A5054171879- Bone health and treatments
- Bone health and osteoporosis research
- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Bone Metabolism and Diseases
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Neuroendocrine Tumor Research Advances
- Atherosclerosis and Cardiovascular Diseases
- Estrogen and related hormone effects
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Coffee research and impacts
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Cardiac Imaging and Diagnostics
- Adipokines, Inflammation, and Metabolic Diseases
- Gastroesophageal reflux and treatments
- Muscle metabolism and nutrition
- Diet and metabolism studies
- Bone and Joint Diseases
- Medical Imaging Techniques and Applications
Aarhus University Hospital
2020-2024
Central Denmark Region
2024
Steno Diabetes Centers
2020-2024
Aarhus University
2019-2024
Arterial 18fluorodeoxyglucose (FDG) positron emission tomography (PET) is considered a measure of atherosclerotic plaque macrophages and used for quantification disease activity in clinical trials, but the distribution profile FDG across other arterial cells has not been fully clarified. The purpose this study was to analyze uptake different tissues their contribution PET signal normal arteries. Wild-type D374Y-PCSK9 transgenic Yucatan minipigs were fed high-fat, high-cholesterol diet induce...
Background Type 2 diabetes mellitus (T2D) is associated with an increased fracture risk. It debated whether sodium-glucose cotransporter (SGLT2) inhibitors influence risk in T2D. We aimed to investigate the of major osteoporotic fractures (MOF) SGLT2 compared glucagon-like peptide 1 (GLP-1) receptor agonists when used as add-on therapies metformin. Methods conducted a population-based cohort study using Danish national health registries. Diagnoses were obtained from discharge diagnosis codes...
Patients with diabetes mellitus have an increased risk of fractures; however, the underlying mechanism is largely unknown. We aimed to investigate whether major osteoporotic fractures in patients differs between subjects initiated alendronate and denosumab, respectively.
Type 2 diabetes mellitus (T2D) is associated with an increased fracture risk. There little evidence for the effects of glucagon-like peptide 1 receptor agonists (GLP-1RA) on risk in T2D. We aimed to investigate major osteoporotic fractures (MOF) treatment GLP-1RA compared dipeptidyl peptidase 4 inhibitors (DPP-4i) as add-on therapies metformin.We conducted a population-based cohort study using Danish national health registries. Diagnoses were obtained from discharge diagnosis codes (ICD-10...
Objective A link has been proposed between glucose homeostasis and bone metabolism. Bisphosphonates are first-line treatment of osteoporosis, we aimed to investigate whether the risk developing type 2 diabetes was associated with prior use alendronate. Research Design Methods We conducted a population-based nested case-control study through access all discharge diagnoses (ICD-10 system) from National Danish Patient Registry along redeemed drug prescriptions (ATC classification Health Service...
: Coffee consumption is inversely associated with type 2 diabetes. Cafestol, a bioactive compound in coffee, has demonstrated glucose-lowering and insulin-secretory properties cell animal studies. The acute effects of cafestol on glucose metabolism humans have only been briefly investigated, longer-term not explored. This study aimed to assess the purified insulin sensitivity other metabolic parameters healthy individuals increased waist circumference at risk developing
To investigate whether sodium-glucose cotransporter-2 (SGLT2) inhibitor use as compared to dipeptidyl peptidase-4 (DPP-4) add-on metformin is associated with the risk of any fracture or major osteoporotic fractures (MOFs).A cohort study using Clinical Practice Research Datalink (CPRD) Aurum database was conducted. All patients aged 18 years and older a first-ever prescription for DPP-4 an SGLT2 between January 1, 2013 June 30, 2020 were selected. Patients starting inhibitors matched (up 1:3)...
Type 2 diabetes mellitus (T2DM) and osteoporosis are two major public health concerns worldwide, contributing to morbidity mortality in the elderly. Aging is one of most significant risk factors for low bone mass, fragility, fractures. Among several comorbidities that affect elderly with diabetes, increased fracture a relatively recently discovered complication. Generally, individuals T2DM exhibit higher mineral density, which complicates assessment risk. Despite growing evidence an...
Abstract Purpose Osteoglycin is hypothesized to be metabolically active and may enhance insulin action. We that osteoglycin levels increase during hyperglycemia as a physiological response the effects of insulin. Methods Eight healthy males were included in cross-over study consisting three days following an 8 h fast. First, we performed oral glucose tolerance test (OGTT); second, isoglycemic intravenous infusion (IIGI); third, control period hour analyzed blood samples for circulating days....
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)