Xi Chen

ORCID: 0000-0003-1125-8392
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About
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Gastrointestinal Tumor Research and Treatment
  • Helicobacter pylori-related gastroenterology studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Gut microbiota and health
  • Clostridium difficile and Clostridium perfringens research
  • Genetic factors in colorectal cancer
  • interferon and immune responses
  • Gastrointestinal disorders and treatments
  • Neuroblastoma Research and Treatments
  • Cell death mechanisms and regulation
  • Case Reports on Hematomas
  • Pancreatitis Pathology and Treatment

Fujian University of Traditional Chinese Medicine
2024-2025

Zhejiang University
2025

Zhuhai People's Hospital
2024

Jinan University
2024

Background The stimulator of interferon genes (STING) signaling pathway has been demonstrated to propagate the cancer-immunity cycle and remodel tumor microenvironment emerged as an appealing target for cancer immunotherapy. Interest in STING agonist development increased, candidates hold significant promise; however, most are still early stages human clinical trials. We found that ABT-199 activated enhance immunotherapeutic effect, provided a ready-to-use small molecule drug activation....

10.1136/jitc-2024-010889 article EN cc-by-nc-nd Journal for ImmunoTherapy of Cancer 2025-04-01

Rationale: Spontaneous retroperitoneal hematoma (SRH) is a rare but potentially fatal condition, often associated with anticoagulation therapy. With the global prevalence of COVID-19 and widespread use anticoagulants in its management, there an increasing need to recognize serious complications like SRH. This case report aims emphasize importance early recognition intervention SRH patients undergoing therapy, improve patient outcomes reduce mortality. Diagnoses: An 86-year-old male history...

10.1097/md.0000000000041077 article EN cc-by-nc Medicine 2025-01-10

Acute coronary syndrome (ACS) is a predominant cause of mortality, and the prompt precise identification this condition crucial to minimize its impact. Recent research indicates that gut microbiota associated with onset, progression, treatment ACS. To investigate role, we sequenced 38 ACS patients before after percutaneous intervention statin therapy at three time points, examining differential species metabolic pathways. We observed decrease in abundance Parabacteroides , Escherichia...

10.3389/fmicb.2024.1369478 article EN cc-by Frontiers in Microbiology 2024-07-05

Traditionally, endoscopic procedures have been limited to a single–channel device, making it difficult for endoscopists perform submucosal dissection (ESD). As result, several solutions developed, each with its own advantages and disadvantages, including traction devices [1] [2], double-channel endoscopes [3], laparoscopy–endoscopy combined surgery [4], surgical robots [5]. To address these challenges, we fabricated rotatable transparent cap fixed channel that can accommodate instruments.

10.1055/a-2222-6958 article EN cc-by Endoscopy 2024-01-23

10.1002/ueg2.12647 article RO cc-by-nc-nd United European Gastroenterology Journal 2024-09-04
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