A5077953770- Platelet Disorders and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Peripheral Artery Disease Management
- Hemophilia Treatment and Research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Blood groups and transfusion
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Autoimmune Bullous Skin Diseases
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Ectopic Pregnancy Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Influenza Virus Research Studies
- Maternal and fetal healthcare
- Vaccine Coverage and Hesitancy
- Vascular Malformations and Hemangiomas
- Cardiac tumors and thrombi
Radboud University Medical Center
2018-2025
Radboud University Nijmegen
2018-2025
Geneeskundige en Gezondheidsdienst
2021
Limited data exists on persons with rare bleeding disorders (RBDs) possessing a heterozygous genotype, as most studies focus bi-allelic genotypes and more severe coagulation factor deficiencies. A growing body of evidence suggests that genotype experience clinically relevant symptoms. Explore the incidence symptoms postoperative in genotype. This cross-sectional sub-study Rare Bleeding Disorders Netherlands study (2017-2019) included deficiencies fibrinolysis or Clinical laboratory samples...
Patients with type 1 and 2 von Willebrand disease (VWD) can be treated desmopressin. Although a previous study has shown that the location of causative VWF gene variant is associated desmopressin response in VWD, association between variants not yet fully understood. Our primary aim was to compare VWD patients without variant. Secondly, we investigated whether depends on specific VWD. We included 250 from Netherlands study: 72 variant, 108 45 2A, 16 2M, 9 2N patients. analyzed ion...
Heavy menstrual bleeding (HMB) is associated with a reduced quality of life and limitations in social physical functioning. Data on HMB women rare disorders (RBDs), including coagulation factor deficiencies fibrinolytic disorders, are scarce.To analyze the prevalence, severity, treatment Dutch an RBD.The Rare Bleeding Disorders Netherlands (RBiN) study included 263 patients RBD from all 6 hemophilia centers (October 2017-November 2019). In this analysis, data 111 aged ≥16 years were studied....
We present a rare case of acquired von Willebrand syndrome (AVWS) caused by mantle cell lymphoma. A 61-year-old male suffered from recurrent bleeding symptoms since few months. Initially, physical examination was normal. factor antigen (VWF:Ag) level and VIII activity (FVIII:C) were low (0.31 IU/ml 0.43 IU/ml, resp.). Ristocetin cofactor (VWF:RCo) 0.09 collagen binding (VWF:CB) 0.10 IU/ml. VWF:RCo/VWF:Ag ratio 0.29, RIPA value Highest molecular weight VWF multimers absent. diagnosis Disease...