A5032110613- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Cardiac Structural Anomalies and Repair
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Imaging and Diagnostics
- Infectious Aortic and Vascular Conditions
- Cardiac Arrest and Resuscitation
- Pulmonary Hypertension Research and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac and Coronary Surgery Techniques
- Cardiac Arrhythmias and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Hospital Admissions and Outcomes
- Congenital Heart Disease Studies
- Cardiovascular Function and Risk Factors
- Surgical Simulation and Training
- Innovations in Medical Education
- Orthopedic Surgery and Rehabilitation
- IL-33, ST2, and ILC Pathways
- Neurosurgical Procedures and Complications
Duke-NUS Medical School
2024-2025
National Heart Centre Singapore
2014-2024
Singapore General Hospital
2014-2024
Changi General Hospital
2023
E Ink (South Korea)
2019
National University of Singapore
2001-2017
The University of Melbourne
2006
St Vincent's Hospital
2006
Tan Tock Seng Hospital
2001
To review our experience of surgical management infective endocarditis (IE) over a 13-year period and analyse the outcomes associated prognostic factors.A retrospective was conducted for 191 consecutive patients who underwent surgery native prosthetic valve (PVE) between January 2000 December 2012. Surgical were reviewed to include survival postoperative complications. Follow-up complete 172 179 (96.1%) surviving hospital discharge, with mean follow-up 6.6 ± 3.7 years.Mean age 47.4 14.9...
To review the experience of surgical repair post-infarction ventricular septal rupture (VSR) and analyze associated outcomes prognostic factors. Following approval from Singhealth Centralised Institutional Review Board (reference: 2011/881/C), a retrospective was performed on 38 consecutive patients who had undergone VSR between 1999 2011. Continuous variables were expressed as either mean ± standard deviation or median with 25th 75th percentiles. These compared using two-tailed t-test...
The aim of this study is to examine factors that can predict mortality in patients have veno-arterial extracorporeal membrane oxygenation (VA-ECMO) instituted for cardiogenic shock. A single-center, retrospective 127 who underwent VA-ECMO shock between January 2003 and December 2017 was conducted. Eighty-three (65%) survived weaning or bridging therapy. Complications on include: hemorrhage (40%), stroke (14%), requirement dialysis (42%), limb ischemia (24%). Univariate analysis revealed...
This study evaluates various wrist and thumb positions for tensioning the extensor indicis proprius when transferred to pollicis longus tendon determine which provide optimum passive range of flexion extension thumb. In five adult cadaver upper limbs, transfer was simulated. The limbs were fixed with elbow in 90 degrees forearm neutral. Surface bone markers digitized three-dimensional space their intersegmental joint angles. Twelve combinations (the interphalangeal metacarpophalangeal...
Background: The use of cerebral embolic protection devices during transcatheter aortic valve implantation (TAVI) reveals conflicting data.Aims: This updated meta-analysis aims to evaluate the efficacy and safety SENTINEL Cerebral Protection System.Methods: A literature search for relevant studies up September 2022 was performed.Study outcomes were divided based on time period -overall (up 30 days) short (≤7 days).The studied include stroke (disabling, non-disabling), mortality, neuroimaging...
Given the high risk of peri-operative morbidity and mortality associated with open repair, endovascular repair for thoraco-abdominal aneurysms is increasingly performed. This study aims to describe mid long-term results patients who were treated COOK Custom-Made Endograft Device at a single Southeast Asian tertiary centre.
A 21-year-old woman presented with almost complete extrinsic airway obstruction due to a massive mediastinal tumor. Venovenous extracorporeal membrane oxygenation support for 3 days concurrent chemotherapy allowed time tumor shrinkage, ventilation via the endotracheal route, and subsequent successful extubation on fifth day.
Purpose: To report a candy-plug technique using Zenith Alpha stent-graft to occlude the distal false lumen in patient with complicated chronic type B aortic dissection. Case Report: A 50-year-old male smoker presented chest pain due rapidly growing Computed tomography angiography (CTA) showed dissection extending from origin of left subclavian artery (LSA) down femoral artery. There was fusiform aneurysmal dilatation proximal descending aorta measuring up 5.8 cm diameter. He underwent...
Restrictive mitral annuloplasty is the mainstay of surgical correction chronic ischaemic regurgitation (CIMR). Long-term data on various types rings limited. The aim this study was to investigate clinical and echocardiographic outcomes restrictive in patients with CIMR, comparing use flexible versus semi-rigid rings.A retrospective review conducted for 133 CIMR who underwent at our institution between 1999 2015. Patient demographics postoperative were analyzed.Mean age 61.9±9.2 years 103...
Introduction: Chronic kidney disease (CKD) is a significant comorbidity in aortic stenosis (AS) patients. We examined the impact of baseline CKD, postoperative acute injury (AKI) and CKD progression on clinical outcomes patients who underwent transcatheter valve implantation (TAVI). Materials Methods: Consecutive with severe AS TAVI were classified into stages 1–2 (≥60 mL/min/1.72m2), 3 (30–59 mL/min/1.73m2) 4–5 (<30 mL/min/1.73m2 or dialysis) based estimated glomerular filtration rate...
Data on patients with small aortic annuli (SAA) undergoing transcatheter valve implantation (TAVI) are limited. We aim to describe the impact of annular size, particularly SAA and TAVI type haemodynamics, durability clinical outcomes.All in National Heart Centre Singapore who underwent transfemoral for severe symptomatic native stenosis from July 2012 December 2019 were included. Outcome measures include prosthesis-patient mismatch (PPM), structural degeneration (SVD) mortality.A total 244...