A5001480287- Parkinson's Disease Mechanisms and Treatments
- Image Processing and 3D Reconstruction
- CRISPR and Genetic Engineering
- Autophagy in Disease and Therapy
- Monoclonal and Polyclonal Antibodies Research
- Chemokine receptors and signaling
- Receptor Mechanisms and Signaling
Vrije Universiteit Amsterdam
2025
National Hospital for Neurology and Neurosurgery
2020-2022
University College London
2020-2022
Abstract Parkinson’s disease is a common incurable neurodegenerative disease. The identification of genetic variants via genome-wide association studies has considerably advanced our understanding the risk. Understanding functional significance risk loci now critical step towards translating these advances into an enhanced biological Impaired mitophagy key causative pathway in familial disease, but its relevance to idiopathic unclear. We used screening assay evaluate genes identified through...
CXCR4 is an important therapeutic target for hematopoietic stem cell mobilization, which enhances the success of autologous transplantation treating blood cancers such as lymphomas and myeloma. As has been shown to be involved in various inflammatory diseases, cancer progression, entry by human immunodeficiency virus, understanding molecular mechanism inhibitors potential implications a wide area diseases. Here, we present exploratory study involves pharmacological characterization TG-0054...
ABSTRACT Parkinson’s disease (PD) is a common incurable neurodegenerative disease. The identification of genetic variants via genome-wide association studies (GWAS) has considerably advanced our understanding the PD risk. Understanding functional significance risk loci now critical step towards translating these advances into an enhanced biological Impaired mitophagy key causative pathway in familial PD, but its relevance to idiopathic unclear. We used screening assay evaluate genes...