A5052773239- SARS-CoV-2 and COVID-19 Research
- Pharmaceutical studies and practices
- Pharmacovigilance and Adverse Drug Reactions
- Viral Infections and Immunology Research
- Management, Economics, and Public Policy
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pediatric Pain Management Techniques
- Diverse academic and cultural studies
- Family and Patient Care in Intensive Care Units
- Pharmacogenetics and Drug Metabolism
- Epilepsy research and treatment
- Inflammatory mediators and NSAID effects
- Child and Adolescent Health
- Syphilis Diagnosis and Treatment
- Vaccine Coverage and Hesitancy
- Electroconvulsive Therapy Studies
- Infectious Diseases and Tuberculosis
- Bipolar Disorder and Treatment
- HIV Research and Treatment
- Viral gastroenteritis research and epidemiology
- Pharmaceutical Practices and Patient Outcomes
- Gastroesophageal reflux and treatments
- Archaeological and Historical Studies
- Schizophrenia research and treatment
- Pericarditis and Cardiac Tamponade
Arcispedale Sant'Anna
2022-2024
Italian Medicines Agency
2020-2023
University of Ferrara
2012-2022
St. Anna Hospital
2009
Background Myocarditis and pericarditis following the Coronavirus Disease 2019 (COVID-19) mRNA vaccines administration have been reported, but their frequency is still uncertain in younger population. This study investigated association between Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) vaccines, BNT162b2, mRNA-1273 myocarditis/pericarditis population of vaccinated persons aged 12 to 39 years Italy. Methods findings We conducted a self-controlled case series (SCCS) using national data...
Co-infections in critically ill patients hospitalized for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have an important impact on the outcome of disease 2019 (COVID-19). We compared microbial isolations found COVID-19 intensive care unit (ICU) with those a non-COVID-19 ICU from 22 February to 30 April 2020 and same period 2019. considered blood, urine or specimens obtained bronchoalveolar lavage (BAL) bronchial aspirate (BASP), collected all admitted ICUs without...
Considering the clinical significance for myocarditis and pericarditis after immunization with mRNA COVID-19 vaccines, present pharmacovigilance study aimed to describe these events reported vaccines in Vaccine Adverse Events Reporting System (VAERS). From 1990 July 2021, were most common suspected related cases of and/or (myocarditis: N = 1,165; 64.0%; pericarditis: 743; 55.1%), followed by smallpox 222; 12.2%; 200; 14.8%). We assessed all through case definition classification Brighton...
Abstract Objectives To investigate the association between SARS-CoV-2 mRNA vaccines, BNT162b2 and mRNA-1273, myocarditis/pericarditis. Design Self-Controlled Case Series study (SCCS) using national data on COVID-19 vaccination emergency care/hospital admissions. Setting Italian Regions (Lombardia, Friuli Venezia Giulia, Veneto, Lazio). Participants 2,861,809 individuals, aged 12-39 years, vaccinated with first doses of vaccines (2,405,759 456,050 mRNA-1273) 27 December 2020 30 September...
To assess the extent of off-label drug use and occurrence suspected adverse reactions (ADRs) among paediatric patients in Italian hospitals.
Gallerani M, Imberti D, Mari E, Marra A, Manfredini R. Risperidone and pulmonary embolism: a harmful association? Case series review of the literature. Objective: is an atypical antipsychotic drug used to treat number psychiatric diseases, such as schizophrenia, schizoaffective bipolar disorders irritability in children with autism. Moreover, it also often administered for short-term treatment persistent aggression people moderate-to-severe Alzheimer's dementia. A possible association...
The purpose of TheShinISS-Vax|Flu study is to examine the association between influenza vaccines and adverse events requiring hospital admission or emergency care during vaccination campaigns 2021/2022 2022/2023 in Italy. This a Self-Controlled Case Series multiregional using linked routinely collected data from regional healthcare databases participating regions. Study participants will be persons aged ≥6 months, unvaccinated who have received vaccine seasons Italy experienced outcome...
Abstract Reporting and analysis of Adverse Events Following Immunization (AEFIs) are the cornerstones vaccine safety surveillance prompting causality assessment signal detection. This paper describes impact Italian Pharmacovigilance System vaccines over a 10-year period (2008–2017). The reporting rate (RR) per all distributed dose was calculated. Serious AEFIs assessments for fatal cases were described. main results from detection reported. During study period, 46,430 reported with an...
Vaccine vigilance implies the collection, evaluation, analysis and communication of adverse events following immunization (AEFI) is a useful tool for vaccine monitoring allowing, even after approval marketing, to check its safety/tolerability. The multiregional project "Active surveillance reactions", joined by AUSL Ferrara, aimed at making parents children, who have undergone least one vaccination provided regional calendar in first 24 months life, aware reporting any AEFI via mobile...
Novel antidiabetic drugs have the ability to produce anti-inflammatory effects regardless of their glucose-lowering action. For this reason, these molecules (including GLP-1 RAs and DPP-4is) were hypothesized be effective against COVID-19, which is characterized by cytokines hyperactivity multiorgan inflammation. The aim our work explore potential protective role DPP-4is in COVID-19 (with disease intended a model an acute stressor) non-COVID-19 patients over two-year observation period....