Lea Pogačnik

ORCID: 0000-0003-1008-0633
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Antioxidant Activity and Oxidative Stress
  • Electrochemical sensors and biosensors
  • Electrochemical Analysis and Applications
  • Biological Activity of Diterpenoids and Biflavonoids
  • Medicinal Plants and Bioactive Compounds
  • Parkinson's Disease Mechanisms and Treatments
  • Plant and fungal interactions
  • Phytochemistry and Biological Activities
  • Advanced Chemical Sensor Technologies
  • Pomegranate: compositions and health benefits
  • Garlic and Onion Studies
  • Alzheimer's disease research and treatments
  • Essential Oils and Antimicrobial Activity
  • Various Chemistry Research Topics
  • Cholinesterase and Neurodegenerative Diseases
  • Pesticide Exposure and Toxicity
  • Ginkgo biloba and Cashew Applications
  • Biochemical Acid Research Studies
  • Bee Products Chemical Analysis
  • Fungal Biology and Applications
  • Curcumin's Biomedical Applications
  • Natural Antidiabetic Agents Studies
  • Analytical chemistry methods development
  • Allelopathy and phytotoxic interactions

University of Ljubljana
2003-2024

Ridge Lea Hospital
2017

University of Lisbon
2017

School Centre Nova Gorica
2001-2003

Jožef Stefan Institute
1999

There is increasing concern for reduction of the ecological impacts industrial waste caused by fruits and vegetables. To reduce costs onion disposal while obtaining value-added products, skin can be used to extract quercetin, a natural flavonoid with antioxidant, anti-inflammatory anti-cancer effects. The aim was optimize quercetin extraction from brown (Allium cepa L.) through investigation effects different parameters on yield. Operational conventional maceration ultrasound-assisted were...

10.3390/ijms21082909 article EN International Journal of Molecular Sciences 2020-04-21

Lactic acid fermentation (LAF) is known to improve nutritional properties and functionality extend the shelf life of foods. We studied LAF Arthrospira platensis as sole substrate using Lactobacillus plantarum starter culture. Fermented (FB) non-fermented broth (NFB) were analysed by means pH, lactic bacteria (LAB) count, concentration, microbiological safety, composition. Additionally, water ethanol extracts prepared on which total phenolic content, DPPH radical scavenging activity, cellular...

10.3390/antiox11020216 article EN cc-by Antioxidants 2022-01-23

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHow To Motivate Students Study before They Enter the LabLea Pogacnik and Blaz Cigic View Author Information Department of Food Science Technology, Biotechnical Faculty, University Ljubljana, Jamnikarjeva 101, 1000 SloveniaCite this: J. Chem. Educ. 2006, 83, 7, 1094Publication Date (Web):July 1, 2006Publication History Received3 August 2009Published online1 July 2006Published inissue 1...

10.1021/ed083p1094 article EN Journal of Chemical Education 2006-07-01

Neuron loss and neurodegeneration are the common denominators of what known as neurodegenerative diseases. Although clinical manifestations some diseases mainly associated with ageing, it is believed that onset disease neuronal death occurs progressively through life, well before first symptoms appear. So, one main dilemmas regarding therapies treatment often starts long after has occurred, when a great number neurons have already been lost. Furthermore, little information available about...

10.4103/1673-5374.205096 article EN cc-by-nc-sa Neural Regeneration Research 2017-01-01

Knotweed is a flowering plant that native to temperate and subtropical regions in the northern hemisphere. We evaluated Japanese (Reynoutriajaponica Houtt.) Bohemian (Fallopiaxbohemica) knotweed rhizome flower ethanol extracts compared them terms of their biological activities. The specific polyphenols were identified quantified using HPLC/DAD, antioxidant activity was determined 2,2-diphenly-1-picrylhydrazyl (DPPH) cellular capacity assays. anticancer as difference between cytotoxicity...

10.3390/foods9050544 article EN cc-by Foods 2020-04-30

ABSTRACT A chemiluminescence (CL) assay for the determination of antioxidant capacity (AOC) has been optimized and applied to analyses herbal extracts in present study. The optimal concentrations reagents (luminol, H 2 O , horseradish peroxidase) have determined, as well reaction conditions (wavelength, pH, temperature, sample volume). All measurements were performed at emission maximum oxidized form luminol (425 nm). determined follows: 1.6 mmol/L luminol, 7.5 0.14 U/mL peroxidase activity...

10.1002/bio.1384 article EN Luminescence 2012-01-30

Aggregation of the intrinsically disordered protein α-synuclein into ordered amyloid fibrils is implicated in pathogenesis Parkinson’s disease. To unravel role Tyr residues fibrillation, we prepared recombinant N-terminal (Y39A) and C-terminal (Y(125,133,136)A) mutants examined their fibrillation propensities by thioflavin T 1-anilinonaphthalene-8-sulfonate (ANS) fluorescent probes, SDS-PAGE atomic force microscopy. We demonstrate that contrast to wild-type α-synuclein, both show large, but...

10.17344/acsi.2014.882 article EN cc-by Acta chimica slovenica 2015-03-15

Knotweed is an invasive plant that creates high compact growth when uncontrolled can suppress the of native plants and thus reduce biological diversity. These contain many antioxidants require identification quantification. In this work, aqueous 2% acetic acid, 50% ethanol in pure butanol extracts young leaves, old rhizomes, stalks, flowers from three European knotweed species Fallopia japonica, sachalinensis, × bohemica were prepared analyzed for their antioxidant capacities. Four methods...

10.1080/00032719.2014.979361 article EN Analytical Letters 2015-04-11

Abstract Laser-induced photo-oxidation of organophosphorus compounds in aqueous media and the applicability an acetylcholinesterase based bioanalytical method for evaluation organohosphate's toxicity has been investigated. Rapid decomposition achieved within two hours following irradiation range concentrations, limited by solubility pesticide (up to 40 mgL−1). The detected irradiated samples suggest that diazinon is converted directly into 2-isopropyl-4-methyl-6-hydroxypyrimidine without...

10.1080/714037678 article EN Critical Reviews in Analytical Chemistry 2003-10-01

Mushrooms have been an important part of the diet for centuries. There are more than 2,000 different species mushrooms found in nature, but only 25 generally used human diet, and even fewer grown commercially. One popular cultivation culinary use genus Pleurotus . The objectives this study were: (i) preparation isolates from basidiomycetes ostreatus by sequential extraction with cold hot water, water alkali solution determination antiradical activity (ii) 70% ethanol extracts antidiabetic...

10.1051/e3sconf/202021505006 article EN cc-by E3S Web of Conferences 2020-01-01

Polyphenols are a group of secondary metabolites found in wide variety foods, such as fruits, vegetables, wine, tea, olive oil and chocolate. These compounds, addition to their antioxidant activity, also possess strong anti-inflammatory properties. Numerous studies have therefore confirmed potential role preventing treating various pathological conditions associated with oxidative stress inflammation. Among these, the most prevalent ones include cancer, cardiovascular neurodegenerative...

10.14720/aas.2020.115.2.1472 article EN cc-by Acta agriculturae Slovenica 2020-06-18
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