Nnamdi Nwosu

ORCID: 0000-0003-1028-242X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Nutrition, Genetics, and Disease
  • Consumer Attitudes and Food Labeling
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Family and Patient Care in Intensive Care Units
  • Respiratory Support and Mechanisms
  • Blood Pressure and Hypertension Studies
  • Obstructive Sleep Apnea Research
  • Lung Cancer Treatments and Mutations
  • Long-Term Effects of COVID-19
  • Asthma and respiratory diseases
  • Lung Cancer Diagnosis and Treatment
  • Air Quality and Health Impacts
  • Respiratory and Cough-Related Research
  • Disaster Response and Management
  • Inhalation and Respiratory Drug Delivery
  • Global Cancer Incidence and Screening
  • Neuroscience of respiration and sleep
  • Cardiac Health and Mental Health
  • Lipoproteins and Cardiovascular Health
  • Thermal Regulation in Medicine
  • Public Health and Nutrition
  • Infection Control and Ventilation
  • Sleep and related disorders
  • HIV-related health complications and treatments
  • Smoking Behavior and Cessation

University of Nigeria Teaching Hospital
2016-2025

Enugu State University of Science and Technology
2018-2022

University of Nigeria
2016-2022

Aintree University Hospitals NHS Foundation Trust
2021

University of Liverpool
2015-2021

Manchester University NHS Foundation Trust
2018

Royal Liverpool University Hospital
2015

Air pollution is a major global public health issue causing considerable morbidity and mortality. Measuring levels of air pollutants facilitating access to the data has been identified as pathway raise awareness initiate dialogue between relevant stakeholders. Low-and middle-income countries (LMICs) urgently need simple, low-cost approaches generate such data, especially in settings with no or unreliable data. We established network easy-to-use quality sensors (PurpleAir-II-SD) monitor fine...

10.3390/atmos13101593 article EN cc-by Atmosphere 2022-09-29

Essential hypertension is the most common noncommunicable disease (NCD), affecting more than half adult population in many countries and being major NCD contributor to double burden of developing countries. We undertook a survey awareness, treatment, control primary secondary referral health care clinics Enugu, Nigeria, compared these data with those obtained local community surveys. The prevalence clinic (9.2%) was lower previously reported (42.2%), while, clinic, 70.3% patients attending...

10.1155/2016/5628453 article EN cc-by International Journal of Hypertension 2016-01-01

Asthma care imposes economic burden on affected patients. Patient costs for asthma have not been documented in Africa. We aimed to determine the out-of-pocket cost of follow-up incurred by patients Nigeria. conducted a cross-sectional study three tertiary hospitals southeastern and northwestern Poorly controlled attending visit respiratory clinic were surveyed. Sociodemographic, health-seeking behavior, data collected using structured questionnaire. Of 110 who completed study, 56 (51%)...

10.1155/2014/768378 article EN Journal of Respiratory Medicine 2014-03-31

Low-density lipoprotein cholesterol (LDLC) is a modifiable risk factor for atherosclerotic cardiovascular disease, therefore needs to be assessed and monitored. Direct homogeneous assays various formulas exist determine LDLC. We aimed compare the directly measured LDL (dLDLC) with ten estimating LDLC.This was 2-year retrospective study of fasting lipid profile results obtained from HIV-positive patients attending an outpatient clinic at University Nigeria Teaching Hospital, Enugu, Nigeria,...

10.4103/0974-2727.199632 article EN cc-by-nc-nd Journal of Laboratory Physicians 2017-02-07

Context: Spirometry with reversibility testing is the gold standard for definitive diagnosis of bronchial asthma. However, even in those established asthma test result may subsequently become negative. results also be normal during exacerbation-free intervals. Aims: This study assessed role spirometry diagnostic evaluation and determined ventilatory patterns patients presumptive using proportion who showed positive test. Patients Methods: was a retrospective carried out at teaching hospital...

10.4103/ijrc.ijrc_41_18 article EN Indian Journal of Respiratory Care 2022-12-05

Objectives: The prevalence of obstructive sleep apnea (OSA) is rising globally with its associated morbidity and mortality. Although OSA hypertension the leading cause secondary resistant hypertension, presence usually not actively sought during clinical evaluation hypertensive patients resulting in a missed opportunity to treat condition. This study assessed high risk excessive daytime sleepiness (EDS) among patients. It also pattern symptoms participants. Materials Methods: We used...

10.25259/jpats_9_2023 article EN Journal of the Pan African Thoracic Society 2023-09-30

Objectives: To validate an inductive model of the diet-genome interaction in aetiopathogenesis hypertension, derived from lifelong observation dietary determinants phenotypic expression psoriasis (cpcpsoriasis.blogspot.com), with side benefit on blood pressure and related parameters (Chijioke 2012 JHypertension 30). Methods: An open clinical trial involving withdrawal postulated egregious ingredients. Consenting study participants (SPs) mild to moderate hypertension (139mmHg < systolic BP...

10.1097/01.hjh.0000549302.85084.cd article EN Journal of Hypertension 2018-10-01

Objective: The epidemiological association between psoriasis, hypertension, diabetes and the metabolic syndrome (Mrowietz 2006 Dermatol Res 298:309; Qureshi 2009 Arch 145;379) suggests a common inflammatory aetiopathogenesis (Spah 2008 BrJDermatol 159S2:10). validate model (induced from observation of dietary effects on psoriasis with side benefit blood pressure, Chijioke 2012 J Hypertension 30esuppl1:p158) aetiopathogenic diet–genome interaction in hypertension. Design Method: An open...

10.1097/01.hjh.0000500705.74726.fe article EN Journal of Hypertension 2016-09-01

Abstract Background Acute respiratory failure, a major cause of death in COVID-19, is managed with high-flow oxygen therapy via invasive mechanical ventilation. In resource-limited settings like Nigeria, the shortage ventilators and supply makes this option challenging. Evidence-based non-invasive alternatives to ventilation such as use continuous positive airway pressure (CPAP) devices exist, but there have been concerns that may expose healthcare workers infection from aerosolized...

10.1186/s43058-021-00193-y article EN cc-by Implementation Science Communications 2021-08-26

Community-acquired pneumonia is a common condition and 6–24% of patients will fail to improve as expected. We present patient who was initially treated for community-acquired but did not make the anticipated recovery. explore potential differentials, investigation management rare we subsequently diagnosed.

10.4997/jrcpe.2018.205 article EN The Journal of the Royal College of Physicians of Edinburgh 2018-06-01

Healthcare worker's hands are route for cross-transmission of potentially harmful germs between patients in a healthcare facility. As hand washing is an established cost-effective measure infection control, hygiene knowledge and compliance with the recommended steps essential to control healthcare-associated infections (HCAI). We assessed practice among nurses at University Nigeria Teaching Hospital (UNTH), Enugu. A cross-sectional study was carried out from 14th September 24th December 2023...

10.1186/s12912-024-02519-2 article EN cc-by-nc-nd BMC Nursing 2024-12-02

Objective: Lifelong observational study of psoriasis (with eschewal suppressive drug treatments) and dietary dependence its phenotypic expression. Develop an inductive model the diet – genome interaction that engenders chronic disease. Test this by conducting open controlled trial Personalized Food Avoidance Dietary Approach to Stop Hypertension (PFADASH). Design method: textual photographic diary records (cpcpsoriasis.blogspot.com) inspired in which amphiphilic fats promote adverse gene...

10.1097/01.hjh.0000748240.54356.56 article EN Journal of Hypertension 2021-04-01

<b>Background:</b> Tobacco smoking is a leading cause of preventable morbidity and mortality globally. Health care professionals have very unique role in motivating people to quit knowledge the consequences necessary initiating cessation. <b>Objectives:</b> This study aimed assess tobacco use, its health consequence attitude regarding control among workers Enugu, Nigeria. <b>Methods:</b> was cross-sectional survey carried out adult at tertiary hospital from June August 2018. The Global Adult...

10.1183/13993003.congress-2019.pa4458 article EN 2019-09-28

<h3>Introduction and objectives</h3> FDG PET-CT scans are a valuable tool in the diagnosis staging of lung cancer, but their growing use other diseases can cause resource issues, some cases they may be ordered by non-specialists further congesting patient pathway. To study this further, we looked at referral patterns for cancer our hospital, paying particular attention to reason scan referring clinician. <h3>Methods</h3> A retrospective audit was undertaken all performed investigation...

10.1136/thoraxjnl-2015-207770.306 article EN Thorax 2015-11-12

Background: Symptoms of anxiety disorders vary widely among physically ill patients. Early detection and treatment will reduce the economic burden common medical provide empirical data for public health educators policy makers development guidelines workers care givers. Objectives: The objective present study was to determine correlates predictors symptoms based on Hospital depression scores patients attending outpatient clinic in a Tertiary hospital Enugu South East Nigeria. Methods: This...

10.4314/jcm.v23i2.3 article EN cc-by-nc-sa International Journal of Medicine and Health Development 2018-01-01

ABSTRACT Affordable novel strategies are needed to treat COVID-19 cases complicated by respiratory compromise in resource limited settings. We report a mixed-methods pre-post assessment of 1) the useability CPAP/O2 helmet non-invasive ventilation (NIV) COVID-19, at ∼ 1% cost mechanical ventilation; 2) effectiveness train-the-trainer practice facilitation intervention; and 3) whether use NIV was associated with increased infection among healthcare workers. At baseline, eight treatment centers...

10.1101/2022.08.30.22279372 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2022-09-01

<title>Abstract</title> <bold>Background</bold>Hypertension is a leading cause of non-communicable morbidity in Sub Saharan Africa. Recent studies suggest and increase the prevalence hypertension rural Africa.<bold>Methods</bold>Using a<bold/>three-phase approach, WHO STEPS-wise approach to surveillance noncommunicable diseases was used determine settlement Enugu State, Southeast Nigeria. Blood pressure measurement done according guidelines European Society...

10.21203/rs.3.rs-1921152/v1 preprint EN cc-by Research Square (Research Square) 2022-09-07

<h3>Introduction and Objective</h3> Long COVID or ongoing symptoms post-acute infection can affect up to 20% of patients.<sup>1</sup> Dyspnoea be a cardinal symptom have significant impact on patients' quality life ability function in society. NHS England devised five-point plan for long which included dedicated post assessment clinics.<sup>2</sup> We aimed review whether duration influenced the severity perceived dyspnoea (using Borg score) breathlessness MRC score). <h3>Methods</h3>...

10.1136/thorax-2021-btsabstracts.249 article EN 2021-11-01

<h3>Background</h3> A growing proportion of patients experience ongoing symptoms for more than 12 weeks following an initial COVID-19 illness. Long COVID or post-COVID syndrome is increasing burden to the NHS. NHS England has mandated setup regional long clinics manage this demand.<sup>1</sup> There very little understanding range and symptom patients. <h3>Aims</h3> We describe self-reported compare breathlessness fatigue scoring referred Cheshire Merseyside assessment hub, which serves a...

10.1136/thorax-2021-btsabstracts.248 article EN 2021-11-01
Coming Soon ...