A5029562650- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Urinary Tract Infections Management
- Telemedicine and Telehealth Implementation
- Bacterial Identification and Susceptibility Testing
- Diverse Musicological Studies
- Diverse Educational Innovations Studies
- Noise Effects and Management
- Social Capital and Networks
- Opinion Dynamics and Social Influence
- Palliative Care and End-of-Life Issues
- Complex Network Analysis Techniques
- Youth Development and Social Support
- Cardiac, Anesthesia and Surgical Outcomes
- Kidney Stones and Urolithiasis Treatments
- Streptococcal Infections and Treatments
- Blood Pressure and Hypertension Studies
- Machine Learning in Bioinformatics
- Metabolism, Diabetes, and Cancer
- Renin-Angiotensin System Studies
- Renal and Vascular Pathologies
- Regional Development and Policy
- Image Processing Techniques and Applications
- Human Mobility and Location-Based Analysis
- Acute Kidney Injury Research
Iowa City VA Health Care System
2023-2025
University of Iowa
2017-2024
University of Iowa Hospitals and Clinics
2023-2024
Iowa City VA Medical Center
2024
Oregon Medical Research Center
2024
University of Pittsburgh
2024
Communities In Schools of Orange County
2024
New York Proton Center
2024
Lindsay Unified School District
2024
New York University
2022
Importance Oral non–β-lactam antibiotics are commonly used for empirical therapy of Staphylococcus aureus infections, especially in outpatient settings. However, little is known about potential geographic heterogeneity and temporal trends the prevalence S resistance to non–β-lactams US. Objective To characterize spatiotemporal among community-onset including regional variation rates geographical multidrug resistance. Design, Setting, Participants This cross-sectional study data from Veterans...
Abstract A central line of inquiry into the sources generalized trust concerns how particularized (trust in known others) extends to (default expectations about trustworthiness people general). While we know that there is considerable cross-national variability strength relationship between and trust, little contextual factors shape degree which spills over more diffuse forms trust. We argue collectivism plays a key role extension The nature social interactions low societies conducive...
Importance Acute kidney injury (AKI) complicates 20% to 25% of hospital admissions and is associated with long-term mortality, especially from cardiovascular disease. Lower systolic blood pressure (SBP) following AKI may be lower but potentially at the cost higher short-term complications. Objective To determine associations SBP mortality readmissions AKI, whether time discharge affects these associations. Design, Setting, Participants This retrospective cohort study adults during a...
Abstract Background Post-procedural antimicrobial prophylaxis is not recommended by professional guidelines but still commonly prescribed and can lead to patient harm. The goal of this multicenter pilot intervention trial was encourage less frequent use post-procedural antimicrobials after common endoscopic urologic procedures.Table 1.Characteristics patients across the 3 participating hospitals during both baseline periods Methods We evaluated a bundled using pre-post, quasi-experimental...
Abstract Background While the use of cumulative susceptibility reports, antibiograms, is recommended for improved empiric therapy and antibiotic stewardship, predictive ability antibiograms has not been well-studied. enhanced have shown to better capture variation in profiles by characteristics such as infection site or patient age, potential seasonal spatial assessed important predicting likelihood susceptibility. Methods Utilizing Staphylococcus aureus isolates obtained outpatient settings...
Nd0.5Sr0.5MnO3 nanoparticles with average sizes of 32-1000 nm in diameter were prepared by sol-gel method. The synthesized characterized using X-ray diffraction, high- resolution transmission microscopy, scanning electron and vibrating sample magnetometer. All samples have the single-phase orthorhombic structure, grain size increases increase annealing temperature. A charge ordering (CO) transition at T(CO) a ferromagnetic-paramagnetic Tc observed 1000 nanoparticles. With decrease particle...
Automatic audio-visual urban traffic understanding is a growing area of research with many potential applications value to industry, academia, and the public sector. Yet, lack well-curated resources for training evaluating models in this hinders their development. To address we present curated dataset, Urban Sound & Sight (Urbansas), developed investigating detection localization sounding vehicles wild. Urbansas consists 12 hours unlabeled data along 3 manually annotated data, including...
Background: Machine-learning (ML) models, such as neural networks (NNs), have been proposed to predict antimicrobial susceptibility at the patient level while incorporating patient-level information from electronic medical record (EMR) systems. However, NNs often do not perform well in predicting rare outcomes, carbapenem resistance. We aimed apply a novel multitask NN create personalized antibiograms for individual patients with Escherichia coli clinical isolates resistance (AMR) four major...
Abstract Objective: Post-procedural antimicrobial prophylaxis is not recommended by professional guidelines but commonly prescribed. We sought to reduce use of post-procedural antimicrobials after common endoscopic urologic procedures. Design: A before-after, quasi-experimental trial with a baseline (July 2020–June 2022), an implementation and intervention period (August 2022–July 2023). Setting: Three participating medical centers. Intervention: assessed the effect bundled on excess ( ie ,...
Simultaneous liver-kidney transplant (SLK) allocation policy in the United States was revised August 2017, reducing access for liver candidates with sustained acute kidney injury (sAKI) and potentially adversely impacting vulnerable populations whose true renal function is overestimated by commonly used estimation equations.
Novel ST398 methicillin susceptible Staphylococcus aureus (MSSA) in the United States was first observed New York City (2004-2007); its diffusion across country resulted changing treatment options. Utilizing outpatient antimicrobial susceptibility data from Veterans Health Administration 2010 to 2019, spatiotemporal prevalence of potential MSSA is documented.
Sociological and urban studies have consistently reported that human behavior exhibits a discernible correlation with population size, following power-law function. Individuals residing in larger communities exhibit significantly higher levels of activity contrast to their counterparts smaller communities. However, the underlying processes responsible for such behavioral patterns remain unclear. The authors propose organizational crowding tends generate competitive pressure results social...
Abstract Using data from the Veterans’ Health Administration 2010 to 2019, we examined distribution and prevalence of community-acquired phenotypic extended-spectrum β-lactamase (ESBL) E. coli in United States. ESBL slowly increased during study period, cluster analysis showed clustering both urban rural locations.
OBJECTIVES/GOALS: Our objective is to develop a Telenephrology dashboard for the 150,000 Veterans that obtain care through Iowa City Affairs Health Care System. goal create comprehensive and user-friendly tool monitoring kidney health facilitating remote nephrology consultations. METHODS/STUDY POPULATION: We structured our intervention according five stages of human-centered design: (1) Empathize, (2) Define, (3) Ideate, (4) Prototype (5) Test. During empathy stage, principal investigator...
2-deoxyglucose (2-DG), targeting Hexokinase I (HKI) to inhibit glycolysis in cancer cells, has inspired drug design. Increasing evidence suggests that its phosphorylated form, 2-deoxyglucose-6-phosphate (2-DG-6-P), may HKI more effectively, highlighting the need understand molecular mechanisms behind this effect. Using simulations, we examined interactions between and substrates—glucose (G) glucose-6-phosphate (G-6-P)—and inhibitors—2-DG 2-DG-6-P. G G-6-P showed stable with HKI, involving...
Abstract Background Oral non-beta-lactam antibiotics are commonly used for empiric therapy of Staphylococcus aureus infections, especially in outpatient settings. However, little is known about geographic heterogeneity the prevalence and temporal trends antibiotic resistance among different regions US. We aimed to characterize spatiotemporal patterns drug-resistance S. using nationwide surveillance data from Veterans Health Administration (VHA) system. Methods Utilizing a dataset 383,514...
Griffin, Benjamin R.; Sarrazin, Mary V.; Yamada, Masaaki; Shi, Qianyi; Sambharia, Meenakshi; Swee, Melissa L.; Jalal, Diana I. Author Information