A5038997493- Muscle Physiology and Disorders
- Exercise and Physiological Responses
- Adipose Tissue and Metabolism
- Ion channel regulation and function
- Laser Applications in Dentistry and Medicine
- Muscle metabolism and nutrition
- Science and Education Research
- Advanced Sensor and Energy Harvesting Materials
- HIV/AIDS Research and Interventions
- Venomous Animal Envenomation and Studies
- Muscle activation and electromyography studies
- Youth, Drugs, and Violence
- Pain Mechanisms and Treatments
- Adolescent Sexual and Reproductive Health
- Mitochondrial Function and Pathology
- Physical Education and Gymnastics
- Chemistry Education and Research
- Hormonal and reproductive studies
- Mesenchymal stem cell research
- Physical Education and Sports Studies
- Leprosy Research and Treatment
- Trigeminal Neuralgia and Treatments
- Trypanosoma species research and implications
- Coenzyme Q10 studies and effects
- Ocular Oncology and Treatments
Universidade de Brasília
1980-2023
Universidade Estadual de Campinas (UNICAMP)
2001-2023
Institut Català d'Oncologia
2017
Institut d'Investigació Biomédica de Bellvitge
2017
Universidade Paulista
2011-2016
Universidade Federal do Rio de Janeiro
2009
Pontifícia Universidade Católica de Campinas
2005
Universidade Federal de São Carlos
1997-1998
A perda de sangue do sistema circulatório é, inicialmente, compensada fisiologicamente pelo organismo. Contudo, o prolongamento quadro hemorragia aguda pode levar ao choque hemorrágico grave, no qual comprometimento da função cardíaca associado a arritmias letais culminam em um desfecho fatal falência órgãos. O tratamento atual transfusão com hemoderivados naturais, como concentrado hemácias (PRBCs), plasma fresco congelado (FFP) e plaquetas, possui limitação depender diretamente...
A neuralgia trigeminal é uma das patologias de dor facial e está entre as mais incapacitantes que afetam a qualidade vida dos pacientes. Pode ser classificada como: primária, secundária, idiopática pós-traumática. O objetivo do presente estudo em revisar literatura existente quanto características clínicas, diagnóstico tratamento NT. Para isso, utilizou-se base dados PubMed os descritores Trigeminal Neuralgia, Diagnosis, Dentistry. Obtiveram-se 89 artigos quais 30 se encaixaram nos critérios...
Increased oxidative stress is a frequent feature in Duchenne muscular dystrophy (DMD). High reactive oxygen species (ROS) levels, associated with altered enzyme antioxidant activity, have been reported dystrophic patients and mdx mice, an experimental model of DMD. In this study, we investigated the effects coenzyme Q10 (CoQ10) on marker levels calcium concentration primary cultures muscle cells from mice. Primary skeletal C57BL/10 mice were treated (5 μM) for 24 h. The untreated used as...
The mdx mouse phenotype aggravated by chronic exercise on a treadmill makes this murine model more reliable for the study of muscular dystrophy. Thus, to better assess Tempol effect dystrophic pathways, analyses in were performed blood samples and diaphragm muscle from trained adult (7–11-weeks old) animals. m dx mice divided into three groups: mdxSed , sedentary controls ( n = 28); Ex, exercise-trained animals Ex+T, with treatment 28). results demonstrated that promoted strength gain,...
The aim of the present study was to evaluate effect leucine treatment (0.30 mM) on muscle weight and signaling myoproteins related synthesis degradation pathways soleus following seven days complete sciatic nerve lesion.Wistar rats (n=24) 3 4 months age (192 ± 23 g) were used. animals randomly distributed into four experimental groups (n=6/group): control, treated with (L), denervated (D) (DL).Dependent measures proteins levels AKT, AMPK, mTOR, ACC performed by Western blot. Leucine induced...
Abstract Oxidative stress is a critical element in relationship to the pathophysiology of Duchenne muscular dystrophy (DMD). In mice diaphragm (DIA) most resembles dystrophic human pathology. this study we have evaluated consequences synthetic antioxidant (tempol) on oxidative parameters DIA muscle mdx mice. The were separated into two groups: mdx, control group receiving intraperitoneal (i.p.) injections saline solution (100 µL), and mdxT, treated i.p. tempol mg/kg). tempol‐treated showed...
Background Ca2+ dysregulation and oxidative damage appear to have a central role in Duchenne muscular dystrophy (DMD) progression. The current study provides muscle cell-specific insights into the effect of Tempol on TRPC 1 channel; positive negative regulators cell differentiation; antioxidant enzymatic system; activators mitochondrial biogenesis; inflammatory process dystrophic primary cells culture.Mdx myotubes were treated with (5 mM) for 24 h. Untreated mdx C57BL/10 used as controls.The...
Abstract Dystrophic muscles show alterations in the dystrophin–glycoprotein complex and a lack of neuronal nitric oxide (NO) synthase. In mdx mice, presynaptic expression NO synthase is decreased, suggesting that signaling may be altered dystrophic muscle. this study, we examined nerve‐terminal Schwann‐cell responses after crush lesion control NO‐deficient mice. Seven days nerve crush, 24% neuromuscular junctions ( n = 200) showed ultraterminal sprouts, whereas mice frequency was 28.5% 217;...
The distribution of nitric oxide synthase at the neuromuscular junction (NMJ) normal, denervated and mdx mice was studied using a specific antibody against neuronal isoform (nNOS). Fluorescence confocal microscopy demonstrated that nNOS immunoreactivity localised mainly in sarcolemma presynaptic region covering acetylcholine receptor branches. expression greatly reduced dystrophin‐deficient muscles. In normal muscles, still present there were no qualitative changes this protein. These...
Objective: This study evaluated photobiomodulation therapy (PBMT) effects on the factors involved in mitochondrial biogenesis, respiratory complexes, and transient receptor potential canonical channels (such as TRPC-1 TRPC-6) vitro (mdx muscle cells) vivo studies (gastrocnemius muscle) from mdx mice, dystrophin-deficient model of Duchenne muscular dystrophy (DMD). Background: There is no successful treatment for DMD, therefore demanding search new therapies that can improve role, quality...
The purpose of this study is to investigate the association insulin resistance (IR) with dietary, fitness, anthropometric and other components metabolic syndrome (MS) in adult participants. Cross-sectional 80 participants (58±8 years old) were clinically ethically selected. They all assessed for anthropometry, dietary habits, plasma biochemistry indirect measurement maximal oxygen uptake (VO2max). Participants diagnosed MS by IDF criterion placed 3 different groups using tertiles of HOMA-IR....
Objetivo: Analisar a vulnerabilidade ao HIV de adolescentes e jovens estudantes do ensino médio escolas públicas. Método: Pesquisa descritiva, transversal, realizada em Ceilândia (Distrito Federal). Foram avaliados indivíduos ambos os sexos 11 públicas médio. Para ser incluídos, voluntários deveriam ter entre 15-24 anos estar matriculados na rede pública. excluídos que apresentavam problemas cognitivos impedissem entendimento instrumento. Utilizamos instrumento autoaplicável, com questões...
: O Lian Gong é uma modalidade terapêutica chinesa que consiste em um conjunto de exercícios, organizados séries, visando a prevenção dores no corpo, problemas osteomusculares e articulares, além atuar nas disfunções dos órgãos internos, respiratórios redução do estresse. meio virtual se mostrou útil para reestruturação ações extensão modo garantir continuidade das interação da universidade com sociedade. Projeto Extensão ‘’Lian Gong: Pílulas tranquilidade seu dia’’ também precisou...
The aim of this work is to analyze irrigation for food production in the municipal districts Petrolina, State Pernambuco (PE), Juazeiro, Bahia (BA), and Vale do Açu Ceará-Mirim, Rio Grande Norte (RN), all which are located semi-arid northeastern region Brazil.In Petrolina highest productivity rates achieved cultivating grapes mangos, considered principal fruits export market.The infrastructure irrigated perimeters includes availability water electric power supply both large small producers...
Objetivos: O objetivo do presente trabalho foi analisar a vulnerabilidade ao HIV de jovens estudantes universitarios. Metodos: Trata-se pesquisa descritiva tipo levantamento realizada com universitarios ambos os sexos (n=243), idade entre 15 24 anos (19,23±1,54). Aplicamos o questionario: “Eu preciso fazer teste HIV/AIDS?”, adicionando questoes sobre idade, sexo e relacao sexual mais frequente. Resultados: Na amostra, 73,2% eram feminino (n=177). A frequente heterossexual (66,7%), seguida...
Several side effects of anabolic-androgenic steroid (AAS) administration associated with training are reported in the biomechanical properties calcaneal tendon (CT) rats. Thus, aim present study is to evaluate detraining and discontinuation AAS on CT morphology rats submitted exercise water. Animals were divided into two groups (20/group): (1) Immediately after (IA), (2) Six weeks (6W). The IA group included four subgroups: Sedentary (S), Trained (T), (SAAS), trained (TAAS). 6W (6W-S), six...
O objetivo do presente estudo foi revisar a literatura sobre os aspectos histologicos das celulas satelites (CSs), seu papel na regeneracao de lesoes musculares mediadas e sinais que levam ativacao diferenciacao CSs em novos miocitos. As bases dados eletronicas PubMed, SciELO MedLine foram consultadas retroscpectivamente no periodo 1990 2014 usando as palavras-chave satelites, muscular, “satellite cells”, “muscle repair”, “injured muscular tissue” stem cells”. Com estrategia inicial...
Objetivos: Avaliar a disponibilidade de futuros fisioterapeutas em trabalhar voluntariamente no atendimento bombeiros durante grandes emergências e aceitação desses serviços por uma corporação. Métodos: Pesquisa descritiva exploratória levantamento realizada meio questionário aplicado graduandos fisioterapia (n = 47) 79). Resultados: Entre os foi observado que 70% trabalhariam apenas 4% não trabalharia. O restante respondeu talvez trabalhasse se houvesse remuneração ou pudessem estipular...
Os objetivos deste trabalho foram identificar os índices de detecção e prevalência da hanseníase em Bragança Paulista - SP, no período 1999 a 2006, delineando o predomínio forma doença comparar graus incapacidades notificados diagnóstico na alta do tratamento. As informações coletadas prontuários, fichas notificação SINAN DATASUS (n=171). Foram realizadas análises qualitativas quantitativas usando teste Qui-quadrado (p≤0,01). analisados 171 prontuários nestes, foi observado que apenas 47%...