A5101819870- COVID-19 Clinical Research Studies
- Inflammatory Bowel Disease
- COVID-19 and healthcare impacts
- Diverticular Disease and Complications
- Gastrointestinal disorders and treatments
- Microscopic Colitis
- Cardiac pacing and defibrillation studies
- Liver Disease Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Helicobacter pylori-related gastroenterology studies
- Gallbladder and Bile Duct Disorders
- Pain Management and Treatment
- Colorectal Cancer Screening and Detection
- Pancreatitis Pathology and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Biliary and Gastrointestinal Fistulas
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Effects of Radiation Exposure
- Heart Failure Treatment and Management
- COVID-19 diagnosis using AI
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Esophageal and GI Pathology
University of Ferrara
2021-2025
Ospedale Papa Giovanni XXIII
2015-2025
Azienda Unità Sanitaria Locale di Ferrara
2022-2024
Università Campus Bio-Medico
2013-2022
Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione
2021-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2022
Arcispedale Sant'Anna
2021-2022
Fox Chase Cancer Center
2021
Sociedad Española de Medicina Interna
2020
University of Trieste
2020
See editorial on page 36. Since December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) responsible for disease 2019 (COVID-19) has caused a pandemic, with more than 350,000 cases and 15,000 fatalities reported worldwide so far (https://www.healthmap.org/covid-19/). The first case series from Wuhan population, describing clinical characteristics of SARS-CoV-2 infection in China, were recently published.1Guan W.-J. et al.N Engl J Med. 2020; 382: 1708-1720Crossref...
Summary Background : Although bowel ultrasound is a widely accepted diagnostic tool in diseases, its value as the primary imaging procedure patients with symptoms/signs suggestive of inflammatory disorders still unclear. Aim To investigate accuracy compared barium X‐ray studies, computed tomography, endoscopy and surgery initial assessment disorders. Methods Four hundred eighty‐seven hospitalized consecutively for symptoms or signs disorder between December 1999 March 2002 were initially...
<h3>Objectives:</h3> Autologous haematopoietic stem cell transplantation (HSCT) with CD34<sup>+</sup> selection has recently been used in the treatment of refractory Crohn's disease, showing good safety and promising efficacy. We investigated efficacy HSCT unselected peripheral blood cells (PBSCs) moderate–severe disease. <h3>Patients:</h3> Four patients (three male, one female; age range 26–45 years) active disease (median Disease Activity Index (CDAI) 319, 272–345), or intolerant to...
OBJECTIVES: Mucosal healing has been proposed as an important sign of the efficacy medical treatment inflammatory bowel disease; however, direct evidence in ulcerative colitis (UC) is scarce. We evaluated usefulness colonoscopy and ultrasound (US) indexes response to short-term therapy predictors subsequent outcome UC. METHODS: A total 83 patients with moderate-to-severe UC were recruited; endoscopic US severity was graded 0–3 at entry according validated scores. Of recruited patients, 74,...
See editorial on page 36. Up to 20% of health care personnel (HCP) were found be infected with coronavirus disease (COVID-19)1Lancet. 2020; 395: 922Abstract Full Text PDF Scopus (853) Google Scholar in the outbreak northern Italy.2Dipartimento della Protezione Civile.http://www.protezionecivile.gov.it/media-comunicazione/comunicati-stampaGoogle Recommendations patient and HCP protection have been made, such as postponing procedures, triage, use personal protective equipment (PPE), creation...
Necroptosis is a recently described Caspase 8-independent method of cell death that denotes organized cellular necrosis. The roles RIP1 and RIP3 in mediating hepatocyte from acute liver injury are incompletely defined. Effects necroptosis blockade were studied by separately targeting diverse murine models injury. Blockade had disparate effects on disease outcome depending the precise etiology component necrosome targeted. In ConA-induced autoimmune hepatitis, deletion was protective, whereas...
Although evidence suggests frequent gastrointestinal (GI) involvement during coronavirus disease 2019 (COVID-19), endoscopic findings are scarcely reported.
Inflammatory bowel diseases (IBDs) are associated with pathologic findings in the liver and biliary tract. Ultrasonography (US) represents a noninvasive means to study hepatobiliary abnormalities. This evaluated prevalence of US changes their relationship clinical variables large IBD patient population followed single center.Five hundred eighty-three consecutive patients were studied US. After excluding preexisting acute or chronic hepatitis, metabolic disorders, obesity, 511 investigated...
Acid-suppressive medications are commonly used in hospitalized patients, but, to date, little is known about the overall use of these drugs hospital setting.To evaluate appropriateness acid-suppressive therapy a large teaching northern Italy, and fall-out prescription general practice.The antisecretory agents was monitored for 1 month adult patients consecutively admitted L. Sacco University Hospital by reviewing their clinical charts. The each reviewed jointly two consultant...
The risk for gallstones (GD) in inflammatory bowel diseases and the factors responsible this complication have not been well established. We studied incidence of GD a cohort Crohn's disease (CD) ulcerative colitis (UC) patients investigated related factors. A case-controlled study was carried out. population included 634 (IBD) (429 CD, 205 UC) age-matched, sex-matched, body mass index (BMI)-matched controls free at enrollment, who were followed mean 7.2 years (range, 5-11 years).The...
Perianal and rectovaginal fistulae are common complications in Crohn's disease. Magnetic resonance imaging (MRI) endoanal ultrasound used for perianal abscesses, but both methods require expensive equipment experienced investigators. Transperineal may represent another method of detecting We investigated disease using transperineal compared the findings with results as reference standard.A total 46 patients and/or or anovulvar underwent, ultrasound, on same day. was performed regular convex...
Etanercept is a tumour necrosis factor antagonist with anti-inflammatory effects. The aim of our study was to evaluate, for the first time, therapeutic efficacy in vivo inhibition TNF-alpha an experimental model periodontitis.Periodontitis induced adult male Sprague-Dawley rats by placing nylon thread ligature around lower 1st molars. administered at dose 5 mg kg-1, s.c., after placement ligature.Periodontitis resulted inflammatory process characterized oedema, neutrophil infiltration and...
Spinal cord stimulation (SCS) is believed to be effective in treating refractory angina. The need for SCS-related chest paresthesia, however, has hitherto made impossible placebo-controlled trials. Subliminal (non paresthesic) SCS, might also on anginal pain. In this trial we compared subliminal SCS with paresthesic and sham SCS. Twenty-five angina patients, who had never received before, underwent device implantation were randomized three groups: (group PS; n=10), SS; n=7) or "sham" NS;...
Mesenteric adipose tissue hypertrophy is a frequent sonographic finding in Crohn's disease (CD). This study assessed its prevalence, the correlation with degree of clinical or biochemical activity disease, and impact on outcome CD patients.In all, 185 consecutive patients underwent bowel ultrasound to assess presence mesenteric fat alteration as well thickness echopattern wall, site extent CD, stenosis, fistulas, abscesses. Clinical parameters were also assessed. Multiple logistic regression...
Mucosal healing (MH) after short-term medical treatment is being considered as an important step in the therapeutic work-up of inflammatory bowel disorder (IBD) patients due to potential prognostic role MH predicting disease outcome. However, IBD are reluctant be re-endoscoped during follow-up; therefore, there a need for non-invasive alternative index which can replace endoscopy clinical practice. We evaluated ultrasound (US) surrogate colonoscopy series consecutive with active ulcerative...
Recurrences after surgery for Crohn's disease are frequent and unpredictable. To date, there is little agreement as to which factors increase a patient risk of early recurrence.To assess whether the post-operative behaviour diseased bowel walls, determined by ultrasound, may be useful predictor relapse.A total 127 patients were monitored means ultrasound well clinical laboratory evaluations median follow-up 41.0 months. Bowel wall thickness loops measured at during was compared with...
Heart rate variability (HRV) refers to the variations between consecutive heartbeats, which depend on continuous modulation of sympathetic and parasympathetic branches autonomic nervous system. HRV has been shown be effective as a predictor risk after myocardial infarction an early warning sign diabetic neuropathy, in cardiology setting is now recognized useful tool for risk-stratification hospital admission discharge. Recent evidences suggest that analysis might predict complications even...
Analyzing the risk factors that predict readmissions can potentially lead to more individualized patient care. The 11-factor modified frailty index is a valuable tool for predicting postoperative outcomes following surgery. objective of this study determine whether effectively within 90 days after lung resection surgery in cancer patients single health care institution.
Abdominal wall wound dehiscence with mesh exposure is a dangerous adverse event an incidence of 0.4-1.2% and mortality rate up to 25%. To date, there are no standard protocols for the optimal duration negative pressure therapy instillation (NPWTi) specific clinical settings decision treat polypropylene infection NPWTi has only been made in rare case reports. Moreover, recent studies show contrasting results regarding reduction hospital stay abdominal exposed mesh, treated dwell time or...