G. Kyriakakis
A5067921933- Magnetic confinement fusion research
- Ionosphere and magnetosphere dynamics
- Fusion materials and technologies
- Laser-induced spectroscopy and plasma
- Superconducting Materials and Applications
- Autism Spectrum Disorder Research
- Plasma Diagnostics and Applications
- Melanoma and MAPK Pathways
- Cutaneous Melanoma Detection and Management
- Child Development and Digital Technology
- Solar and Space Plasma Dynamics
- Atomic and Molecular Physics
- EEG and Brain-Computer Interfaces
- Laser-Ablation Synthesis of Nanoparticles
- Diamond and Carbon-based Materials Research
- melanin and skin pigmentation
- Particle accelerators and beam dynamics
- Laser Material Processing Techniques
- Polysaccharides Composition and Applications
- Drug-Induced Adverse Reactions
- Nuclear reactor physics and engineering
- Food composition and properties
- Immune Cell Function and Interaction
- Neuroscience and Music Perception
- CAR-T cell therapy research
Laiko General Hospital of Athens
2022-2025
National and Kapodistrian University of Athens
2022-2025
Medway School of Pharmacy
2020
University of Kent
2020
Agricultural University of Athens
2016
National Technical University of Athens
2015
National Centre of Scientific Research "Demokritos"
1992-2001
Max Planck Institute for Plasma Physics
1992
ABSTRACT Background Immune‐related eosinophilia has emerged as an adverse event associated with immune checkpoint inhibitors (ICIs). Its prevalence, severity, duration, clinical significance, diagnostic approach, and management remain unexplored. Methods We conducted a retrospective review of melanoma patient records at university referral center. Our analysis encompassed the incidence eosinophilia, baseline disease characteristics, treatment modalities, peak eosinophil counts, symptoms,...
Density limit investigations on ASDEX have been performed under a variety of conditions: ohmically heated and neutral injection plasmas in H2, D2 He studied different divertor configurations, after various wall coating procedures, with gas puff pellet fuelling, confinement regimes their characteristically density profiles. A detailed description the parametric dependence limit, which all cases is disruptive given. This shown to be at plasma edge. Therefore, highest densities corresponding...
The closed ASDEX Upgrade Divertor II, `LYRA', is capable of handling heating powers up to 20 MW or P/R 12 MW/m, owing a reduction the maximum heat flux target plates by more than factor 2 compared with open I. This caused high radiative losses from carbon and hydrogen inside divertor region in agreement B2-EIRENE modelling predictions. At medium densities H mode, type I ELM behaviour shows no dependence on method (NBI, ICRH). Upgrade-JET dimensionless identity experiments showed...
Ion and electron temperature profiles in conventional L H mode on ASDEX Upgrade are generally stiff limited by a critical gradient length ∇T/T as given ion (ITG) driven turbulence. ECRH experiments indicate that (Te) also stiff, predicted turbulence with streamers. Accordingly, the core edge temperatures proportional to each other plasma energy is pedestal pressure for fixed density profiles. Density not confinement improves peaking. Medium triangularity shapes (δ<0.45) show strongly...
Densities achievable in ASDEX Upgrade discharges are restricted by a disruptive limit the L-mode caused an edge-power imbalance which is linking divertor detachment, Marfe formation and separatrix density. The attainable average densities depend then on internal particle sources core transport can exceed empirical Greenwald
This study primarily aimed to generate real-world evidence (RWE) on the profile and first-line treatment (1LT) patterns of patients with advanced (unresectable Stage III/metastatic) cutaneous melanoma initiated immuno-oncology (IO)- or targeted therapy (TT)-based 1LT between 1 January 2015 2018 (index period), in routine settings Greece. was a multicenter, retrospective chart review study. Eligible consented (unless deceased, for whom consent waived by hospital) were consecutively included...
e21528 Background: Immune-related eosinophilia (irEo) has been described as an adverse event of immune checkpoint inhibitors (ICI), but its rate, severity, duration, clinical significance, diagnostic approach, and management have not analysed. In the present study we analyse these features in patients with melanoma. Methods: We reviewed files advanced/metastatic melanoma treated ICI-based regimens a tertiary university referral centre, to describe rate eosinophilia, along baseline disease...