- Biomimetic flight and propulsion mechanisms
- Micro and Nano Robotics
- Lattice Boltzmann Simulation Studies
- Immune Cell Function and Interaction
- Aeolian processes and effects
- Sports Dynamics and Biomechanics
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- Species Distribution and Climate Change
- Robotic Locomotion and Control
- Career Development and Diversity
- Genetics, Bioinformatics, and Biomedical Research
- Modular Robots and Swarm Intelligence
- Adipose Tissue and Metabolism
- Neurobiology and Insect Physiology Research
- Fluid Dynamics and Mixing
- Tree Root and Stability Studies
- Air Quality and Health Impacts
- Thermoregulation and physiological responses
- Exercise and Physiological Responses
- Energy and Environment Impacts
- Particle Dynamics in Fluid Flows
- Plant Surface Properties and Treatments
- Selenium in Biological Systems
- Nuclear Engineering Thermal-Hydraulics
University of Cincinnati
2017-2024
University of Richmond
2020-2023
North Carolina State University
2021-2022
University of North Carolina at Chapel Hill
2010-2019
Applied Physical Sciences (United States)
2019
University of North Carolina Health Care
2010
Models that are both spatially and temporally dynamic needed to forecast where when non-native pests pathogens likely spread, provide advance information for natural resource managers. The potential US range of the invasive spotted lanternfly (SLF, Lycorma delicatula) has been modeled, but until now, it could reach West Coast's multi-billion-dollar fruit industry unknown. We used process-based modeling spread SLF assuming no treatments control populations occur. found a low probability first...
The aerodynamics of flapping flight for the smallest insects such as thrips is often characterized by a 'clap and fling' wings at end upstroke beginning downstroke. These fly Reynolds numbers (Re) order 10 or less where viscous effects are significant. Although this wing motion known to augment lift generated during flight, drag required fling apart scale an magnitude larger than corresponding force acting on single wing. As opposing forces normal each nearly cancel fling, these large do not...
The smallest flying insects commonly possess wings with long bristles. Little quantitative information is available on the morphology of these bristles, and their functional importance remains a mystery. In this study, we (1) collected morphological data bristles 23 species Mymaridae by analyzing high-resolution photographs (2) used immersed boundary method to determine via numerical simulation whether bristled reduced force required fling apart while still maintaining lift. effects Reynolds...
Enhancing antiviral host defense responses through nutritional supplementation would be an attractive strategy in the fight against influenza. Using inoculation with live attenuated influenza virus (LAIV) as infection model, we have recently shown that ingestion of sulforaphane-containing broccoli sprout homogenates (BSH) reduces markers viral load nose. To investigate systemic effects short-term BSH context LAIV-inoculation, examined peripheral blood immune cell populations non-smoking...
Background Smokers have increased susceptibility and altered innate host defense responses to influenza virus infection. Broccoli sprouts are a source of the Nrf2 activating agentsulforaphane, short term ingestion broccoli sprout homogenates (BSH) has been shown reduce nasal inflammatory oxidant pollutants. Objectives Assess effects BSH on cytokines, replication, Nrf2-dependent enzyme expression in smokers nonsmokers. Methods We conducted randomized, double-blind, placebo-controlled trial...
Flexible plants, fungi and sessile animals reconfigure in wind water to reduce the drag acting upon them. In strong winds flood waters, for example, leaves roll up into cone shapes that compared with rigid objects of similar surface area. Less understood is how a leaf attached flexible stalk will stably an unsteady flow. Previous mathematical physical models have only considered case sheet tether steady this paper, dynamics flow around wild ginger Hexastylis arifolia violet Viola...
In contrast to larger species, little is known about the flight of smallest flying insects, such as thrips and fairyflies. These tiny animals range from 300 1000 microns in length fly at Reynolds numbers ranging 4 60. Previous work with numerical physical models have shown that aerodynamics these diminutive insects significantly different animals, but most studies relied on two-dimensional approximations. There can, however, be significant differences between two- three-dimensional flows,...
We propose a reciprocal, self-propelled model swimmer at intermediate Reynolds numbers ($Re$). Our consists of two unequal spheres that oscillate in antiphase generating nonlinear steady streaming (SS) flows. show computationally the SS flows enable to propel itself, and also switch direction as $Re$ increases. quantify transition swimming by collapsing our data on critical directions corresponds reversal Based findings, we can be an important physical mechanism for motility $Re$.
Ecological forecasts will be best suited to inform intervention strategies if they are accessible a diversity of decision-makers. Researchers developing intuitive forecasting interfaces guide stakeholders through the development and visualization results. Yet, few studies date have evaluated how user interface design facilitates coordinated, cross-boundary management required for controlling biological invasions. We used participatory approach develop complementary tangible online...
Objective: Lineage tracing studies have shown that advanced atherosclerosis causes vascular smooth muscle cells (VSMCs) to become macrophage-like (MLCs), which increases inflammation. We investigated whether the RNA binding protein human antigen R (HuR) and inflammatory receptor protease activated 2 (PAR2) accelerate VSMC-MLC in a mouse model of atherosclerosis. Methods Results: Downregulation VSMC migration cytokine release Par2 -/- mice reduces atherosclerotic lesion area compared...
In the early 2000s, our primarily undergraduate, white institution (PUI/PWI), began recruiting and enrolling higher numbers of students color first-generation college students. However, like many peer institutions, established pedagogies mindsets did not provide these an educational experience to enable them persist thrive in STEM. Realizing need systematically address lack inclusivity science majors, 2012 faculty from multiple disciplines developed Science, Math, Research Training (SMART)...
Carbon nanodots (CDs) have drawn significant attention for their potential uses in diagnostic and therapeutic applications due to small size, tissue biocompatibility, stable photoluminescence, modifiable surface groups. However, the effect of cargo molecules on CD photoluminescence ability interact with tissues are not fully understood. Our previous work has shown that CDs produced from acidic oxidation carbon nanopowder can bind mineralized bone high affinity specificity a zebrafish animal...
Abstract Regulating BCR-mediated adaptive immune responses and subsequent immunoglobulin (Ig) secretion is critical for normal function. Defective regulation could lead to chronic inflammation, autoimmunity, or cancer. Several regulatory mechanisms control the threshold B cell activation Ig secretion. One mechanism negatively regulates BCR through coligation of FcγRIIb recruitment SHIP. It was thought that FcγRIIB primary by which humoral were terminated. However, mice deficient in do not...