A5003484293- Asymmetric Hydrogenation and Catalysis
- Organometallic Complex Synthesis and Catalysis
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Synthetic Organic Chemistry Methods
- Catalytic Cross-Coupling Reactions
- Catalytic Alkyne Reactions
- Asymmetric Synthesis and Catalysis
- Carbon dioxide utilization in catalysis
- Organoboron and organosilicon chemistry
- Catalytic C–H Functionalization Methods
- Synthesis and characterization of novel inorganic/organometallic compounds
- Metal complexes synthesis and properties
- Nanomaterials for catalytic reactions
- Coordination Chemistry and Organometallics
- Ammonia Synthesis and Nitrogen Reduction
- Ionic liquids properties and applications
- Organophosphorus compounds synthesis
- Crystallography and molecular interactions
- Inorganic Chemistry and Materials
- Axial and Atropisomeric Chirality Synthesis
- Hydrogen Storage and Materials
- Distributed systems and fault tolerance
- Ferrocene Chemistry and Applications
- Sulfur-Based Synthesis Techniques
Newcastle University
2016-2025
Newcastle upon Tyne Hospital
2014-2018
Mount Allison University
2014
Heidelberg University
2009-2011
Victoria University of Wellington
2010
New York University
2007
Queen's University Belfast
2001-2006
University of Newcastle Australia
2001
University College London
1991-2000
University of Waterloo
1991-1998
Gold nanoparticles stabilized by phosphine-decorated polymer immobilized ionic liquids (AuNP@PPh2-PIILP) is an extremely efficient multiproduct selective catalyst for the sodium borohydride-mediated reduction of nitrobenzene giving N-phenylhydroxylamine, azoxybenzene, or aniline as sole product under mild conditions and a very low loading. The use single nanoparticle-based partial complete nitroarenes to afford three different products with exceptionally high selectivities unprecedented....
Abstract The synthesis of phosphinoboronate esters containing a single PB bond is reported, together with preliminary reactivity studies towards range organic substrates. These compounds add readily to aldehydes, ketones, aldimines, and α,β‐unsaturated enones give primarily the corresponding 1,2‐addition products new PC bond. first examples transition‐metal‐catalyzed phosphinoborations C‐C multiple bonds in which BC are formed step also disclosed; allenes react by highly regioselective...
Highly efficient sulfide oxidation has been achieved under segmented and continuous flow using a peroxometalate-based polymer immobilised ionic liquid phase catalyst.
Phosphino-decorated polymer immobilised ionic liquid-stabilised PdNPs are highly efficient catalysts for the aqueous phase hydrogenation and transfer of aromatic nitro compounds in batch continuous flow.
Abstract magnified image Gold(I)‐triflimide (AuNTf 2 )complexes of H‐KITPHOS and o ‐MeO‐KITPHOS have been prepared shown to be efficient catalysts for a range intramolecular cyclisations afford phenols, acylindenes, alkylidene oxazoles, tetrahydropyrans lactones, in the majority cases these are superior those previously reported.
Abstract Lewis acid complexes based on copper(II) and an imidazolium‐tagged bis(oxazoline) have been used to catalyse the asymmetric Mukaiyama aldol reaction between methyl pyruvate 1‐methoxy‐1‐trimethylsilyloxypropene under homogeneous heterogeneous conditions. Although ee s obtained in ionic liquid were similar those found dichloromethane, there was a significant rate enhancement with reactions typically reaching completion within 2 min compared only 55 % conversion after 60...
Electrophilic gold(I) complexes of diphenyl- and dicyclohexylphosphino-based KITPHOS monophosphines catalyze the 5-exo-dig cycloisomerization a range propargyl amides to afford corresponding alkylidene oxazolines; in all cases catalysts formed from diphenylphosphino-substituted outperformed their dicyclohexylphosphino counterparts as well that based on triphenylphosphine, an indication biaryl/biaryl-like framework may be responsible for imparting high catalyst efficiency.
Abstract Electrophilic gold(I) triflimide (trifluoromethanesulfonimide) complexes of electron‐rich ortho,ortho′ ‐disubstituted KITPHOS (11‐dicyclohexylphosphino‐12‐phenyl‐9,10‐ethenoanthracene) monophosphines are efficient catalysts for intramolecular cycloisomerizations that afford phenols, 3‐acylindenes and methylene‐oxazolines; comparative catalyst testing showed these either competed with or outperformed based on SPHOS [2‐(2′,6′‐dimethoxybiphenyl)dicyclohexylphosphine]. An...
A linear cation-decorated polymeric support with tuneable surface properties and microstructure has been prepared by ring-opening metathesis polymerisation (ROMP) of a pyrrolidinium-functionalised norbornene-based monomer cyclooctene. The derived peroxophosphotungstate-based polymer-immobilised ionic liquid phase (PIILP) catalyst is an efficient recyclable system for the epoxidation allylic alcohols alkenes, only minor reduction in performance on successive cycles.
An aqueous phase hydrogenation of α,β-unsaturated aldehydes with remarkable selectivity for the CC double bond under mild conditions.
Abstract Palladium nanoparticles stabilized by heteroatom donor‐modified polystyrene‐based polymer immobilized ionic liquids (PdNP@HAD‐PIILP; HAD‐PPh 2 , OMe, NH CN, pyrrolidone) are highly efficient catalysts for the Suzuki‐Miyaura cross‐coupling in aqueous media under mild conditions. Catalyst modified with phosphine was consistently most as it gave high yields across a range of substrates conditions at low catalyst loadings. Incorporation polyethylene glycol into immobilised liquid...
Palladium nanoparticles stabilised by confinement in crosslinked amine-decorated, polymer immobilised ionic liquids catalyse the hydrolytic evolution of hydrogen from NaBH4 under mild conditions. A series three PIIL supports NH2-ImxPIIL (x = 1, (2a); x 2, (2b), 3, (2c); where corresponds to number imidazolium cations repeat unit) were prepared with an increasing such that bis(styryl)-based crosslinkers 1a and 1b contain one two cations, respectively, while 1c is a more extensive...
The group 4 mixed-ligand compounds [CpM{NC5H4(CR2O)-2}Cl2] (M = Ti; R Pri (1a), Ph (1b); M Zr, (2a), (2b)) have been prepared and characterized. Single-crystal X-ray analyses reveal that 1a 2b adopt four-legged piano-stool structures in which the cyclopentadienyl ligand is asymmetrically bonded pyridylalkoxide bidentate. Toluene solutions of methylaluminoxane catalyze polymerization ethylene, generating high molecular weight polymers with narrow distributions. activity titanium-...
The ter- and tetradentate N-alkoxyalkyl-β-ketoimines CH3C(O)CH2C(NCH2CHROH)CH3 {L1-3} react with diethylaluminum chloride to afford the dimeric bridged complexes [{L1-3}AlCl]2 (1a−c), which are activated by addition of propylene oxide or cyclohexene efficient initiators for ring-opening polymerization (d,l)-lactide. active species is believed be a chloroalkoxide formed nucleophilic ring opening coordinated PO migration adjacent aluminum center. resulting polymers have high molecular weight,...
Asymmetric Diels–Alder reactions using platinum complexes of BINAP, or conformationally flexible NUPHOS-type diphosphines, have been compared in dichloromethane and selected ionic liquids. Significant enhancements the enantioselectivity (Δee ≈ 20%), as well reaction rate, were achieved liquids with organic media.
Rhodium-catalyzed double [2 + 2 2] cycloaddition of 1,4-bis(diphenylphosphinoyl)buta-1,3-diyne with tethered diynes provides a straightforward, single-pot procedure for the synthesis new class tropos biaryl diphosphine, NU-BIPHEP. This methodology represents significant improvement on existing multistep procedures. Enantiopure Lewis acid platinum complexes these diphosphines are highly efficient catalysts carbonyl-ene and Diels-Alder reactions, ruthenium diphosphine-diamine catalyze...
Abstract ortho,ortho′‐ Substitution of the phosphinoalkyne‐derived aryl ring in KITPHOS (11‐dicyclohexylphosphino‐12‐phenyl‐9,10‐ethenoanthracene) monophosphines enhances performance this class ligand palladium‐catalyzed Suzuki–Miyaura cross‐couplings and Buchwald–Hartwig aminations, compared with their unsubstituted mono‐substituted counterparts. An alternative complementary synthesis has been developed two new members family, 2,6‐Me 2 ‐KITPHOS...
Abstract Imidazolium‐tagged bis(oxazolines) have been prepared and used as chiral ligands in the copper( II )‐catalysed Diels–Alder reaction of N ‐acryloyl‐ ‐crotonoyloxazolidinones with cyclopentadiene 1,3‐cyclohexadiene ionic liquid 1‐ethyl‐3‐methylimidazolium bis[(trifluoromethyl)sulfonyl]imide, [emim][NTf 2 ]. A significant substantial enhancement rate enantioselectivity was achieved ] compared dichloromethane. For example, complete conversion enantioselectivities up to 95 % were...
Thermolysis of the P-coordinated KITPHOS monophosphine complex [(p-cymene)RuCl2(KITPHOS)] in chlorobenzene at 120 °C resulted displacement p-cymene to afford [{κ(P)-η6-KITPHOS}RuCl2], first example a constrained-geometry which κ(P)-bonded diphenylphosphino group and η6-coordinated proximal phenyl ring are connected by an unsaturated two-carbon tether; both complexes form efficient catalysts for direct ortho arylation 2-phenylpyridine N-phenylpyrazole with range aryl chlorides.
The addition of phosphinoboronate ester Ph2 PBpin (pin=1,2-O2 C2 Me4 ) (1) to a number different N-heterocycles has been investigated. Reaction 1 with pyridine resulted in highly selective formation the corresponding 1,4-addition product, electron-deficient Bpin group nitrogen atom and phosphido para carbon atom. Conversely, reactions para-substituted derivatives occurred predominately afford 1,2-addition products while quinoline reacted 1,2-adduct which ultimately isomerized product....
Phosphine oxide-decorated polymer immobilized ionic liquid stabilized RuNPs catalyse the hydrogenation of aryl ketones with remarkable selectivity for CO bond, complete to cyclohexylalcohol and levulinic acid γ-valerolactone.