A5017648243- Microbial infections and disease research
- Animal health and immunology
- Clostridium difficile and Clostridium perfringens research
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Effects of Environmental Stressors on Livestock
- Veterinary Equine Medical Research
- Aquaculture disease management and microbiota
- Bacterial Identification and Susceptibility Testing
- Toxin Mechanisms and Immunotoxins
- Mycobacterium research and diagnosis
- Respiratory viral infections research
- Veterinary medicine and infectious diseases
- Bacteriophages and microbial interactions
- Viral Infections and Vectors
- Milk Quality and Mastitis in Dairy Cows
- Animal Behavior and Welfare Studies
- Reproductive Physiology in Livestock
- Infectious Diseases and Mycology
- Animal Virus Infections Studies
- Ruminant Nutrition and Digestive Physiology
- Helminth infection and control
- Plant and fungal interactions
Ghent University
2016-2025
Ghent University Hospital
2010-2023
University of Bern
2016
Utrecht University
2015
Geneeskundige en Gezondheidsdienst
2014
Heinrich Heine University Düsseldorf
1994
To document and quantify drug use in white veal calves, an intensive livestock production system where multidrug resistance is abundantly present. Drug consumption data were prospectively collected on 15 cohorts (n = 5853 calves) Belgium (2007–09). Treatment incidences (TIs) based animal defined daily dose (ADD), prescribed (PDD) used (UDD) calculated. Risk factors identified by linear regression. The average TIADD of antimicrobial treatments was 416.8 ADD per 1000 animals at risk....
Mortality and morbidity are hardly documented in the white veal industry, despite high levels of antimicrobial drug use resistance. The objective present study was to determine causes epidemiology mortality dairy, beef crossbred production. A total 5853 calves, housed 15 production cohorts, were followed during one cycle. Causes determined by necropsy. Morbidity daily recorded producers. risk 5,3% significantly higher compared dairy or crossbreds. main pneumonia (1.3% calves at risk),...
Clostridium difficile is an important cause of intestinal infections in some animal species and animals might be a reservoir for community associated human infections. Here we describe collection C. strains from 12 countries based on inclusion criteria one strain (PCR ribotype) per laboratory. Altogether 112 isolates were collected distributed into 38 PCR ribotypes with agarose approach 50 sequencer approach. Four most prevalent terms number as well different host species: 078 (14.3%...
Little is known on the effects of common calf diseases mortality and carcass traits in white veal industry (special-fed veal), a highly integrated production system, currently criticized for intensive pro- metaphylactic use antimicrobials. The objective present study was to determine impact bovine respiratory disease (BRD), diarrhea, arthritis otitis economically important parameters mortality, hot weight (HCW), quality, fat cover meat color. For this purpose, prospective 3519 calves, housed...
The aim of this study was to investigate the relationship between antimicrobial use and occurrence resistance in digestive respiratory tract three different production systems food producing animals. A longitudinal set up 25 Belgian bovine herds (10 dairy, 10 beef, 5 veal herds) for a 2 year monitoring susceptibilities E. coli Pasteurellaceae retrieved from rectum nasal cavity, respectively. During first observation, prospectively recorded on 15 these farms (5 each type) transformed into...
The prevalence of respiratory pathogens in diseased veal calves was determined 24 disease outbreaks 15 herds Belgium. Bacteria were cultured from nasopharyngeal swabs and seroconversion against viruses Mycoplasma bovis on paired sera. At the individual calf level, species, Mannheimia haemolytica Pasteurella multocida , isolated 70.5 per cent, 21.5 cent 26.0 swabs, respectively. herd presence M could be confirmed 84.6 examined. Seroconversion bovine viral diarrhoea virus (BVDV) present 71.4...
Bovine respiratory disease (BRD) continues to be a leading cause of economic loss, hampered animal welfare, and intensive antimicrobial use in cattle operations worldwide. Reduction is hindered because it still unclear which clinical signs are best monitored reliably detect pneumonia. Also, these may vary according age between breeds. The objective this cross-sectional study was identify associated with ultrasound-confirmed pneumonia (lung consolidation ≥1 cm depth) pre- postweaning...
Abstract Background Sepsis is a life‐threatening condition for which critically important antimicrobials are often indicated. The value of blood culture sepsis indisputable, but appropriate guidelines on sampling and interpretation currently lacking in cattle. Objective Compare the diagnostic accuracy 2 media (pediatric plus [PP] aerobic [PA]) hypoglycemia bacteremia detection. Estimate contamination risk cultures ill calves. Animals One hundred twenty‐six calves, 0 to 114 days. Methods...
Although atrial fibrillation (AF) can be successfully treated in horses, recurrence occurs frequently. In humans, function after cardioversion predict recurrence.To examine the prognostic value of mechanical at 24 hours and other potential predictor variables for AF horses.117 horses 4 referral centers.Retrospective study. Inclusion criteria were successful cardioversion, echocardiography ≥4 months follow-up. To determine factors associated with recurrence, a multivariable survival model was...
Nonendoscopic bronchoalveolar lavage (BAL) is a practical alternative for deep nasopharyngeal swab (DNS) to sample the airways of large number calves in short period time. The extent commensal overgrowth and agreement BAL with DNS culture results preweaned are unknown.To compare bacterial between samples.A total 183 (144 bovine respiratory disease 39 healthy animals).Cross-sectional study. Deep samples were taken from each calf cultured detect Pasteurellaceae Mycoplasma bovis. Agreement...
Implementation of Third-Generation Sequencing approaches for Whole Genome (WGS) all-in-one diagnostics in human and veterinary medicine, requires the rapid accurate generation consensus genomes. Over last years, Oxford Nanopore Technologies (ONT) released various new devices (e.g. Flongle R9.4.1 flow cell) bioinformatics tools 2019-released Bonito basecaller), allowing cheap user-friendly cost-efficient introduction NGS workflows. While single read, overall accuracies, completeness genome...
Mycoplasma bovis causes many health and welfare problems in cattle. Due to the absence of clear insights regarding transmission dynamics lack a registered vaccine Europe, control an outbreak depends mainly on antimicrobial therapy. Unfortunately, susceptibility testing (AST) is usually not performed, because it time-consuming no standard protocol or clinical breakpoints are available. Fast identification genetic markers associated with acquired resistance may at least partly resolve former...
Abstract Background Respiratory infections are the main indication for antimicrobial use in calves. Optimal treatment duration currently is unknown, but shorter would likely decrease selection resistance. Hypothesis/Objectives Determine differences cure rate and healing time between animals treated with florfenicol oxytetracycline a natural outbreak of respiratory disease using reaeration observed on thoracic ultrasound examination as criterion. Animals Commercial farm housing 130, 3 to 9...
For successful development and adoption of technology on dairy farms, farmers need to be included in the innovation process. However, design agricultural technologies usually takes a top-down approach with little involvement end-users at early stages. Living Labs offer methodology that involve throughout process emphasize importance understanding users' needs. Currently, exploration farmers' needs has been limited specific types (e.g., smartphone apps) adult cattle. The aim this study was...
ABSTRACT Clostridium difficile strains were sampled periodically from 50 animals at a single veal calf farm over period of 6 months. At arrival, 10% C. positive, and the peak incidence was determined to occur age 18 days (16%). The prevalence then decreased, slaughter, could not be isolated. Six different PCR ribotypes detected, within ribotype differentiated further by pulsed-field gel electrophoresis (PFGE). diversity high up animal days, but later sampling points, 078 highly related 126...
Abstract Bovine necrohemorrhagic enteritis is a major cause of mortality in veal calves. Clostridium perfringens considered as the causative agent, but there has been controversy on toxins responsible for disease. Recently, it demonstrated that variety C . type A strains can induce lesions calf intestinal loop assay. These results put forward alpha toxin and perfringolysin potential toxins, since both are produced by all strains. The importance pathogenesis bovine not studied before....