- Pediatric Pain Management Techniques
- Anesthesia and Pain Management
- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Nausea and vomiting management
- Intensive Care Unit Cognitive Disorders
- Enhanced Recovery After Surgery
- Gastroesophageal reflux and treatments
- Pain Management and Placebo Effect
- Spine and Intervertebral Disc Pathology
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Opioid Use
- Cardiovascular Syncope and Autonomic Disorders
- Thermal Regulation in Medicine
- Sleep and Wakefulness Research
- Cancer survivorship and care
- Migraine and Headache Studies
- Hernia repair and management
- Congenital Diaphragmatic Hernia Studies
- Venous Thromboembolism Diagnosis and Management
- Cancer, Stress, Anesthesia, and Immune Response
- Airway Management and Intubation Techniques
- Pain Mechanisms and Treatments
- Clinical Laboratory Practices and Quality Control
- Intestinal and Peritoneal Adhesions
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2015-2024
University of Milan
2024
Società Italiana di Reumatologia
2024
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2014-2023
University of Milano-Bicocca
2010-2023
Montreal Children's Hospital
2019-2022
McGill University
2019
Azienda Ospedaliera San Gerardo
2010-2016
Ospedale Maggiore
2007-2016
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2015
Summary Background Early negative postoperative behavior (e‐ PONB ) is common in children and manifests itself as emergence agitation ( EA ), delirium ED pain. The objective of this prospective double blind, randomized, placebo‐controlled trial was to determine whether IV clonidine or fentanyl prior surgery modifies e‐ children. Methods Ninety scheduled for subumbilical under sevoflurane anesthesia supplemented with regional were randomized either receive 2 mcg·kg −1 , placebo saline) before...
Summary Background Children commonly display early postoperative negative behavior (e‐ PONB ) after general anesthesia, which includes emergence delirium ( ED ), discomfort, temperament, and pain. However, it is often difficult for the caregiver to discriminate between various aspects of e‐ . Objective This prospective observational study evaluates possibility distinguish pain in young children using validated pediatric scales phase. Methods Following institutional approval written consent,...
In Brief BACKGROUND: Studies evaluating intraperitoneal local anesthetic instillation for pain relief after laparoscopic procedures have reported conflicting results. this randomized, double-blind study we assessed the effects of nebulization on cholecystectomy. METHODS: Patients undergoing elective cholecystectomy were randomly assigned to receive either ropivacaine 0.5%, 20 mL induction pneumoperitoneum, or 1%, 3 before and surgery. Anesthetic surgical techniques standardized. Degree at...
Summary Background There is very few information regarding pain after craniotomy in children. Objectives This multicentre observational study assessed the incidence of major Methods After IRB approval, 213 infants and children who were <10 years old undergoing consecutively enrolled nine Italian hospitals. Pain intensity, analgesic therapy, adverse effects evaluated on first 2 days surgery. Moderate to severe was defined as a median FLACC or NRS score ≥4 points. Severe ≥7 Results Data 206...
Background and objective Xenon anaesthesia may have the potential to reduce postoperative cognitive impairment after general anaesthesia. This randomized double-blind controlled trial was designed compare early recovery xenon sevoflurane Methods After institutional ethics approval, we obtained informed written consent from 60 adults, with American Society of Anesthesiologists I or II status, scheduled for elective surgery an estimated time between 360 min. Patients were receive Both groups...
Background: Although Moral Distress (MD) is a matter of concern within the Pediatric Intensive Care Unit (PICU), there no validated Italian instrument for measuring phenomenon in nurses and physicians who care pediatric patients Care. The authors Scale-Revised (Italian MDS-R), adult setting, 2017, invited further research to evaluate generalizability scale clinicians working other fields. Our study aims reduce this knowledge gap by developing validating version MDS-R. Methods: We evaluated...
Unsettled behaviors characterize the early phase after general anaesthesia in pediatric population up to 80% of cases. Emergence delirium (ED) and acute pain are two most relevant sources this phenomenon. Research clinical guidelines difficult implement due variability definition unsettled behavior measurement different components. The probable incidence ED is between 10% 20%, potential risk factors could be summarized as young age, male gender, preoperative anxiety, baseline...
Background . Intraperitoneal nebulization of ropivacaine reduces postoperative pain and morphine consumption after laparoscopic surgery. The aim this multicenter double-blind randomized controlled trial was to assess the efficacy different doses dose-related absorption when nebulized in peritoneal cavity during cholecystectomy. Methods Patients were receive 50, 100, or 150 mg 1% by through a nebulizer. Morphine consumption, intensity abdomen, wound shoulder, time unassisted ambulation,...
The evidence supporting the use of pharmacological treatments in pediatric chronic pain is limited. Quantitative sensory testing (QST) and conditioned modulation evaluation (CPM) provide information on phenotype, which may help clinicians to tailor treatment. This retrospective study aimed evaluate association between QST/CPM phenotyping selection treatment for children with conditions. We retrospectively analyzed medical records 208 female patients (mean age 15 ± 2 years) enrolled an...
In Brief BACKGROUND: Epidural infusion of levobupivacaine and ropivacaine provides adequate postoperative pain management by minimizing side effects related to IV opioids improving patient outcome. The safety profile different drugs can be better estimated comparing their pharmacokinetic profiles than considering objective effects. Because have properties, our aim was investigate whether there is a difference in the variability 2 homogeneous population undergoing continuous epidural...
The immune system of children with acute lymphoblastic leukemia (ALL) is affected by both the underlying disease and chemotherapy. Children ALL receive sedation for diagnostic therapeutic procedures, which may contribute to competence alteration. effects propofol-ketamine combination on have not been investigated. This cohort study was designed assess immunomodulatory activity proinflammatory anti-inflammatory cytokines undergoing painful procedures. We enrolled 20 bone marrow aspiration...
Chronic headaches are a major source of morbidity in the pediatric population, affecting physical function, school attendance, social capacity, mood, and sleep. In adults, repetitive sphenopalatine ganglion (SPG) blockade has been studied as preventive treatment for chronic migraines. This case series aims to evaluate SPG block daily headache (CDH) adolescents. We prospectively evaluated 17 adolescents (14 females, 14 ± 1 year) with CDH not responding cognitive behavioral therapy (CBT),...
Transfer critically ill newborn to the operating theater is a very difficult challenge for nurses, anesthesiologists, neonatologists and surgeons. Most of these patients are mechanically ventilated cardiocirculatory supported. The biggest premature infants that need leave incubator, while outside Neonatal Intensive Care Unit (NICU), maintaining temperature homeostasis. A male preterm newborn, born at 28 gestational week with birth weight 700 g underwent major surgical procedure due type C...
1Royal Aberdeen Children's Hospital, Dept of Anaesthesiology, Aberdeen, United Kingdom, 2San Gerardo University Monza, Italy
Ingelmo, P. M.; Bucciero, Somaini, Sahillioğlu, E.; Garbagnati, A.; Charton, Rossini, V.; Sacchi, Scardelli, Lometti, Joshi, G. P.; Fumagalli, R.; Diemunsch, Author Information