Luca De Luca

ORCID: 0000-0002-3290-3103
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About
Contact & Profiles
Research Areas
  • Gallbladder and Bile Duct Disorders
  • Pancreatic and Hepatic Oncology Research
  • Esophageal and GI Pathology
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Colorectal Cancer Screening and Detection
  • Pediatric Hepatobiliary Diseases and Treatments
  • Esophageal Cancer Research and Treatment
  • Gastrointestinal Tumor Research and Treatment
  • Gastroesophageal reflux and treatments
  • Liver Disease and Transplantation
  • Eosinophilic Esophagitis
  • Tracheal and airway disorders
  • Metastasis and carcinoma case studies
  • Biliary and Gastrointestinal Fistulas
  • Cancer-related Molecular Pathways
  • Pancreatitis Pathology and Treatment
  • Neuroendocrine Tumor Research Advances
  • Gastrointestinal disorders and treatments
  • Viral gastroenteritis research and epidemiology
  • Dysphagia Assessment and Management
  • Colorectal Cancer Surgical Treatments
  • Aortic aneurysm repair treatments
  • Genetic factors in colorectal cancer
  • Nitric Oxide and Endothelin Effects

Ospedale San Paolo
2023-2024

University of Milan
2024

Ospedali Riuniti Marche Nord
2016-2024

Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo
2022-2024

Middlesex University
2018

San Salvatore Hospital
2011-2012

University of Naples Federico II
2001-2008

University of Campania "Luigi Vanvitelli"
2001-2004

Policlinico S.Orsola-Malpighi
1998-2001

University of Bologna
1999-2001

See editorial on page 36. Up to 20% of health care personnel (HCP) were found be infected with coronavirus disease (COVID-19)1Lancet. 2020; 395: 922Abstract Full Text PDF Scopus (853) Google Scholar in the outbreak northern Italy.2Dipartimento della Protezione Civile.http://www.protezionecivile.gov.it/media-comunicazione/comunicati-stampaGoogle Recommendations patient and HCP protection have been made, such as postponing procedures, triage, use personal protective equipment (PPE), creation...

10.1053/j.gastro.2020.04.003 article EN other-oa Gastroenterology 2020-04-10

Endoscopic retrograde cholangiopancreatography (ERCP) represents the gold standard for jaundice palliation in patients with distal malignant biliary obstruction (DMBO). Biliary drainage using electrocautery lumen apposing metal stent (EC-LAMS) is currently a well-established procedure when ERCP fails. In palliative setting endoscopic ultrasound-guided gallbladder (EUS-GBD) could represent an easy and valid option. We performed prospective study new EC-LAMS primary aim to assess clinical...

10.1111/den.14606 article EN Digestive Endoscopy 2023-05-30

Abstract Background and study aims The optimal number of needle passes during endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) is not yet established. We aimed to perform a per-pass analysis the diagnostic accuracy EUS-FNB solid pancreatic lesions using 22G Franseen needle. Patients methods Consecutive patients with referred 11 Italian centers were prospectively enrolled. Three performed; specimens collected after each pass processed individually as standard histology following...

10.1055/a-2236-7654 article EN cc-by-nc-nd Endoscopy International Open 2024-01-02

Abstract Background and study aims The standard method for obtaining samples during endoscopic ultrasonography (EUS) is fine-needle aspiration (FNA), the accuracy of which can be affected by presence a cytopathologist in endoscopy room (rapid on-site evaluation [ROSE]). With introduction biopsy (FNB), macroscopic (MOSE) acquired specimen has been proposed. Only few studies have evaluated role MOSE all except one, 19G needle was used. Our primary aim to evaluate diagnostic yield with...

10.1055/a-1395-7129 article EN cc-by-nc-nd Endoscopy International Open 2021-05-27

This paper presents the development of a Robot Operating System (ROS)-based mobile robot control using electromyography (EMG) signals. The proposed robot’s structure is specifically designed to provide modularity and controlled by Raspberry Pi 3 running on top an ROS application Teensy microcontroller. EMG muscle commands are sent with hand gestures that captured Thalmic Myo Armband recognized k-Nearest Neighbour (k-NN) classifier. performance evaluated navigating it through specific paths...

10.3390/robotics7030036 article EN cc-by Robotics 2018-07-05

Background: Anastomotic leakages are one of the most frequent complications gastroesophageal surgery with a high mortality. Objective: This study aimed to assess efficacy and safety endoscopic therapy using fully covered self-expanding metal stents (FC-SEMS) for management anastomotic leaks. Methods: In this cohort study, all patients leak after oncological treated FC-SEMS were included. Procedures performed by expert endoscopist in three Italian units. The primary outcome was clinical...

10.2174/0115748871324401250114101416 article EN Reviews on Recent Clinical Trials 2025-01-31

Long and sharp objects can be foreign body intentionally or accidentally ingested. Timing of endoscopy relies on shape size, localization in gastrointestinal tract, patient's clinical conditions, occurrence symptoms, onset complications. We present a case 47-year-old male with no known comorbidity, who swallowed portion naso-pharyngeal swab half-broken during the second diagnostic test for SARS-CoV-2. The intact had total length 15 cm was made wood. patient asymptomatic, laboratory tests...

10.1007/s12328-020-01236-y article EN other-oa Clinical Journal of Gastroenterology 2020-09-20

Aims: Lumen-apposing metal stents (LAMSs) in ultrasonography-guided gallbladder drainage (EUS-GBD) have become increasingly important for high-risk surgical patients. Our study aims to evaluate the technical and clinical success, safety, feasibility of endoscopic using a new dedicated LAMS. Methods: This is retrospective multicenter that included all consecutive patients not suitable surgery who were referred tertiary center EUS-GBD electrocautery LAMS acute cholecystitis at eight different...

10.3390/diagnostics13213341 article EN cc-by Diagnostics 2023-10-30

Thyroid hormone receptors (TRs) and members of the myocyte enhancer factor 2 (MEF2) family are involved in regulation muscle-specific gene expression during myogenesis. Physical interaction between these two factors is required to synergistically activate transcription. p300/cAMP-response-element-binding-protein ('CREB')-binding protein (CBP) interacting with transcription able increase their activity on target promoters. We investigated role p300 regulating TR—MEF2A complex. To this end, we...

10.1042/bj20020057 article EN Biochemical Journal 2003-02-01

Cyclin D1 is a key cell-cycle regulatory protein required for the cell to progress through G1 S phase. We have shown by Western blot analysis that cyclin has wide distribution in adult mouse tissues, with its level of expression being tissue-dependent. Immunohistochemistry also may be present cytoplasm, nucleus or both these compartments: cytoplasmic staining was observed proliferating cells (e.g. kidney, intestine, stomach and salivary gland) non-dividing (the mature neurons brain), while...

10.1111/j.0021-8782.2004.00347.x article EN Journal of Anatomy 2004-11-01

The human HtrA family of proteases consists four members: HtrA1, HtrA2, HtrA3, and HtrA4. In humans the homologues appear to be involved in several important functions such as cell growth, apoptosis, inflammatory reactions, they control fate via regulated protein metabolism. previous studies it was shown that expression HtrA1 ubiquitous normal adult tissues. Here we examined its corresponding mRNA during mouse embryogenesis using Northern blotting hybridization, RT-PCR, immunohistochemical...

10.1369/jhc.4a6330.2004 article EN Journal of Histochemistry & Cytochemistry 2004-11-19

Summry— Signaling through the Notch cell surface receptors is a highly conserved mechanism of fate specification. signaling regulates proliferation, differentiation and death. In vertebrates, putative gene duplication has originated four genes, Notch‐1, −2, −3 −4. They have been implicated in neurogenesis, hematopoiesis, T‐cell development, vasculogenesis brain cortical growth. We investigated Notch‐1 distribution normal human tissues by immunohistochemistry immunoblot. detected widespread...

10.1111/j.1768-322x.2004.tb01418.x article EN Biology of the Cell 2004-05-01
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