Lymphatic Disorders and Treatments
- Cervical Cancer and HPV Research
- Radiopharmaceutical Chemistry and Applications
- Vitamin K Research Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Enhanced Recovery After Surgery
- Abdominal Trauma and Injuries
- Autoimmune and Inflammatory Disorders
Yuhuangding Hospital
2016-2025
Qingdao University
2016-2025
Shandong Provincial QianFoShan Hospital
2023-2024
Shandong First Medical University
2023-2024
Cargill (United Kingdom)
2024
Guangdong Pharmaceutical University
2023
First Affiliated Hospital of Guangdong Pharmaceutical University
2022-2023
Third Affiliated Hospital of Sun Yat-sen University
2020-2023
Sun Yat-sen University
2020-2023
Guangdong 999 Brain Hospital
2020-2022
We report a miniaturized filter aided sample preparation method (micro-FASP) for low-loss of submicrogram proteomic samples. The employs with ∼0.1 mm2 surface area, reduces the total volume reagents to <10 μL, and requires only two transfer steps. was used generate 25 883 unique peptides 3069 protein groups from 1000 MCF-7 cells (∼100 ng content), 13 367 1895 were identified 100 (∼10 content). Single blastomeres Xenopus laevis embryos at 50-cell stage (∼200 yolk free protein/blastomere)...
Patients with gastrointestinal surgery have a higher incidence of infection-related complications than the rest those who undergo clean cut surgery. It can lead to worse prognosis for patients. This study aimed assess association between glycemic variability (GV) and postoperative cancer A total 438 patients were included in this study. Using univariate multivariate regression analyses, risk factors determined. And nomogram prediction models constructed through machine learning. The...
1. Schimmack S, Svejda B, Lawrence Kidd M, Modlin IM. (2011). The diversity and commonalities of gastroenteropancreatic neuroendocrine tumors Langenbecks Arch Surg. 396: 273-98. Google Scholar
Growth differentiation factor 15 (GDF15) is a divergent member of the transforming growth factor-β (TGF-β) superfamily that has been associated with colorectal cancers (CRC). However, role GDF15 in progression CRC remains unknown. We demonstrated expression was higher fresh tissues than adjacent normal tissues. Moreover, we found overexpression significantly facilitated cell viability, invasion and migration (p < .01 or p .05). The protein N-cadherin, vimentin Twist1 were up-regulated by...
Abstract Objective: To compare the numbers of positive and total lymph nodes prognosis in gastric cancer patients whose perigastric node retrieval was performed by surgeons pathologists. Methods: We conducted a retrospective analysis clinical follow-up data from 1, 056 who underwent D2 radical resection between January 2008 December 2010 Gastrointestinal Surgery Department Yantai Yuhuangding Hospital. The ended 2015. Patients were divided into two groups according to specialty physicians...
Erectile dysfunction (ED) often occurs due to cavernous nerve injury (CNI) after colorectal surgery. Cell-based therapies have great potential for the treatment of CNI-related ED; however, it needs be optimised. In this study, we explored therapeutic effects lipopolysaccharide-preconditioned allogeneic adipose-derived stem cells (L-ADSCs) on CNI-induced ED in rats. The results vitro study revealed that low-dose lipopolysaccharide could increase viability ADSCs, inhibit caspase 3 activation...
Objective To investigate the influencing factors of functional recovery after high tibial osteotomy (HTO). Methods A retrospective research was carried on 98 patients who underwent HTO between January 2018 and December 2020. In each case, medial proximal angle (MPTA), joint line convergence (JLCA), femoral (FTA), hip-knee-ankle (HKA), weight bearing (WBL) ratio knee joint, opening gap, angle, American society score (KSS), US Hospital for Special Surgery (HSS) score, Lysholm Western Ontario...
This case describes the benefits of perioperative chemo-immunotherapy for advanced gastric cancer and incomplete pyloric obstruction, supplemented with nutritional support. Early parenteral nutrition to stabilize status mitigate impact symptoms, in addition, throughout period also maintained oral support a tailored dietary plan. Above patient’s physical condition during immunotherapy. Eventually, this combination therapy plan leads partial response. On other hand, therapies that focus more...
The <italic>Xenopus laevis N</italic>-glycome undergoes massive reprogramming after the midblastula transition and onset of neuronal development.
Abstract Purpose Platinum-based chemotherapy remains a standard-of-care for most patients with advanced non-small cell lung cancer (NSCLC). DNA damage response (DDR) induced by platinum or Etoposide activated panel of cycle-regulatory proteins including p21 through p53 pathway. Previous studies have reported that RanBPM has been involved in various cellular processes such as DDR interacting multiple proteins. However, the underlying mechanism unclear. Methods NSCLC tissue microarrays were...
This study was conducted to investigate the therapeutic potential of skin-derived precursor Schwann cells for treatment erectile dysfunction in a rat model bilateral cavernous nerve injury. The cells-treatment significantly restored functions, accelerated recovery endothelial and smooth muscle tissues penis, promoted repair. expression p-Smad2/3 decreased after treatment, which indicated reduced fibrosis corpus cavernosum. Implantation is an effective strategy treating induced by
Abstract Non-small cell lung cancer (NSCLC) is the leading cause of cancer-induced deaths around world, and platinum-based chemotherapy remains a standard-of-care for most patients with advanced NSCLC. DNA damage response (DDR) induced by platinum or Etoposide activated panel cycle-regulatory proteins including p21 through p53 pathway. In this present study, we found that level RanBPM lower in NSCLC than non-malignant tissues has highly positive correlation, which positively correlated...
Objective To investigate the early effect of high tibial osteotomy (HTO) compared with combined arthroscopic surgery. Methods A retrospective study was conducted on patients who underwent HTO at The First Affiliated Hospital Shandong Medical University from January 2018 to 2022. 138 (163 knees) knee osteoarthritis (KOA) treated were selected. medial proximal angle (MPTA), joint line convergence (JLCA), femoral (FTA), hip-knee-ankle (HKA) angle, weight-bearing (WBL) ratio joint, opening gap,...