Background Multiple studies have attempted to elucidate the relationship between chronic hypoxia and SARS-CoV-2 infection. It seems that high-altitude is associated with lower COVID-19 related mortality incidence rates; nevertheless, all data came from observational studies, being this first one looking into prospectively collected clinical severely ill patients residing at two significantly different altitudes. Methods A prospective cohort, a two-center study among confirmed adult admitted...

Ortiz-Prado, Esteban, Raul Patricio Fernandez Naranjo, Eduardo Vasconez, Katherine Simbaña-Rivera, Trigomar Correa-Sancho, Alex Lister, Manuel Calvopiña, and Ginés Viscor. Analysis of excess mortality data at different altitudes during the COVID-19 outbreak in Ecuador. High Alt Med Biol. 22:406-416, 2021. Background: It has been speculated that living high altitude confers some risk reduction terms SARS-CoV-2 infection, reduced transmissibility, arguable lower COVID-19-related mortality....

Abstract Background The relentless advance of the SARS-CoV-2 virus pandemic has resulted in a significant burden on countries, regardless their socio-economic conditions. infected more than 2.5 million people worldwide, causing to date 150,000 deaths over 210 countries. Objective aim this study was describe trends cases, tests and related novel coronavirus disease (COVID-19) Latin American Caribbean (LAC) Methodology Data were retrieved from WHO-Coronavirus Disease (COVID-2019) situation...

Health systems worldwide rely on health professionals to deliver services and provide framework structures. Considering their opinions about work environment, the public policies that regulate deficiencies of care system are key aspects governance within system. The aim this study was assess perceptions Ecuadorian physicians several performance delivery monitoring locally.A cross-sectional survey performed in a group Ecuador during 2017 using self-selection sampling strategy. participants...

Isolated Indigenous peoples are a group of tribes that live in voluntary isolation remote and mostly inaccessible territories. Together with initial contact, threatened continuously by advancing extractive activities, the absence public policies protection measures State, pressure illegal activities on their Generating multidimensional protect these groups is essential. This commentary shares South America’s perspective matter as it region where most isolated reside.

Background Despite worldwide progress in terms of clean water supply, sanitation, and hygiene knowledge, some middle most low-income countries are still experiencing many diseases transmitted using unsafe the lack sanitation. Methods To understand impact all waterborne (WBD) registered Ecuador. We performed a population-based analysis cases deaths due to WBD Ecuador based on national public databases hospital discharges as proxy incidence, in-hospital mortality, countrywide general mortality...

Introduction: The exponential growth of the SARS-CoV-2 virus transmission during first months 2020 has placed substantial pressure on health systems worldwide. complications derived from novel coronavirus disease (COVID-19) vary in due to comorbidities, sex and age, with more than 50% patients who require some level intensive care developing acute respiratory distress syndrome (ARDS). Areas covered: Various caused by infection have been identified, most lethal being syndrome, likely presence...

Background. The 15q11.1-13.1 duplication, also known as Dup15q syndrome, is a rare congenital disease affecting 1 in 30,000 to 60,000 children worldwide. This condition characterized by the presence of at least one extra copy genetical material within Prader-Willi/Angelman Critical Region (PWACR) referred 15q11.2-q13.1 chromosome. Case Report. Our study presents clinical and features first patient with denovo 15q11.2 interstitial duplication on maternal allele (inv Dup15q) that mimics milder...

Abstract Background The novel human coronavirus, SARS-CoV-2, has affected at least 218 countries worldwide. Some geographical and environmental factors are positively associated with a better or worse prognosis concerning COVID-19 disease lower higher SARS-CoV-2 transmission. High altitude exposure been attack rates; nevertheless, the role of chronic high-altitude on clinical outcome critically ill patients not studied. Objective To compare course outcomes hospitalized in two intensive care...

Abstract Background: Latin America is the most affected region by COVID-19 pandemic in terms of excessive mortality. Diagnostic and health care capabilities are limited this region, deficiencies resulting poor contact tracing, insufficient medical treatment an unprecedented number deaths. One key issues to estimate pandemic's actual impact track deaths as one reliable indicators when SARS-CoV-2 under-diagnosis evident. Objective: This study's objective was attributed based on excess...

Abstract Background Despite worldwide progress in terms of clean water supply, sanitation, and hygiene knowledge, some middle most low-income countries are still experiencing many diseases transmitted using unsafe the lack sanitation. Methods To understand impact all waterborne (WBD) registered Ecuador, we performed an analysis cases deaths related to WBD compute incidence mortality rates. Results We found that mestizo people had greatest morbidity rate (141/100,000) patient followed by...

Abstract BackgroundDespite worldwide progress in terms of clean water supply, sanitation, and hygiene knowledge, some middle most low-income countries are still experiencing many diseases transmitted using unsafe the lack sanitationMethodsTo understand impact all waterborne (WBD) registered Ecuador, we performed an analysis cases deaths related to WBD compute incidence mortality rates.ResultsWe found that mestizo people had greatest morbidity rate (141/100,000) patient followed by indigenous...

At the beginning of COVID-19 pandemic, Ecuador was unprepared for overwhelming number cases. As general population started to see eff ects unproven treatments and medications were sought by try ameliorate impact pandemic. The growing demand a cure, fear dying from COVID-19, lack therapeutic rigour, pushed signifi cant people seek help outside traditional healthcare system. Doctors, pharmacists, patients prescribing or selfmedicating pharmacological products that later shown be ineff ective,...

Background: The novel human coronavirus, SARS-CoV-2, has affected at least 218 countries worldwide. Some geographical and environmental factors are positively associated with a better or worse prognosis concerning COVID-19 disease lower higher SARS-CoV-2 transmission. High altitude exposure been attack rates; nevertheless, the role of chronic high-altitude on clinical outcome critically ill patients not studied.Objective: To compare course outcomes hospitalized in two intensive care units...

Abstract Background: Biomedical and ethnographic studies among indigenous people are common practice in health geographical research. Prior research misconduct has been documented, particularly when obtaining genetic material. The objective of this study was to crossmatch previously published data with the perceptions Waorani peoples about trading their material other biological samples. Methods: We conducted a mixed methods design using tailored 15-item questionnaire 72 participants...

Abstract Background: Biomedical and ethnographic studies among indigenous people are common practice in health geographical research. Prior research misconduct has been documented, particularly when obtaining genetic material. The objective of this study was to crossmatch previously published data with the perceptions Waorani peoples about trading their material other biological samples. Methods: We conducted a mixed methods design using tailored 15-item questionnaire 72 participants...

Abstract Background Biomedical and ethnographic studies among indigenous people are common practice in health geographical research. Prior research misconduct has been documented, particularly when obtaining genetic material. The objective of this study was to crossmatch previously published data with the perceptions Waorani peoples about trading their material other biological samples. Methods We conducted a mixed methods design using tailored 15-item questionnaire in-depth interviews 72...

Background: The COVID-19 pandemic has been deadly globally; however, the most lethal outbreak worldwide occurred in Ecuador. Our work aims to highlight pandemic's impact on affected countries due terms of excess deaths per capita and day. Methodology: An ecological study all-cause mortality recorded Ecuador during year 2020. To calculate total death relative historical average for same dates 2017, 2018 2019. A Poisson fitting analysis was used identify trends officially all-caused those...