A5030756167- Advancements in Transdermal Drug Delivery
- Bee Products Chemical Analysis
- melanin and skin pigmentation
- Essential Oils and Antimicrobial Activity
- Skin Protection and Aging
- Dermatology and Skin Diseases
- Acne and Rosacea Treatments and Effects
- Curcumin's Biomedical Applications
- Antimicrobial agents and applications
- Lipid Membrane Structure and Behavior
- Nanoparticle-Based Drug Delivery
- Inflammatory Biomarkers in Disease Prognosis
- Diabetes Treatment and Management
- Adipokines, Inflammation, and Metabolic Diseases
- Advanced Welding Techniques Analysis
- Nutritional Studies and Diet
- Neuropeptides and Animal Physiology
- Ocular Surface and Contact Lens
- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Phenothiazines and Benzothiazines Synthesis and Activities
- Proteins in Food Systems
- Allergic Rhinitis and Sensitization
- S100 Proteins and Annexins
- Titanium Alloys Microstructure and Properties
Hormozgan University of Medical Sciences
2022-2025
Shaheed Rajaei Cardiovascular Medical and Research Center
2025
Mazandaran University of Medical Sciences
2020-2023
Abstract Background Metabolic Syndrome (MetS) is characterized by the co-occurrence of various metabolic risk factors, significantly increasing cardiovascular diseases (CVD) and type 2 diabetes (T2DM). This study investigates potential hematological indices, specifically neutrophil to high-density lipoprotein cholesterol ratio (NHR) lymphocyte (LHR), as predictors MetS in a population from southern Iran. Methods Utilizing baseline data Bandare-Kong Non-Communicable Diseases (BKNCD) Cohort,...
Abstract Purposes Calcium channel blockers, such as diltiazem (DLZ), are important drugs for wound repair treatment. This current study used an ultrasonic method to increase the cutaneous delivery of (DLZ) niosomes. Methods The impact cholesterol:surfactant ratio on DLZ-loaded niosome formulations was investigated. Differential scanning calorimetry (DSC), powder X-ray diffraction (PXRD), electron microscopy (SEM), attenuated total reflectance-Fourier transform infrared (ATR-FTIR)...
Abstract The therapeutic effectiveness of a chitosan encapsulated bacteriophage cocktail as smart biocontrol agent was evaluated in this study to be used preventative and treatment option for gastrointestinal infections. To evaluate the effect formulation on infection, rats were infected with Salmonella enterica , Shigella flexneri Escherichia coli . weighed their stools cultured. results showed that group which had did not lose weight after 3 days significantly lower changes. Weight loss...
Essential oils have been proposed as promising non-toxic transdermal permeation enhancers. Their use is limited because of their low water solubility. The nanotechnology-based strategies one the ways to overcome this limitation. This study aimed explore enhancing capability cumin essential oil in nanoemulgel systems containing diclofenac sodium. Cumin nanoemulsion was produced by high-pressure homogenization technique. formulation optimized changing HLB values a range 9.65-16.7 using...
In the current study, an ultrasonic approach (as green method) was utilized to prepared kojic acid niosome (kojisome) which aimed increase dermal delivery and improving anti-melanogenesis properties. The study's findings demonstrated that increasing cholesterol enhanced mean particle size from 68.333 ± 5.686 nm 325.000 15.099 entrapment efficiency 0% 39.341 4.126% of kojisome. Cholesterol may enhance number rigidity bilayers induced a enhancement efficiency. skin permeability test revealed...
Purpose: Foodborne diseases are still a serious problem in public health and natural compounds being widely considered for their potential industrial protective additive food products. Origanum vulgare L. has been known as an antimicrobial effective herb. This present study was carried out to examine the effect of O. essential oil nanoemulsion comparison with conventional emulsion. Methods: The obtained by hydrodistillation, analyzed GC-Mass formulated improve water dispersion high-energy...
Purpose: The Objective of the present investigation was to enhance skin delivery vitamin A (Vit A) via producing solid lipid nanoparticles (SLNs) through ultrasonication technique. Methods: For achieving optimal delivery, impacts two surfactants ratio Tween80:Span80 on (NPs) features and respective functions were examined. Powder X-ray diffractometer (PXRD), photon correlation spectroscopy, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), transmission electron...
This study reports on the synthesis of Mn1 - xZnxFe2O4 (Mn, Zn ferrite) magnetic nanoparticles (MNPs) as drug delivery carriers for effective therapeutic outcomes. The MNPs were prepared using coprecipitation method, and their properties investigated based composition. Among compositions tested, Mn0.8Zn0.2Fe2O4 exhibited superparamagnetic with a saturation magnetization moment 34.6 emu/g at room temperature (25°C). To enhance water solubility curcumin (Cur), known its hydrophobic nature, it...
Depression is a serious mental health disorder that can deeply affect person's quality of life, and the importance treatment for depression cannot be overstated. The aim this study to compare ultrasonication procedure as green method thin film hydration technique conventional way preparation niosome increase venlafaxine HCl brain delivery investigate BDNF (Brain-derived neurotrophic factor) gene expression. Both approaches provided well-defined sphere particles; however, (ultrasonication)...
Background: Metabolic syndrome (MetS) is a complex disorder characterized by cluster of metabolic risk factors. Recent research highlights the gut microbiome’s role in regulation, suggesting that modulation through probiotics, prebiotics, and synbiotics may provide novel approach to managing MetS. This umbrella review aims integrate insights from existing meta-analyses explore how changes microbiota influence key body measurement indicators individuals with Methods: A systematic search...
The local treatment of kojic acid (KA) as a tyrosinase inhibitor results in inadequate skin absorption and number side effects. current study aims to maximize KA delivery. To produce KA-hydrogel, 1% was injected into Chitosan/alginate hydrogel. impacts biopolymer proportion on the KA-hydrogel preparations were investigated. Swelling analysis, weight loss differential scanning calorimetry (DSC), electron microscopy (SEM), UV spectroscopy, attenuated total reflectance-Fourier transform...
The possibility of controlling periorbital hyperpigmentation disorders is one the most important research goals in cosmetic preparations. In current investigation, 1% vitamin K (Vit K) was incorporated into a Chitosan/alginate hydrogel which aimed to increase dermal delivery and anti-pigmentation effect. Vit K-hydrogel evaluated using several different tests, including volume expansion/contraction analysis, differential scanning calorimetry (DSC), electron microscopy (SEM), ultraviolet (UV)...
Terbinafine (TER) is a promising candidate medication for the topical treatment of fungal infections. However, its solubility in water and skin permeability are limited. To overcome these limitations, niosome niosomal gel was developed. The impact cholesterol:surfactants on terbinafine incorporated (terbinasome) preparations examined. Differential scanning calorimetry (DSC), photon correlation spectroscopy (PCS), electron microscopy (SEM), attenuated total reflectance-Fourier transform...
Background: The purpose of the current work was to manufacture vitamin A (Vit A) niosome and solid lipid nanoparticle (SLN) using an ultrasonic approach evaluate its effect on wound healing. Methods: nanoparticles were prepared through ultrasonication technique characterized by dynamic light scattering (DLS), transmission electron microscopy (TEM). Further, evaluated for their various parameters such as pH, viscosity, spreadability, stability, in-vitro drug release study, cytotoxicity,...
Purpose: In the present research, a green technique (an ultrasonic method) was used to synthesize menadione sodium bisulfite (MSB) niosome (Menasome) which is improve dermal delivery and increase anti-melanogenesis activities. Methods: Various cholesterol: surfactant (Chol: Sur) ratios were investigated optimize Menasomes. Photon correlation spectroscopy, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR), transmission electron microscopy (TEM), differential...