The use of physical exercise and computer-based stimulation programs is considered to be a promising method for rehabilitation cognitive dysfunction after stroke. article presents the results complex strategy in 58-year old patient with an acute ischemic stroke hemiparesis moderate dysfunction. optimized approach consisted cyclic mechanotherapy combined training performed by himself including tablet PC technology. Changes motor were assessed quantitative scales functioning neuropsychologic...

Background: Pituitary adenoma is not as infrequent thought previously. The prevalence of macroadenomas in general population up to 0.16–0.2%. Magnetic resonance imaging (MRI) a method choice diagnosis pituitary adenomas. Until now, specifics adenomas with various hormonal activities have been discussed. Aim: To analyze comparatively the size, volumes and growth direction activities. Materials methods: We analyzed MRI images 305 patients hypophyseal more than 10 mm diameter, among them...

At present, there is no "golden standard" of diagnosis inflammatory bowel disease. Each and every individual case requires a thorough analysis clinical symptoms in their association with endoscopic, histological, radiological laboratory data. This review paper analyzes both conventional novel methods investigations. Some them have changed significance from the to rare limited application promising, then frequent currently sporadic use small enema. Traditional ileocolonoscopy maintains its...

The primary appendiceal cancer is one of the rarest malignancies. Its counts for 0.5% all colon and does not exceed few bips in surgically removed appendices. disease have specific signs. It can imitate acute appendicitis, its complications, or a uterine appendages. commonly diagnosed during pathomorphological investigation after surgery. A clinical case 58-yearold female patient with tumor appendix presented paper. Initially was thought to be an appendicular infiltrate. During patient's...

According to foreign data somatotropinoma volume reduction was noted more than at a half of the patients receiving somatostatin analogs within 12 months as first line acromegaly treatment, however there is no about tumor-supp ressive effect Octreotid-depot. We assessed during Octreotid-depot treatment in with an active acromegaly, and also tried indentify possible predictors tumor somastatin treatment. Open prospective study include 18 (16 women, 2 men, age from 22 till 76 years old); after...

To study the diagnosis and treatment of non-alcoholic Wernicke-Korsakoff syndrome (WKS).Eight patients (5 men 3 women), mean age 38,9±1,4 years, with WKS developed due to acute gastrointestinal tract (GIT) disease (3 patients), exacerbation chronic GIT malabsorption (2 patients) after surgery on upper were included in study.The manifested consciousness disturbance, symptoms ataxia, eye movement disorders bulbar that 24-48 h. Treatment resistant tonic-clonic seizures 1 patient. MRI revealed...

To study the prevalence, clinical features and treatment of diabetic asymmetric proximal neuropathy (DAPN).Four hundred forty-five patients with diabetes mellitus (DM), 257 women 188 men, mean age 47.6±0.5 years, including 163 DM type I 282 II, were examined.Distal symmetric sensory motor polyneuropathy was found in 62% patients, autonomic 25.6%, somatic mononeuropathy 28.5%, DAPN 7.9%. more frequent II (9.6), poor control glycemia duration than 5 years. Pain paresthesia a zone innervation...

Objective: to determine whether liver computed tomography (CT) perfusion imaging can assess hemodynamics in patients with fibrosis and cirrhosis as a result of chronic viral hepatitis C (CVHC). Subjects methods. The prospective study conducted at the Department Radiation Diagnosis, M.F. Vladimirsky Moscow Regional Research Clinical Institute, enrolled 61 CVHC, whom 26 had received antiviral therapy (AVT) achieved sustained virological response (SVR) 24 weeks after end treatment. All...

Benign pituitary tumors are the most common sellar neoplasms. Lesions larger than 39 mm in maximum dimension called giant. They rare, and, therefore, there few data on clinical and morphological features of giant with different hormonal activity.The aim this study was to identify functional activity.We analyzed clinical, laboratory, instrumental examinations 351 patients diagnosed macroadenomas at Moscow Regional Research Clinical Institute period between 2008 2017: were 144 hormonally...

The two-year study of the efficacy Ifnb-1B (infibeta) in patients with relapsing-remitting (RRS) and secondary progressive multiple sclerosis (SPMS) Moscow region criteria NEDA-3.Three hundred patients, 81 men 219 women, aged from 18 to 67 years, including 227 RRS 73 SPMS, were studied. duration disease was 0.5 39 level neurological deficit on EDSS scale 1 6.5 points. All received infibeta.During treatment infibeta, chance exacerbation decreased by an average 39.4 times (OR 95% CI;...

Rectal cancer occupies one of the leading places in structure mortality both sexes, with only radical method treatment is surgery. For planning surgical treatment, it important to assess metastatic lesion locoregional lymph nodes, presence extramural lymphovascular invasion, which an predictor recurrence disease, as well indicator early appearance distant metastases. The effectiveness and reliability preoperative staging low rectal has increased significantly after introduction into clinical...

Плевропульмональная бластома – редкая первичная злокачественная опухоль, исходящая из легких и/или плевры. Чаще встречается у детей младшего возраста. Отличается от других опухолей легкого гистопатологическими особенностями. Представлен клинический случай опухоли ребенка 3 лет. Первично патология была расценена как плевропневмония, а после выполнения компьютерной томографии средостения. Современные данные свидетельствуют о трудностях диагностики плевропульмональной бластомы даже при...

Представлен случай кистозно-аденоматоидной мальформации легкого у новорожденного. Описаны методы лучевой диагностики и оперативного лечения этой врожденной аномалии развития легких: ультразвуковое исследование плода в пренатальном периоде, рентгенография компьютерная томография – антенатальном.

Предиктором уменьшения объема соматотропиномы обычно является нормализация уровней соматотропного гормона (СТГ) и инсулиноподобного ростового фактора 1-го типа (ИРФ-1) на фоне медикаментозного лечения. Однако отмечаются случаи диссоциации биохимического туморсупрессивного эффектов. Представляем пациентку, у которой лечения максимальными дозами аналогов соматостатина (октреотид ЛАР 40 мг) в течение 36 месяцев отмечалось уменьшение СТГ с 34,3 до 3,1 нг/мл снижение ИРФ-1 796 415 (верхняя...

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

The neurotoxicity of general anesthetic drugs still appears as a relevant interdisciplinary problem. All anesthetics that are currently in use exhibit neurotoxic effect on the brain at all stages its development. It is impossible to evaluate negative impact without considering surgical injury, intraoperative complications, pain syndrome, main and concomitant diseases. We report case hypoxic injury early postoperative period child with severe comorbidities perinatal complications anamnesis.

Inflammatory bowel diseases (IBD) are commonly associated with extraintestinal manifestations, hematological disorders being the most special among them. In some cases, they dominate clinical picture masking intestinal manifestations of underlying disease. Aplastic anemia is an extremely rare IBD manifestation. There only two cases aplastic ulcerative colitis and non Crohn's disease reported in literature. Combination В₁₂-deficient more prevalent, but seen usually after than 20 cm ileus has...

The article describes the experience in effective use of second-generation EGFR II blocker palliative target therapy EGFRnegative lung adenocarcinoma. afatinib fifth-line EGFR-negative adenocarcinoma allowed us to achieve a significant positive response lungs and improve patient’s quality life.

Balo's concentric sclerosis (BCS) is a rare demyelinating disease, first described by Hungarian neurologist Josef Balo in 1928. BCS occurs predominantly young adults, the average age of onset disease - 34 years (range from 3 to 62 years). Our case report describes 27-year woman with acute progressive right-side pyramidal weakness, MRI results showed variant demyelination as sclerosis.Концентрический склероз Бало представляет собой редкое демиелинизирующее заболевание, которое впервые было...

Аномалии ротации и фиксации кишечника являются одним из врожденных дефектов положения в брюшной полости вследствие не-полного или неправильного его поворота, относятся к группе нарушений развития кишки, которые могут произойти на любом этапе формирования кишечной трубки. толстой кишки часто сопровождаются функциональными расстройствами, развитием осложнений воз-никновением воспалительных заболеваний опухолевых процессов. Неспецифичность отсутствие симптомов значительно затрудняет...

Relevance : Most diffuse liver diseases lead to fibrosis over time with the risk of cirrhosis. With progressive and cirrhosis both physical properties hepatic parenchyma its hemodynamics change. The only reliable method for determining stage disease is puncture biopsy subsequent histological examination, but this invasive associated complications. Currently, determination severity based on clinical data (the Child-Pugh scale) elastography considered be main non-invasive instrumental method....