Michael Bernhard

ORCID: 0000-0003-1179-7943
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About
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Research Areas
  • Monoclonal and Polyclonal Antibodies Research
  • Immunotherapy and Immune Responses
  • Airway Management and Intubation Techniques
  • COVID-19 diagnosis using AI
  • Cardiac Arrest and Resuscitation
  • Radiopharmaceutical Chemistry and Applications
  • Artificial Intelligence in Healthcare and Education
  • Respiratory Support and Mechanisms
  • Effects of Radiation Exposure
  • Radiation Dose and Imaging
  • Virus-based gene therapy research
  • Macrophage Migration Inhibitory Factor
  • PARP inhibition in cancer therapy
  • Orthopaedic implants and arthroplasty
  • Myofascial pain diagnosis and treatment
  • Hepatitis B Virus Studies
  • Cytomegalovirus and herpesvirus research
  • Biliary and Gastrointestinal Fistulas
  • Nanoparticle-Based Drug Delivery
  • Lymphoma Diagnosis and Treatment
  • Tracheal and airway disorders
  • Trauma and Emergency Care Studies
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac Health and Mental Health
  • Advanced Biosensing Techniques and Applications

Düsseldorf University Hospital
2023-2025

Heinrich Heine University Düsseldorf
2023-2025

University Hospital Leipzig
2013

Klinikum Fulda
2011

University Medical Center Hamburg-Eppendorf
2008

Universität Hamburg
2008

University of Münster
1997

Goethe University Frankfurt
1997

University of Virginia Medical Center
1983

Kettering University
1972-1973

Background Large language models (LLMs) have demonstrated impressive performances in various medical domains, prompting an exploration of their potential utility within the high-demand setting emergency department (ED) triage. This study evaluated triage proficiency different LLMs and ChatGPT, LLM-based chatbot, compared to professionally trained ED staff untrained personnel. We further explored whether LLM responses could guide effective Objective aimed assess efficacy associated product...

10.2196/53297 article EN cc-by Journal of Medical Internet Research 2024-06-14

Abstract Background Alcohol intoxication is known to affect blood coagulation. The specific effects remain poorly understood. Here, we investigate the impact of severe alcohol on clotting by comprehensive coagulation testing. Methods A prospective study included 21 patients admitted emergency department University Hospital Düsseldorf with (target concentration > 2 g/l). Platelet function and was compared between states soberness using multiple platelet analysis, thrombelastography...

10.1007/s00414-025-03449-7 article EN cc-by International Journal of Legal Medicine 2025-02-22

Abstract Sera from many patients with tumors showed demonstrable cytotoxic antibody activity against selected human tumor cells in culture. The detected the present study was not found to be specific for tumors, but shown directed an antigen that is serologically related blood group A. Direct cytotoxicity and absorption analyses, blocking tests, erythrocyte adherence tests confirmed this conclusion. Antibody found, as expected, frequently sera blood‐groups O B phenotypes, belonging A or AB....

10.1002/ijc.2910120103 article EN International Journal of Cancer 1973-07-15

Indirect immunofluorescence studies with sera from breast cancer patients were conducted on cell lines derived human cancers. A new antigen was demonstrated in 2 primary cultures of 11 and established carcinoma studied. Eighty-five percent cells per field an intense granular cytoplasmic fluorescence. Thirty-five additional normal tumors non origin including 7 sarcoma negative where tested positive sera. Ninety-one (22/24) free metastatic disease obta ined 7–10 days after surgery for...

10.1093/jnci/48.4.1137 article EN JNCI Journal of the National Cancer Institute 1972-04-01

In literature data, an uncertainty exists whether occurrence of bilateral breast cancer decreases the survival probability affected patients. Therefore, we analyzed medical records 498 postoperatively irradiated (1977-1982) female patients (T1-4,N0-3,M0). follow-up time, in 36 a carcinoma treated by surgery with or without radiotherapy was found. The 10-year overall rates were 54% who had unilateral disease, compared 56% patients, respectively. incidence metastasis did not differ between...

10.1097/00000421-199712000-00001 article EN American Journal of Clinical Oncology 1997-12-01

General immunobiologic studies in cancer patients have stressed measurements of lymphocyte function and commonly ignored the monocyte-macrophage system. A preliminary study peripheral blood was undertaken a group 90 (18 breast, 32 colon, 13 head neck, 9 lung, 18 melanoma) 70 controls. Studies included enumeration extractible monocytes (EM), quantitation differentiation into macrophages (macrophage precursor test: MP), evaluation antibody-dependent cellular cytotoxicity (ADCC), spontaneous...

10.1002/1097-0142(19830215)51:4<669::aid-cncr2820510420>3.0.co;2-1 article EN Cancer 1983-02-15

The blastogenic responsiveness of peripheral blood lymphocytes is a commonly applied measure immune response capability. This assay generally run under conditions maximum lymphocyte stimulation. purpose this study was to evaluate which culture were able best discriminate normal from subnormal responses mitogens and antigens. Mitogen or antigen concentrations the length incubation time varied while other (serum supplement, concentration, amount label, label pulse) kept constant. A total 24...

10.4049/jimmunol.124.2.964 article EN The Journal of Immunology 1980-02-01

Die notfallmedizinische Versorgung von Opfern eines Sexualdelikts ist eine besondere Herausforderung: In einer aus Patientensicht bestehenden psychischen Ausnahmesituation müssen nicht nur Verletzungen versorgt, sondern auch gerichtsfeste Befunddokumentation und sachgerechte Spurensicherung gewährleistet werden.

10.1055/s-0034-1396221 article DE Geburtshilfe und Frauenheilkunde 2015-04-14

Zusammenhang Im Einsatzspektrum des professionellen Rettungsdienstes stellen Atemwegsnotfälle („A-Probleme“) einen seltenen, respiratorische Notfälle („B-Probleme“) hingegen häufigen Einsatzgrund dar. Die Vorhaltung entsprechenden Materials, Schulung und regelmäßiges Training, die Etablierung von SOPs gelebtes Teamwork sind wesentliche Aspekte für ein erfolgreiches Atemwegsmanagement, das S1-Leitlinie „Prähospitales Atemwegsmanagement“ praktischen Leitfaden bietet.

10.1055/a-1154-1959 article DE Notfallmedizin up2date 2020-12-01

Ziele: Die Multidetektor-Computertomographie (MDCT) hat einen zentralen Stellenwert in der Schockraumdiagnostik des Schwerverletzten, ist aber mit einer nicht unerheblichen Strahlenbelastung assoziiert. Ziel vorliegenden Untersuchung war es, diese durch den Einsatz verschiedener Lagerungshilfen und unterschiedlichen Lagerungstechniken zu reduzieren. Methode: In retrospektiven wurde die einem 16-Zeilen-MDCT assoziierte Strahlendosis [DLP (mGy*cm)] Thorax-Abdomenscans (geräteseitige Angaben im...

10.1055/s-0031-1279135 article DE RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 2011-04-01

Ziele: Das moderne Traumamanagement polytraumatisierter Patienten beinhaltet die initiale Immobilisierung der am Unfallort auf geeigneten Immobilisationshilfen. Bislang gibt es keine verlässlichen Daten bzw. Herstellerangaben bzgl. des Einflusses dieser Lagerungsmittel Strahlenbelastung Bildqualität im Rahmen Ganzkörper-CT-Diagnostik (Traumascan). Wir untersuchten den Einfluss neun unterschiedlicher Immobilisationshilfen o.g. Kriterien. Methode: Es wurde Lagerungs- und Transportmittel eines...

10.1055/s-0033-1346445 article DE RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren 2013-04-26

<sec> <title>BACKGROUND</title> Large language models (LLMs) have demonstrated impressive performances in various medical domains, prompting an exploration of their potential utility within the high-demand setting emergency department (ED) triage. This study evaluated triage proficiency different LLMs and ChatGPT, LLM-based chatbot, compared to professionally trained ED staff untrained personnel. We further explored whether LLM responses could guide effective </sec> <title>OBJECTIVE</title>...

10.2196/preprints.53297 preprint EN 2023-10-02
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