- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Acute Myocardial Infarction Research
- Anesthesia and Sedative Agents
- Thermal Regulation in Medicine
- Respiratory Support and Mechanisms
- Heart Failure Treatment and Management
- Opioid Use Disorder Treatment
- Airway Management and Intubation Techniques
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Anesthesia and Pain Management
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Cardiac Imaging and Diagnostics
- Trauma and Emergency Care Studies
- Healthcare Policy and Management
- Pharmaceutical Practices and Patient Outcomes
- Hemodynamic Monitoring and Therapy
- Stroke Rehabilitation and Recovery
- Atrial Fibrillation Management and Outcomes
Indiana University School of Medicine
2016-2025
Indiana University – Purdue University Indianapolis
2016-2025
Indiana University
2018-2024
University School
2024
RELX Group (United States)
2019
Ninewells Hospital
1997-2008
Sparrow Hospital
2001
Background: Studies examining the association between hyperoxia exposure after resuscitation from cardiac arrest and clinical outcomes have reported conflicting results. Our objective was to test hypothesis that early postresuscitation is associated with poor neurological outcome. Methods: This a multicenter prospective cohort study. We included adult patients who were mechanically ventilated received targeted temperature management return of spontaneous circulation. excluded caused by...
Laboratory studies suggest elevated blood pressure after resuscitation from cardiac arrest may be protective; however, clinical data are limited. We sought to test the hypothesis that postresuscitation mean arterial is associated with neurologic outcome.Preplanned analysis of a prospective cohort study.Six academic hospitals in United States.Adult, nontraumatic patients treated targeted temperature management return spontaneous circulation.Mean was measured noninvasively circulation and...
Abstract Healthcare employees were tested for antibodies against severe acute respiratory coronavirus virus 2 (SARS-CoV-2). Among 734 employees, the prevalence of SARS-CoV-2 was 1.6%. Employees with heavy disease 2019 (COVID-19) exposure had similar antibody as those limited or no exposure. Guidelines PPE use seem effective preventing COVID-19 infection in healthcare workers.
We seek to test the efficacy of noninvasive sphenopalatine ganglion block for treatment acute anterior headache in emergency department (ED) using a novel delivery device.We conducted randomized, double-blind, placebo-controlled trial evaluating bupivacaine anesthesia or global-based headache. This study was completed 2 large academic EDs. Bupivacaine normal saline solution delivered intranasally (0.3 mL per side) with Tx360 device. Pain and nausea were measured at 0, 5, 15 minutes by 100-mm...
The rate of bacterial coinfection with SARS-CoV-2 is poorly defined. decision to administer antibiotics early in the course infection depends on likelihood coinfection.We performed a retrospective chart review all patients admitted through emergency department confirmed over 6-week period large healthcare system United States. Blood and respiratory culture results were abstracted adjudicated by multiple authors. primary outcome was bacteremia. We secondarily looked define clinical or...
Background and Objectives: Hospitals clinicians increasingly are reimbursed based on quality of care through financial incentives tied to value-based purchasing. Patient-centered care, measured patient experience surveys, is a key component many incentive programs. We hypothesize that operational aspects such as wait times an important element emergency department (ED) experience. The objectives this paper determine (1) the association between ED (2) whether comments show awareness times....
Sepsis is a leading cause of hospital mortality and there evidence that outcomes vary by patient demographics including race gender. Our objectives were to determine whether the introduction standardized sepsis order set was associated with (1) changes in overall or early antibiotic administration (2) outcome disparities based on
Abstract Background Limited data have described the testing patterns and outcomes of adults (≥18 years) with acute respiratory illness (ARI) in emergency department setting. Methods This prospective cohort study includes patients ARI from a program sponsored by Centers for Disease Control Prevention entitled Respiratory Virus Laboratory Emergency Department Network Surveillance (RESP-LENS) August 2021 until March 2024 (91 hospitals). Patients ARIs were identified weekly electronic...
Abstract Background Patients with COVID‐19 can present to the emergency department (ED) at any point during spectrum of illness, making it difficult predict what level care patient will ultimately require. Admission a ward bed, which is subsequently upgraded within hours an intensive unit (ICU) represents inability appropriately patient's course illness. Predicting patients require ICU 24 would allow admissions be managed more appropriately. Methods This was retrospective study adults...
Background: Identifying low-risk acute heart failure patients safe for discharge from the emergency department is a major unmet need. Methods AND RESULTS: A prospective, observational, multicenter pilot study targeting lower risk to determine whether hsTnT (high-sensitivity troponin T) identifies at low rehospitalization and mortality. was drawn baseline 3 hours. Phone follow-up occurred 30 90 days. The primary end point composite of all-cause mortality, rehospitalization, visits days...
Elderly patients presenting to the emergency department (ED) with nonspecific complaints (NSCs) often undergo troponin testing assess for atypical acute coronary syndrome (ACS). However, rate of ACS and utility in this population is unknown. We sought determine diagnostic yield elderly NSCs.We retrospectively identified all aged ≥ 65 years triaged ED NSCs from January 1, 2017, June 30, 2017. were defined a priori included such as weakness, dizziness, or fatigue. verified provider notes by...
The recent approval and distribution of vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been a major development in the fight current disease 2019 (COVID-19) pandemic. first two approved United States, mRNA-1273, BNT162b2, are both messenger RNA (mRNA) based highly effective immunocompetent persons, but efficacy patients on immunosuppressants has not established. Additionally, data suggests these less likely than people to develop neutralizing antibodies...