Smart hydrogels, or stimuli-responsive are three-dimensional networks composed of crosslinked hydrophilic polymer chains that able to dramatically change their volume and other properties in response environmental stimuli such as temperature, pH certain chemicals. Rapid significant high elasticity critical for the versatility smart hydrogels. Here we report synthesis hydrogels which rapidly responsive, highly swellable stretchable, by constructing a nano-structured architecture with...

Novel poly( N ‐isopropylacrylamide)‐clay (PNIPAM‐clay) nanocomposite (NC) hydrogels with both excellent responsive bending and elastic properties are developed as temperature‐controlled manipulators. The PNIPAM‐clay NC structure provides the hydrogel mechanical property, thermoresponsive property of is achieved by designing an asymmetrical distribution nanoclays across thickness. simply fabricated a two‐step photo polymerization. resulted from unequal forces generated thermoinduced...

A novel reduced graphene oxide/poly(2-acrylamido-2-methylpropanesulfonic acid-co-acrylamide) (rGO/poly(AMPS-co-AAm)) nanocomposite hydrogel that possesses excellent electro-response and mechanical properties has been successfully developed. The rGO nanosheets homogeneously dispersed in the hydrogels could provide prominent conductive platforms for promoting ion transport inside to generate significant osmotic pressure between outside of such hydrogels. Thus, electro-responsive rate degree...

Novel near-infrared (NIR) light-responsive poly(N-isopropylacrylamide)/graphene oxide (PNIPAM-GO) nanocomposite hydrogels with ultrahigh tensibility are prepared by incorporating sparse chemical cross-linking of small molecules physical graphene (GO) nanosheets. Combination the GO nanosheets and thermoresponsive poly(N-isopropylacrylamide) (PNIPAM) polymeric networks provides an excellent NIR property. The PNIPAM-GO is achieved simply using a very low concentration...

A hierarchical and scalable microfluidic device constructed from a combination of three building blocks enables highly controlled generation multicomponent multiple emulsions. The number, ratio size droplets, each with distinct contents being independently co-encapsulated in the same level, can be precisely controlled. are drop maker, connector liquid extractor; combinations these enable scale-up to create higher-order emulsions exceptionally diverse structures. These offer versatile...

Novel multi‐stimuli‐responsive microcapsules with adjustable controlled‐release characteristics are prepared by a microfluidic technique. The proposed composed of crosslinked chitosan acting as pH‐responsive capsule membrane, embedded magnetic nanoparticles to realize “site‐specific targeting”, and temperature‐responsive sub‐microspheres serving “micro‐valves”. By applying an external field, the smart can achieve targeting aggregation at specific sites. Due acid‐induced swelling membranes,...

Monodisperse core-shell microcapsules based on crosslinked chitosan membrane with acid-triggered burst release properties are successfully developed. The fabricated from double emulsion precursors that prepared a microfluidic approach. In neutral medium (pH 7.1), the maintain good spherical shape and structural integrity; while, in acidic 1.5 ∼ 4.7), decompose rapidly encapsulated contents completely short periods varying 39 s to 22 min. pattern proposed may make them capable for...

Graphene oxide (GO) membranes become emerging efficient filters for molecular or ionic separation due to their well-defined two-dimensional nanochannels formed by closely spaced GO sheets and tunable physicochemical properties. The stability of in aqueous solutions is a prerequisite applications. Here we show novel easy strategy fabricating with strong controllable lamellar spacing simply doping partially reduced graphene (prGO) sheets. With our prGO-doping strategy, the interlayer...

A novel type of core–shell chitosan microcapsule with programmed sequential drug release is developed by the microfluidic technique for acute gastrosis therapy. The composed a cross-linked hydrogel shell and an oily core containing both free molecules drug-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles. Before exposure to acid stimulus, resultant microcapsules can keep their structural integrity without leakage encapsulated substances. Upon acid-triggering, first achieve burst due...

Hole in one! Hole–shell microparticles (blue, see picture) with controllable structures and flexible internal surfaces have been fabricated from W/O/W emulsions. These could be used as microcontainers for the controlled capture/release of molecules, microsphere classification/separation, confined cell culture, or microreactors catalysis. Polymeric core–shell hollow interiors great potential use microencapsulation systems load/release,1–3 active protection,4 microreaction.5 Core–shell solid...

Abstract In this study, soft hydrogel walkers with electro-driven motility for cargo transport have been developed via a facile mould-assisted strategy. The consisting of polyanionic poly(2-acrylamido-2-methylpropanesulfonic acid- co -acrylamide) exhibit an arc looper-like shape two “legs” walking. can reversibly bend and stretch repeated “on/off” electro-triggers in electrolyte solution. Based on such bending/stretching behaviors, the move their to achieve one-directional walking motion...

A novel and facile assembly strategy has been successfully developed to construct smart nanocomposite (NC) hydrogels with inhomogeneous structures using nanoclay-cross-linked stimuli-responsive hydrogel subunits as building blocks via rearranged hydrogen bonding between polymers clay nanosheets. The assembled thermoresponsive poly(N-isopropylacrylamide-co-acrylamide) (poly(NIPAM-co-AM)) various exhibit excellent mechanical properties due plenty of new interactions created at the interface...

A simple and flexible approach is developed for controllable fabrication of spider-silk-like microfibers with tunable magnetic spindle-knots from biocompatible calcium alginate controlled 3D assembly water collection. Liquid jet templates volatile oil drops containing Fe3O4 nanoparticles are generated microfluidics fabricating microfibers. The structure can be precisely adjusted by simply changing the flow rates to tailor structures resultant well manipulated external fields controllably...

A novel intestinal-targeted carrier for pH-responsive protection of lactic acid bacteria in stomach and rapid release small intestine is successfully developed. The proposed composed a Ca-alginate/protamine (CAP) composite shell Lactobacillus-casei-encapsulated Ca-alginate (CA) core. carriers are prepared simply by coextrusion minifluidic subsequent adsorption method. CAP offers not only improved Lactobacillus casei to guarantee the endurance survival but also satisfactory characteristics...

Abstract Multicompartment microcapsules, with each compartment protected by a distinct stimuli‐responsive shell for versatile controlled release, are highly desired developing new‐generation microcarriers. Although many multicompartmental microcapsules have been created, most cannot combine different release styles to achieve flexible programmed sequential release. Here, one‐step template synthesis of controllable Trojan‐horse‐like is reported capsule‐in‐capsule structures from microfluidic...

Abstract Drug delivery systems that can control drug release profile to ensure a high therapeutic efficacy and reduced side effects are highly desired in pharmaceutical biomedical fields. Microparticles the most commonly used systems, because they be easily administrated patients, engineered with different structures functions for keeping stability, delivering drugs location, releasing predetermined rate well‐controlled manner. Microfluidic techniques show great power controllable generation...

This work reports on a simple and general strategy for continuous fabrication of self-propelled micromotors with photocatalytic metal-organic frameworks (MOFs) enhanced synergistic degradation organic contaminants. With emulsion microdroplets from microfluidics as templates, uniform porous decorated Fe3O4@Ag nanoparticles (Fe3O4@AgNPs) at the bottom zeolitic imidazolate framework-8@ZnO (ZIF-8@ZnONPs) surface can be synthesized. The spatial location ZIF-8@ZnONPs Fe3O4@AgNPs in is accurately...