Low-shear viscometry is one of the methods commonly used to estimate degree red blood cell (RBC) aggregation in various bloods and RBC suspensions. However, it has been previously shown that alterations morphology mechanical behavior can affect low-shear apparent viscosity suspensions; also sensitive these cellular factors. This study heat treatment (48°C, 5 min), glutaraldehyde (0.005–0.02%) hydrogen peroxide (1 mM) modify geometry deformability. Red was assessed via a Myrenne Aggregometer...

Background Developmental venous anomalies (DVAs) are benign anatomical variations in angioarchitecture. They considered low-flow malformations and often incidental clinically insignificant. Hemorrhagic complications from isolated DVAs extremely rare, typically occurring due to coexisting cavernous malformation. Case Description A 33-year-old female presented with severe headaches vertigo, progressing balance issues dizziness. Misdiagnosed initially as Meniere’s disease, her symptoms included...

Abstract Objectives and Background Chronic subdural hematoma (CSDH) is characterized by the develeopment of a membranous following mild to moderate head trauma, with its pathophysiology involving posttraumatic inflammatory processes. The aim our study was investigate relationship between peripheral blood cell markers various clinical radiological parameters in CSDH patients under 65 years. Methods We conducted retrospective analysis 53 diagnosed unilateral who underwent surgical intervention...

Red blood cell (RBC) shape change under shear is generally reversible, with the time course of recovery a function elastic and viscous properties RBC membrane. can be investigated, using several different techniques, to provide information about membrane material that are not directly accessible by frequently used methods assess deformability (e.g., micropore filtration). In present study, was studied in Couette system after abrupt cessation shear, either analyzing laser light reflection or...

Diffuse axonal injury (DAI), one of the most common and devastating type traumatic brain injury, is result shear force on axons due to severe rotational acceleration deceleration. Neurogranin (NRGN) a postsynaptic protein secreted by excitatory neurons, synaptic dysfunction can alter extracellular NRGN levels. In this study, we examined levels in serum cerebrospinal fluid (CSF) after experimental DAI terms their diagnostic value. Experimental was induced using Marmarou technique male Wistar...

Purpose: Today, stereotactic surgery (SRS) is among the treatment options for many intracranial lesions including vascular pathologies. One of most common late complications SRS perilesional edema which can be treated with steroids. In addition to steroids, some new medical therapies are being investigated and one promising Bevacizumab; a monoclonal antibody against endothelial growth factor (VEGF). cases steroid resistant edemas, however bevacizumab has term effect resolution symptoms...

A 34-year-old male patient with decreased libido, visual disturbance, and intermittent severe headache was referred to our Pituitary Center.Endocrinological evaluation at presentation revealed panhypopituitarism hyperprolactinemia (Table 1).Despite appropriate hormone replacement therapy, his symptoms persisted.Ophthalmologic examination acuity, right temporal hemianopsia, bilateral pallor of the optic disk.Pituitary magnetic resonance imaging (MRI) showed a thickening in upper half...

Abstract Background Glioblastomas are the most common and highly malignant primary brain tumors in adults with a median survival of 15 months even appropriate treatment. Extracranial metastases extremely rare due to poor prognosis not allowing sufficient time spread. We report an case extracranial metastasis supra-tentorial glioblastoma involving skin, subcutaneous muscular layers, periauricular region parotid gland, review literature. A total 13 gland cases have been hitherto described....

Abstract Background Fahr’s disease is a very rare inherited neurodegenerative disorder characterized by diffuse and symetric intracranial calcification of the bilateral basal ganglia cerebellum. Although slowly progressive, several acute forms have been described. We would like to present case with an ischemic stroke its hemorrhagic transformation. Case presentation A 70-year-old woman presented our emergency department rapid cognitive decline, dysarthria right limb weakness. Cranial...

Abstract Introduction Diagnosis of the origin ACTH-dependent Cushing's syndrome (CS) can be difficult in some cases, especially when MRI pituitary gland does not reveal an adenoma. Inferior petrosal (IPSS) or cavernous sinus sampling (CSS) with CRH stimulation helps confirm central most cases. CSS also lateralize tumor within a sensitivity 80%. Because transsphenoidal surgery is successful majority MRI-negative bilateral adrenalectomy performed less frequently. Even advanced radiologic...

Abstract Introduction Silent corticotroph adenomas (pituitary neuroendocrine tumours (PitNET)) are a rare subset of nonfunctioning adenomas. The higher aggressiveness in terms invasion and recurrence make these tumors dangerous close follow-up experienced centers is recommended. Clinical Case A 21-year-old obeseo (Body Mass Index:31.71) male patient unable to lose weight complaining headaches was referred the Department Neurosurgery for pituitary macroadenoma. He had previously used...

Abstract Multisutural synostosis, characterized by the fusion of multiple cranial sutures without a clear underlying syndrome, represents rare subtype craniosynostosis. Particularly uncommon is simultaneous sagittal, metopic, and bilateral coronal sutures. This report details case 50-month-old boy, previously healthy, who has displayed an abnormal head shape since infancy due to complex, non-syndromic craniosynostosis involving four The closure led distinct marked flattening forehead...

Idiopathic intracranial hypertension or pseudotumor cerebri is defined as increased pressure without radiologic findings of masses obstructive hydrocephalus.Typical symptoms include headache, nausea, visual disturbances, and papilledema.In some cases, radiculopathy may present acral paresthesias, back pain, radicular pain.We here an extremely rare case sensorimotor caused by idiopathic hypertension; manifested drop foot treated with cerebrospinal fluid diversion.

A BSTRACT Tethered cord syndrome is a neurological disorder closely associated with congenital spinal dysraphism. Aberrant dorsal nerve roots may be one of the possible and relatively rare tethering pathologies, especially in complex form occult dysraphism such as caudal regression or split malformation. We report an illustrative case due to combination contiguous bundle aberrant root, dorsal-type lipomyelomeningocele, thickened filum terminale treated microneurosurgical untethering.

Intracranial solitary fibrous tumors (SFTs) and hemangiopericytomas (HPCs) are rare, aggressive typically found along the dural sinuses. Despite their nature, complete surgical resection remains most significant factor in reducing recurrence improving survival. Here, we present case of a 32-year-old male patient who presented with new-onset headache vertigo. Magnetic resonance imaging revealed 50×37 mm left occipital mass originating from falx extending into tentorium, heterogeneous...

Multisutural synostosis, characterized by the fusion of multiple cranial sutures without a clear underlying syndrome, represents rare subtype craniosynostosis. Particularly uncommon is simultaneous sagittal, metopic, and bilateral coronal sutures. This report details case 50-month-old boy, who had an abnormal head shape due to four The closure has led distinct marked flattening forehead anterior skull, contrasting with typical Mercedes-Benz pattern observed in craniosynostosis cases....

We present a rare case of traumatic pneumorrhachis with the combination hemothorax which resolved rapidly after insertion chest tube.A 55 year old male was admitted to our emergency department falling from ladder. His general condition well, GCS 15 no motor deficits. On his spinal CT fracture on multiple ribs leading right sided observed air in T6-T8 canal. A tube placed and as he did not have any neurological deficits surgical intervention considered. next day's follow-up canal reduced 5th...

Introduction There is considerable uncertainty about the reproducibility of various instruments used to measure dyspnea, their ability reflect changes in symptoms, whether they accurately patient's experience and if its evolution similar between acute heart failure syndrome patients nonacute patients.URGENT was a prospective multicenter trial designed address these issues.Methods Patients were interviewed within 1 hour first physician evaluation, emergency department or care setting, with...

To detect the silent pulmonary thromboembolism (SPTE) frequency in patients who underwent craniotomy for a brain tumor, and to examine correlation based on data obtained from patients.Overall, 100 with tumors were included study. The mean age was 54.29 years (±12.5 years), youngest patient being 19 old oldest 73 years. All craniotomy, ventilation-perfusion scintigraphy performed 48 h after surgery SPTE. of SPTE conditions related it investigated.The incidence 26% tumor craniotomy....