A5103062055- Dermatology and Skin Diseases
- Anesthesia and Sedative Agents
- Psoriasis: Treatment and Pathogenesis
- Airway Management and Intubation Techniques
- Skin Protection and Aging
- Anesthesia and Pain Management
- Intensive Care Unit Cognitive Disorders
- Dermatologic Treatments and Research
- Exercise and Physiological Responses
- T-cell and B-cell Immunology
- Wound Healing and Treatments
- Nasolacrimal Duct Obstruction Treatments
- Immune Response and Inflammation
- Glaucoma and retinal disorders
- Anesthesia and Neurotoxicity Research
- Ocular Surface and Contact Lens
First Affiliated Hospital of GuangXi Medical University
2024-2025
Guangxi Medical University
2024-2025
Xiamen University
2021-2024
Dermal adipocyte lineage cells are highly plastic and can undergo reversible differentiation dedifferentiation in response to various stimuli. Using single-cell RNA sequencing of developing or wounded mouse skin, we classify dermal fibroblasts (dFBs) into distinct non-adipogenic adipogenic cell states. Cell trajectory analyses identify IL-1-NF-κB WNT-β-catenin as top signaling pathways that positively negatively associate with adipogenesis, respectively. Upon wounding, activation progenitors...
A combination of opioids with propofol is a popular approach to non-intubated general anaesthesia; however, this method usually results in higher incidence respiratory depression. We compared the esketamine- and fentanyl-induced depression women undergoing abortion surgery or curettage under propofol-based anaesthesia. This study included 176 (aged 18-60 years) scheduled for curettage. Patients were randomized into fentanyl esketamine groups. group received (1 µg/kg) combined intravenously....
Aluminum salt (AS), one of the most commonly used vaccine adjuvants, has immuno-modulatory activity, but how administration AS alone may impact activation skin immune system under inflammatory conditions not been investigated. Here, we studied therapeutic effect injection on two distinct mouse models: an imiquimod (IMQ)-induced psoriasis-like model and MC903 (calcipotriol)—induced atopic dermatitis-like model. We found that a high dose only suppressed IMQ-mediated development T-helper 1...
Opioids are used to suppress cough during fiberoptic bronchoscopy (FOB). However, evidence regarding the optimal dose of remifentanil FOB under ciprofol sedation is limited. This study aimed investigate effective concentration (EC) required responses in elderly patients.
Objective: To evaluate the association of meibomian gland dysfunction (MGD) and body mass index (BMI) in Chinese adults. Methods: A total 2 419 patients were retrospectively recruited between May October 2013 from 33 ocular surface disease clinic China. There 780 males (32.2%) 1 639 females (67.8%), aged 18-89 (46±16) years. BMI value each patient was respectively calculated, divided into underweight, normal weight, overweight obesity groups accordingly. Meibomian gland-related examinations...
<title>Abstract</title> The skin’s immune response to danger signals involves rapid recruitment of neutrophils, but their excessive accumulation leads inflammatory skin diseases, such as psoriasis, and how resident cells tolerate neutrophilic inflammation is poorly understood. Dermal white adipose tissue (dWAT) an emerging component the skin's barrier, its role in controlling remains under-studied. Here, using imiquimod-induced psoriasis mouse model, we observed a dynamic coupling between...
To explore the effect of continuous low-dose infusion esmolamine on intraoperative dosage opioids and awakening quality in general anesthesia pediatric surgeries.A total 100 children (6-8 years age) undergoing surgery under were randomized equally into observation group control group.In group, received an intravenous injection 0.1mg/kg 10 min before induction anesthesia, followed by at 2 μg•kg-1•min-1 until end operation; those infused with same volume normal saline instead manner.The...