Propofol (2,6-diisopropylphenol) is a hypnotic intravenous agent with in vivo antioxidant properties. This study was undertaken to examine the vitro activity of propofol using different tests including by 1,1-diphenyl-2-picryl-hydrazil (DPPH.) radical scavenging, metal chelating, hydrogen peroxide superoxide anion reducing power and total activities. At concentrations 25, 50, 75 microg/ml, exhibited 97.7, 98.6 100% inhibition on peroxidation linoleic acid emulsion, respectively. On other...

Summary Background: Postoperative vomiting (POV) is a common complication after tonsillectomy. Dexamethasone known to decrease postsurgical vomiting. In this study, we compared the effects of dexamethasone alone plus propofol on postoperative in children undergoing Methods: randomized double‐blinded evaluated 80 healthy children, aged 4–12 years, who underwent tonsillectomy with or without adenoidectomy. After anesthesia was induced by inhalation sevoflurane, 0.15 mg·kg −1 and 2 μg·kg...

We aimed to determine the effect of ondansetron and dexamethasone on preventing post-operative nausea vomiting (PONV). Sixty women undergoing laparoscopic gynaecological surgery were randomized receive 4 mg, 8 mg or saline. Drugs administered 2 min before induction anaesthesia, anaesthesia analgesic regimens standardized. The incidence PONV in first 24 h after operation was 35% group, 55% group 85% control group. A significant difference between groups only seen 3 post-operatively. In this...

Spontaneous esophageal perforation is an uncommon finding requiring prompt diagnosis and immediate surgery because of its high mortality rate. Esophageal rupture secondary to severe vomiting in pregnancy extremely rare only four cases have been published the literature. We report case a 20-year-old female whom early resulted with subcutaneous emphysema. The was made 48 h later. patient had undergone surgical treatment postoperative period uneventful. unusual cause interesting clinical course...

Epidural catheter placement offers flexibility in block management. However, during epidural insertion, complications such as paresthesia and venous subarachnoid cannulation may occur, suboptimal can affect the quality of anesthesia. We performed this prospective, randomized, double-blind study to assess effect a single-injection dose local anesthetic (20 mL 2% lidocaine) through needle priming solution into space before insertion. randomized 240 patients 2 equal groups measured anesthesia...

Tramadol is an important spinal drug which produces analgesia following intrathecal injection. It well known that fatty acids (FAs) play role in membrane fluidity of the blood-brain barrier (BBB) tissue, blocks and/or controls transportation toxic substances into brain. The aim this study was to investigate effect a (tramadol) on concentrations and compositions acid BBB tissues New Zealand male rabbits. total cellular profiles three cord sections (cervical, thoracal lumbar) brain rabbits...

This study evaluated the efficacy of tropisetron compared with and a subhypnotic propofol infusion in preventing postoperative vomiting following tonsillectomy. One hundred forty healthy children, aged four to 12 years, undergoing tonsillectomy were recruited randomised, double-blind study. After induction sevoflurane, anaesthesia was maintained sevoflurane nitrous oxide. All patients received (0.2 mg/kg up 5 mg; intravenously) fentanyl (2 μg/kg; intubated after atracurium which reversed...

Although various local anesthesia techniques have been suggested to decrease pain and discomfort during a transrectal ultrasound (TRUS)-guided prostate biopsy, the best method has not yet defined. The present prospective, double-blind, randomized study aims investigate clinical efficacy of 'walking' caudal block compared with an intrarectal lidocaine gel for this procedure.One hundred patients were randomly assigned two groups. In group, 10 ml containing 2% was given intrarectally. 20 0.1%...

To investigate whether a 2% lidocaine addition to 0.5% bupivacaine that is used in lateral sagittal infraclavicular block, when administered an upper extremity surgery, decreases the block onset time, drug effect and activity compared with alone. Materials methods: This study was performed on 120 American Society of Anesthesiology classification I-II patients who were 18–65 years old scheduled undergo surgery. The group testing as follows: 20 mL (5 mg/mL) bupivacaine, 10 + (20 lidocaine,...

In Brief We describe a 65-yr-old woman, whose right lower limb had been amputated at the mid-femoral level because of complicated femur fracture sustained age 5 yr. After amputation, she experienced phantom pain (PLP), which gradually decreased in intensity but persisted for 60 At this point diminished progressively, parallel with evolution cauda equina compression caused by an intraspinal tumor. The PLP reappeared over 3 mo after surgical removal IMPLICATIONS: present case (PLP) leg...

This report describes a case in which large anterior osteophyte on the C2 and C3 vertebrae, due to ankylosing spondylitis, resulted distortion of anatomy upper airway difficult intubation. Ankylosing spondylitis (AS) is progressive inflammatory disease, characterized by stiffening joints ligaments. Stiffness cervical spine, atlanto‐occipital, temporomandibular cricoarytenoid may cause intubation ( 1 ). associated with AS,

Objectives: Preemptive analgesia is an important factor in controlling the postoperative pain and avoiding stress response caused by surgery.We aim to compare impact of gabapentin nimesulide on analgesic consumption visual analog scale (VAS) as well any potential side effects, those placebo group.Methods: Ninety patients aged 18-70 under ASA I-II risk, who were undergo Functional Endoscopic Sinus Surgery (FESS), included study.Patients randomized into three groups.One hour before surgery,...

Cardiopulmonary bypass (CPB) is associated with the release of S100β and neuron-specific enolase (NSE) indicating cerebral cell injury. The purpose present study was to evaluate effect propofol sevoflurane on NSE levels in patients undergoing coronary artery grafting (CABG).Twenty male CABG were randomly allocated into two groups. One group received (GS) other (GP). Arterial blood samples for analysis taken preoperatively (T1), 30 min after initiation CPB (T2), at end (T3), 1 (T4), 6 (T5) 24...

This study compared the efficacy and adverse effects of three low doses morphine (10, 15 30 μg.kg 1 ) for caudal epidural analgesia in children undergoing circumcision. A total 135 boys outpatient circumcision were randomly assigned to receive 10, or morphine. Anaesthesia was induced maintained with propofol. After induction, added 0.5 ml.kg 1% lignocaine solution adrenaline 5μg.ml injected caudally. quality, postoperative pain events a 24-hour period evaluated. Paracetamol (20 mg. kg’...

To evaluate the potential advantages of combined general and epidural anesthesia for major gynecological oncological surgeries.