A5038182422- Multiple Sclerosis Research Studies
- Autoimmune and Inflammatory Disorders Research
- Artificial Intelligence in Healthcare and Education
- SARS-CoV-2 and COVID-19 Research
- Peripheral Neuropathies and Disorders
- COVID-19 diagnosis using AI
- Parkinson's Disease Mechanisms and Treatments
- Machine Learning in Healthcare
- Topic Modeling
- Psoriasis: Treatment and Pathogenesis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Stroke Rehabilitation and Recovery
- Genomics and Rare Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological diseases and metabolism
- Dermatology and Skin Diseases
- Fungal Infections and Studies
- Botulinum Toxin and Related Neurological Disorders
- Neurological disorders and treatments
- RNA regulation and disease
- Clinical practice guidelines implementation
- Neonatal Respiratory Health Research
- Hereditary Neurological Disorders
- Neonatal and Maternal Infections
- Acute Ischemic Stroke Management
Heinrich Heine University Düsseldorf
2022-2025
Düsseldorf University Hospital
2022-2025
University Hospital Münster
2020
Background Large language models (LLMs) have demonstrated impressive performances in various medical domains, prompting an exploration of their potential utility within the high-demand setting emergency department (ED) triage. This study evaluated triage proficiency different LLMs and ChatGPT, LLM-based chatbot, compared to professionally trained ED staff untrained personnel. We further explored whether LLM responses could guide effective Objective aimed assess efficacy associated product...
Background Vaccination has proven to be effective in preventing SARS-CoV-2 transmission and severe disease courses. However, immunocompromised patients have not been included clinical trials real-world data point an attenuated immune response vaccines among with multiple sclerosis (MS) receiving immunomodulatory therapies. Methods We performed a retrospective study including 59 ocrelizumab (OCR)-treated MS who received vaccination. Anti-SARS-CoV-2-antibody titres, routine blood parameters...
The evidence-based acute treatment of stroke patients in Germany is carried out according to standardized algorithms more than 300 certified units, and its quality repeatedly assured by the German Stroke Society (DSG) others. However, nationally structured uniform aftercare programs are missing, despite evidence that they contribute success rehabilitation improvement everyday life. We used a 27-item online questionnaire, which was mailed 4,195 outpatient physicians catchment area...
The RELY-CD study investigated the long-term clinical response to botulinum neurotoxin type A in cervical dystonia within a multicenter, real-world setting. This retrospective focused on patients treated with complex-free (incobotulinumtoxinA) and complex-containing (onabotulinumtoxinA abobotulinumtoxinA) BoNT/A formulations over an up 10-year period. novel dose–effect parameter “DEff” was introduced quantify relationship between dose adjustments outcomes, enabling identification of partial...
Therapeutic options targeting inflammation in multiple sclerosis (MS) have evolved rapidly for relapsing-remitting MS, whereas few therapies are available progressive forms of particular secondary MS (SPMS). The approval siponimod SPMS has allowed optimism the otherwise discouraging therapeutic landscape.We conducted a retrospective, multicenter, non-interventional study analyzing efficacy and safety under real-world conditions 227 patients. According to retrospective framework, data was...
Introduction Given the varying severity of coronavirus disease 2019 (COVID-19) and rapid spread Severe-Acute-Respiratory-Syndrome-Corona-Virus-2 (SARS-CoV-2), vaccine-mediated protection particularly vulnerable individuals has gained increasing attention during course pandemic. Methods We performed a 1-year follow-up study 51 ocrelizumab-treated patients with multiple sclerosis (OCR-pwMS) who received COVID-19 vaccination in 2021. retrospectively identified 37 additional OCR-pwMS, 42 pwMS...
Abstract Although substantial progress has been achieved concerning neonatal sepsis, its lethality remains considerably high, and further insights into peculiarities malfunctions of immunity are needed. This study aims to contribute a better understanding the role human granulocyte subpopulations calgranulin C (S100A12). For this purpose, we gathered 136 cord blood (CB) samples. CD66b+ CB low-density granulocytes (LDG) normal-density were isolated functionally phenotypically compared with...
<sec> <title>BACKGROUND</title> Large language models (LLMs) have demonstrated impressive performances in various medical domains, prompting an exploration of their potential utility within the high-demand setting emergency department (ED) triage. This study evaluated triage proficiency different LLMs and ChatGPT, LLM-based chatbot, compared to professionally trained ED staff untrained personnel. We further explored whether LLM responses could guide effective </sec> <title>OBJECTIVE</title>...