A retrospective cohort design was used with the objective to evaluate cancer risk among people type 2 diabetes mellitus (T2DM) in Lithuania. The established by identifying all patients first diagnosis of T2DM National Health Insurance Fund database during 2000–2012. Cancer cases were identified record linkage Lithuanian Registry. Standardized incidence ratios (SIRs) calculated. Of 127,290 that included, 5959 men and 6661 women observed. statistically significant increase for sites observed...

Objective: We aimed to estimate survival in gastric cancer patients with type 2 diabetes mellitus (T2DM) using different antihyperglycemic medication.Methods: Patients and between 2003-2013 were identified form The Lithuanian Cancer Registry National Health Insurance Fund database.Cohort members classified into five groups: four groups of T2DM according treatment: metformin users; other medication sulphonylurea insulin non-diabetic group.Kaplan-Meier analysis Cox proportional hazards models...

We assessed gastric cancer risk in type 2 diabetes mellitus patients. Gastric patients with between 2001-2012 were identified. Four groups analysed: combination therapy metformin users; insulin and other medication sulfonylurea users. Standardised incidence ratios (SIRs) for cancers as a ratio of the observed number cases people to expected underlying general population calculated. A total 99,992 analysed 337 when compared 400.54 cases, according rates (SIR 0.84, 95% confidence interval...

This retrospective cohort study aimed to analyze overall and cause-specific mortality risk in people with type 2 diabetes mellitus (T2DM) Lithuania. Information on the diagnosis of T2DM glucose-lowering medication was obtained from National Health Insurance Fund database, causes death–from death certificates. Sex, age, calendar period-standardized ratios (SMRs) were calculated. In addition, 89,512 patients followed-up between 2010 2017, contributing observation period 592,321 person-years....

The aim of this study was to examine the association between type 2 diabetes (T2DM), use glucose-lowering medications and endometrial cancer (EC) risk. risk EC incidence among women with T2DM in Lithuania assessed using a retrospective cohort design. Female patients who were registered 1 January 2000 31 December 2012 identified National Health Insurance Fund database. cases (ICD-10 code C54) from Lithuanian Cancer Registry. Standardized ratios (SIRs) calculated by dividing observed numbers...

We aimed to estimate colorectal cancer risk in patients with type 2 diabetes mellitus (T2DM) using metformin. Patients and from 2000 2012 were identified form Lithuanian Cancer Registry the National Health Insurance Fund database. Standardized incidence ratios (SIRs) for cancers as a ratio of observed number cases people expected underlying general population was calculated. analysed 111 109 diabetes. Overall, 1213 versus 954.91 within period observation entailing an SIR 1.27 [95% confidence...

During the past decade, a huge interest was devoted to type-2 diabetes mellitus and their associations with prostate cancer development.The aim of this study determine whether type 2 treatment metformin is associated risk.The cohort composed diabetic male patients identified in National Health Insurance Fund database during 2000-2016 cases national Cancer Registry. We calculated standardized incidence ratios (SIR) for cancers as ratio observed number case people diagnosis expected underlying...

Background: We assessed the association between use of metformin and other antihyperglycemic medications on overall survival in diabetic patients with pancreatic cancer. Methods: Patients cancer diabetes 2000 2015 were identified from Lithuanian Cancer Registry National Health Insurance Fund database. Cohort members classified into six groups according to type 2 mellitus treatment: sulfonylurea monotherapy; insulin combination; medications; all combinations oral medications. Survival was...

Diabetes is associated with increased risk of various cancers but its association kidney cancer unclear. The objective this study was to evaluate the between T2DM or without metformin use and in a population-based national cohort Lithuania.The composed diabetic patients identified NHIF database during 2000-2012. Cancer cases were by record linkage Registry. Standardized incidence ratios (SIRs) for as ratio observed number expected underlying general population calculated.T2DM (11,592) 2000...

Abstract Purpose The aim of our study was to assess overall survival and cancer-specific in endometrial cancer patients with type 2 diabetes mellitus (T2DM) using metformin. Methods Patients T2DM during 2000–2012 period were identified from the Lithuanian Cancer Registry National Health Insurance Fund database. Cancer-specific primary outcomes. Results In we included 6287 women out whom 664 diagnosed (598 metformin users 66 never users). During follow-up (mean time 8.97 years), no...

We evaluated the effect of antihyperglycemic therapy on survival patients with lung cancer (LC). The analysis included LC and concomitant type 2 diabetes. 15,929 were classified into five groups: metformin users, insulin sulphonylurea users non-diabetic group. A multivariate showed that exposure to either or was associated a lower risk LC-specific mortality, this approached statistical significance (HR 0.82, 95% CI 0.72-92 for HR 0.65, 0.44-95 insulin). When deaths from all causes...

To assess prostate cancer-specific and overall survival in cancer patients with or without preexisting type 2 diabetes mellitus (T2DM) regards to metformin use.Patients diagnosed the Lithuanian population between 2001 2005 were identified through Cancer Registry followed until 2016, date of death, loss follow-up whichever came first. Information regarding diagnosis T2DM antihyperglycemic medications obtained from National Health Insurance Fund database. Prostate outcomes analysed using...

: This study aimed to evaluate the potential chemopreventive effect of antidiabetic medications, specifically metformin and pioglitazone, on lung cancer in patients with type 2 diabetes mellitus (T2DM). Additionally, dose-response relationship for use was analyzed.

The objective of our study was to evaluate bladder cancer risk among Lithuanian type 2 diabetes mellitus (T2DM) patients and the effect antihyperglycemic therapy on risk.

The aim of this study was to determine the association between insulin glargine usage and potential increase in cancer risk among Lithuanian population diagnosed with type 2 diabetes mellitus (T2DM).

130 Background: An inverse association has been shown between diabetes and prostate cancer risk. The aim of this study was to determine whether type 2 mellitus (T2DM) metformin is associated with Methods: A retrospective cohort design used examine the relationship composed male patients identified diagnosis T2DM in National Health Insurance Fund database during 2000–2016. Cancer cases were by record linkage Lithuanian Registry which a nationwide population-based registry that contains...

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

Abstract Background: The aim of this study was to determine whether type 2 diabetes mellitus and treatment with metformin is associated prostate cancer risk. Methods: Male patients diagnosis during the period 2000 – 2016 were identified in National Health Insurance Fund database. cases by pooling these records from national Cancer Registry. calculation stardardized incidence ratios (SIRs) composed as a ratio observed number case people expected underlying general population. Results:...