Hearing loss is associated with poor cognitive performance and incident dementia may contribute to decline. Treating hearing aids ameliorate The purpose of this study was test whether use better performance, if relationship mediated via social isolation and/or depression. Structural equation modelling associations between loss, isolation, depression aid carried out a subsample the UK Biobank data set (n = 164,770) adults aged 40 69 years who completed test. Age, sex, general health...

Healthy hearing depends on sensitive ears and adequate brain processing. Essential aspects of both cognition decline with advancing age, but it is largely unknown how one influences the other. The current standard measure hearing, pure-tone audiogram not very cognitively demanding does predict well most important yet challenging use listening to speech in noisy environments. We analysed data from UK Biobank that asked 40-69 year olds about their assessed ability tests speech-in-noise...

To report population-based prevalence of hearing impairment based on speech recognition in noise testing a large and inclusive sample U.K. adults aged 40 to 69 years. The present study is the first such data. Prevalence tinnitus use aids also reported.

Objective: We explored the relationship between audiogram shape and tinnitus pitch to answer questions arising from neurophysiological models of tinnitus: 'Is dominant associated with edge hearing loss?' such a more robust in people narrow bandwidth or steep sloping Design: A broken-stick fitting objectively quantified slope, degree loss up 16 kHz. Tinnitus was characterized 12 used correlation multiple regression analyses for examining relationships many potentially predictive audiometric...

Previous research has suggested that a substantial proportion of the population are severely affected by tinnitus, however recent data lacking. Furthermore, there is growing evidence perception severity closely related to personality factors such as neuroticism.In subset (N=172,621) large sample >500,000 adults aged 40 69years, (from UK Biobank dataset) we calculated prevalence tinnitus and which perceived bothersome, examined association between putative predisposing factor,...

Objective: Clinical studies indicate increased risk for depression and anxiety among tinnitus patients. However population data are scarce, no have controlled neuroticism. We examined associations between symptoms of in a large UK population, controlling neuroticism, to explore whether as previously reported, fully explains the association anxiety, tinnitus. Design: used Biobank resource. Study sample: 171 728 participants answered hearing questions. Results: Using generalized linear...

The ability to reproducibly match tinnitus loudness and pitch is important research clinical management. Here we examine agreement reliability of matching likeness ratings when using a computer-based method measure the spectrum estimate dominant pitch, tonal or narrowband sounds. Group level data indicated significant effect time between test session 1 2 for matching, likely procedural perceptual learning, which needs be accounted in study design. Pitch rating across multiple frequencies...

Objective: Psychoacoustic measures of tinnitus, in particular dominant tinnitus pitch and its relationship to the shape audiogram, are important determining verifying pathophysiological mechanisms condition. Our previous study postulated that this might vary between different groups people with tinnitus. For a small subset participants narrow bandwidth, was associated audiometric edge, consistent tonotopic reorganization theory. The current objective establish an independent sample. Design:...

Abstract Purpose Vision and hearing impairments are known to increase in middle age. In this study we describe the prevalence of vision impairment dual sensory UK adults aged 40–69 years a very large recently ascertained data set. The associations between impairment, age, sex, socioeconomic status, ethnicity reported. Methods This research was conducted using B iobank R esource, with subsets analysed respect self‐report eye problems glasses use. Better‐eye visual acuity habitually worn...

Objective The impact of dietary factors on tinnitus has received limited research attention, despite being a considerable concern among people with and clinicians. objective was to examine the link between presence severity tinnitus. Design This study used UK Biobank resource, large cross-sectional adults aged 40–69. 171,722 eligible participants were asked questions specific (defined as noises such ringing or buzzing in head ears). Dietary included portions fruit vegetables per day, weekly...

Some forms of tinnitus are likely to be perceptual consequences altered neural activity in the central auditory system triggered by damage periphery. Animal studies report changes evoked responses after noise exposure or ototoxic drugs inferior colliculus and cortex. However, human electrophysiological evidence is rather equivocal: increased, reduced no difference N1/N1m amplitudes latencies participants have been reported. The present study used magnetoencephalography seek for people with...

Individuals with a unilateral severe-to-profound hearing loss, or single-sided deafness, report difficulty listening in many everyday situations despite having access to well-preserved acoustic one ear. The standard of care for deafness available on the UK National Health Service is contra-lateral routing signals aid which transfers sounds from impaired ear non-impaired This has been found improve speech understanding noise when signal-to-noise ratio more favourable at than However,...

It is unclear what the contribution of prenatal versus childhood development for adult cognitive and sensory function age-related decline in function. We examined hearing, vision adulthood according to self-reported birth weight (an index development) height early development). Subsets (N = 37,505 433,390) UK Biobank resource were analysed visual hearing acuity, reaction time fluid IQ. Sensory performance was reassessed after ~4 years 2,438 17,659). In statistical modelling including age,...

To estimate and compare the prevalence of associations between tinnitus sleep difficulties in a sample UK adult cochlear implant users those identified as potential candidates for implantation.The study was conducted using Biobank resource, population-based cohort 40- to 69-year olds. Self-report data on hearing, tinnitus, difficulties, demographic variables were collected from (n = 194) individuals implantation 211). These "candidates" selected based (i) impaired hearing sensitivity,...

Seven-valent pneumococcal conjugate vaccine (PCV7) was introduced to Sweden in 2009 and replaced by non-typeable Haemophilus influenzae protein D (PHiD-CV) or 13-valent PCV (PCV13) from late 2009. A retrospective cohort study assessed the impact of PCVs on otitis media/acute media (OM) children aged ≤5 years (NCT02742753) living Skåne (PCV7 then PHiD-CV) Västra Götalandsregionen PCV13) between 2005 2013 using linked regional national databases. Time-series analyses described differences...

Objectives: To determine population-based risks of adverse effects on hearing and well-being outcomes associated with unilateral impairment. Design: A group 40- to 69-year-old adults (n = 861) who reported being able hear only in one ear having speech reception thresholds (SRTs) noise indicating normal that (SRT N/− ) was selected from the UK Biobank cohort. The participants SRTs either N/N , n 95,514) or symmetrically impaired both ears I/I 17,429) were as comparison groups. Self-reported...

We re-examined a modified emotional Stroop task that included an additional colour-word alongside the word, providing response conflict of traditional task. Negative emotionally salient (i.e. unpleasant') words are claimed to capture attention, producing smaller effect for negative compared neutral words; this phenomenon is called dilution effect. To address previous limitations, study with lexically matched in powered sample 45 participants. Results demonstrated (slower colour-naming...

In Sweden, the 7-valent pneumococcal conjugate vaccine (PCV7) was introduced in 2009 and replaced by non-typeable Haemophilus influenzae protein D (PHiD-CV) or 13-valent PCV (PCV13) from late 2009. We assessed impact of PCVs on rates antibiotic prescribing, tympanostomy tube placement (TTP), healthcare resource utilization direct costs physician-diagnosed otitis media/acute media (OM) children ≤2 years age living Skåne (PCV7 then PHiD-CV) Västra Götalandsregionen (VGR; PCV7 PCV13)....