A5038770484- Infant Nutrition and Health
- Neonatal Respiratory Health Research
- Animal health and immunology
- Fibroblast Growth Factor Research
- Birth, Development, and Health
- Congenital Anomalies and Fetal Surgery
- Gut microbiota and health
- Congenital Diaphragmatic Hernia Studies
- Breastfeeding Practices and Influences
- Pediatric health and respiratory diseases
Baylor College of Medicine
2022-2025
Children's Nutrition Research Center at Baylor College of Medicine
2021-2023
Agricultural Research Service
2022
Biliary atresia (BA) is a pediatric liver disease that often necessitates parenteral nutrition (PN) to support growth due impaired function. While soy oil lipid emulsions (SLE) are commonly used in PN, they may contribute cholestatic injury. In contrast, mixed (MLE) show promise preventing cholestasis non-BA infants, potentially by restoring bile flow. However, their effectiveness cases of complete duct obstruction, as seen BA, remains uncertain. To explore the potential benefits MLE we...
Necrotizing enterocolitis (NEC) is the leading cause of death caused by gastrointestinal disease in preterm infants. Major risk factors include prematurity, formula feeding, and gut microbial colonization. Microbes have been linked to NEC, yet there no evidence causal species, select probiotics shown reduce NEC incidence In this study, we evaluated effect probiotic Bifidobacterium longum subsp. infantis (BL. infantis), alone combination with a human milk oligosaccharide (HMO)—sialylactose...
Abstract The influence of birth modality (scheduled cesarean or spontaneous vaginal) on the development newborn has been a source controversy in neonatology. impact vs vaginal bile acid and fibroblast growth factor 19 (FGF19) signaling is unknown. Our aim was to determine effect gestational age (preterm term) plasma hormone levels, pool distribution, expression genes acid-FXR-FGF19 pathway, levels FGF19 at day 3 life neonatal pigs. Four sows underwent delivery gestation 105 (n = 2) 114 2;...
Background: Women at risk of preterm birth are routinely administered prenatal doses glucocorticoids to facilitate lung maturation and improve pulmonary outcomes in infants. Additionally, infants often low postnatally for prevention bronchopulmonary dysplasia. However, there is limited understanding about the impact perinatal glucocorticoid exposure on gut liver In pigs, a spike plasma cortisol newborns during parturition. We previously showed pigs that levels positively correlate with...
Abstract The provision of mammary secretions in the form colostrum and mature milk for newborns is an essential survival function that has evolved over millennia mammalian species. Colostrum serves a vital neonates by providing nutrients energy growth as they transition from placental nutrition to oral ingestion more complex macromolecules, including lactose, proteins, triglycerides. also provides critical immune protection colonizing commensal pathogenic microbes supports neonatal immunity...