Christopher W. Jones
A5050014604- Posttraumatic Stress Disorder Research
- Traumatic Brain Injury Research
- Cardiac Arrest and Resuscitation
- Child Abuse and Trauma
- Migration, Health and Trauma
- Emergency and Acute Care Studies
- Resilience and Mental Health
- Meta-analysis and systematic reviews
- Stress Responses and Cortisol
- Psychosomatic Disorders and Their Treatments
- Trauma and Emergency Care Studies
- Health Systems, Economic Evaluations, Quality of Life
- Traumatic Brain Injury and Neurovascular Disturbances
- Heart Rate Variability and Autonomic Control
- Birth, Development, and Health
- Ethics in Clinical Research
- Maternal Mental Health During Pregnancy and Postpartum
- Child and Adolescent Psychosocial and Emotional Development
- Intensive Care Unit Cognitive Disorders
- Delphi Technique in Research
- Functional Brain Connectivity Studies
- Opioid Use Disorder Treatment
- Homelessness and Social Issues
- Substance Abuse Treatment and Outcomes
- Anesthesia and Neurotoxicity Research
Cooper Medical School of Rowan University
2016-2025
Rowan University
2019-2025
Cooper University Health Care
2019-2024
Fiona Stanley Hospital
2021-2024
Orthopaedic Research Foundation
2024
Curtin University
2023-2024
University of North Carolina at Chapel Hill
2010-2022
McLean Hospital
2021-2022
Emory University
2019-2022
Temple University
2022
Physicians need information on how to use the first available high-sensitivity troponin (hsTnT) assay in United States identify patients at very low risk for 30-day adverse cardiac events (ACE).To determine whether a negative hsTnT 0 and 3 hours following emergency department presentation could less than 1% of ACE.A prospective, observational study 15 departments between 2011 2015 that included individuals 21 years older, presenting with suspected acute coronary syndrome. Of 1690 eligible...
Major negative life events, such as trauma exposure, can play a key role in igniting or exacerbating psychopathology. However, few disorders are diagnosed with respect to precipitating and the of these events unfolding new psychopathology is not well understood. The authors conducted multisite transdiagnostic longitudinal study exposure related mental health outcomes identify neurobiological predictors risk, resilience, different symptom presentations.
Objective: Dissociation, a disruption or discontinuity in psychological functioning, is often linked with worse psychiatric symptoms; however, the prognostic value of dissociation after trauma inconsistent. Determining whether trauma-related uniquely predictive later outcomes would enable early identification at-risk populations. The authors conducted largest prospective longitudinal biomarker study persistent to date determine its capacity for adverse following acute trauma. Methods: All...
Laboratory studies suggest elevated blood pressure after resuscitation from cardiac arrest may be protective; however, clinical data are limited. We sought to test the hypothesis that postresuscitation mean arterial is associated with neurologic outcome.Preplanned analysis of a prospective cohort study.Six academic hospitals in United States.Adult, nontraumatic patients treated targeted temperature management return spontaneous circulation.Mean was measured noninvasively circulation and...
Adverse childhood experiences (ACEs) are associated with mental and physical health risks that, through biological psychosocial pathways, likely span generations. Within an individual, telomere length (TL), established marker of cellular stress aging, is both ACE exposure psychopathology, providing the basis for emerging literature suggesting that TL a biomarker linked to early-life adversity within across The authors tested effect maternal ACEs on trajectory infant social-emotional problems...
Background Among older adults, malnutrition is common, often missed by healthcare providers, and influences recovery from illness or injury. Objective To identify modifiable risk factors associated with in patients. Design Prospective cross‐sectional multicenter study. Setting 3 ED s the South, Northeast, Midwest. Participants Non‐critically ill, English‐speaking adults aged ≥65 years. Measurements Random time block sampling was used to enroll The interview assessed using Mini Nutritional...
Considerable racial/ethnic disparities persist in exposure to life stressors and socioeconomic resources that can directly affect threat neurocircuitry, particularly the amygdala, partially mediates susceptibility adverse posttraumatic outcomes. Limited work date, however, has investigated potential variability amygdala reactivity or connectivity may turn be related outcomes such as post-traumatic stress disorder (PTSD). Participants from AURORA study (n = 283), a multisite longitudinal of...
Abstract Patients exposed to trauma often experience high rates of adverse post-traumatic neuropsychiatric sequelae (APNS). The biological mechanisms promoting APNS are currently unknown, but the microbiota-gut-brain axis offers an avenue understanding as well possibilities for intervention. Microbiome composition after exposure has been poorly examined regarding outcomes. We aimed determine whether gut microbiomes trauma-exposed emergency department patients who develop have dysfunctional...
Publication bias is a major threat to the validity of systematic reviews. Searches clinical trials registries can help identify unpublished trials, though little known about how often these resources are utilized. We assessed usage and results registry searches reported in reviews published general medical journals. This cross-sectional analysis includes data from assessing interventions which were one six journals between July 2012 June 2013. Two authors independently examined each review...
<h3>Importance</h3> A substantial proportion of the 40 million people in US who present to emergency departments (EDs) each year after traumatic events develop posttraumatic stress disorder (PTSD) or major depressive episode (MDE). Accurately identifying patients at high risk ED would facilitate targeting preventive interventions. <h3>Objectives</h3> To and validate a prediction tool based on reports motor vehicle collision predict PTSD MDE 3 months later. <h3>Design, Setting,...
Abstract Visual components of trauma memories are often vividly re-experienced by survivors with deleterious consequences for normal function. Neuroimaging research on has primarily focused threat-processing circuitry as core to trauma-related dysfunction. Conversely, limited attention been given visual which may be particularly relevant posttraumatic stress disorder (PTSD). Prior work suggests that the ventral stream is directly related cognitive and affective disturbances observed in PTSD...
Importance Adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure are common and have higher incidence among socioeconomically disadvantaged populations. Pain, depression, avoidance of trauma reminders, reexperiencing trauma, anxiety, hyperarousal, sleep disruption, nightmares been reported. Wrist-wearable devices with accelerometers capable assessing 24-hour rest-activity characteristics prevalent may utility in measuring these outcomes. Objective To evaluate...
Objectives To characterise current COVID-19-related research activities. Design Cross-sectional analysis. Setting Clinical trials registered with ClinicalTrials.gov testing interventions relevant to COVID-19. Data sources was searched for COVID-19 and related terms identify between 1 December 2019 May 2020 that test the pandemic. Main outcome measures We classified according intervention type, report key trial characteristics including recruitment status, location, funder target enrolment...