Neurons in the middle temporal visual area (MT) have been implicated perception of motion, whereas prefrontal cortex (PFC) neurons linked to temporary storage sensory signals, attentional and executive control behavior. Using a task that placed demands on both sets neurons, we investigated their contribution working memory for motion. Monkeys compared direction two moving random-dot stimuli, sample test, separated by brief delay. areas showed robust direction-selective activity during all...

Journal Article Motion Perception following Lesions of the Superior Temporal Sulcus in Monkey Get access Tatiana Pasternak, Pasternak 1Department Neurobiology and AnatomyRochester, New York 146423Department Center for Visual Science, University RochesterRochester, 14642 Correspondence should be addressed to Rochester, NY 14627 Search other works by this author on: Oxford Academic PubMed Google Scholar William H. Merigan 2Department OphthalmologyRochester, Cerebral Cortex, Volume 4, Issue 3,...

We recorded the activity of middle temporal (MT) neurons in 2 monkeys while they compared directions motion sequentially presented random-dot stimuli, sample and test, reported them as same or different by pressing one buttons. found that MT were active not only response to test stimuli but also during 1,500-ms delay separating them. Most showed a characteristic pattern consisting small burst firing early delay, followed period suppression subsequent increase rate immediately preceding...

During motion discrimination tasks, many prefrontal cortex (PFC) neurons are strongly modulated by the behavioral context, suggesting their involvement in sensory discriminations. Recent studies suggest that trial-to-trial variability of spiking activity characteristic cortical could be a source information about state and participation tasks. We tested this hypothesis examining putative pyramidal PFC neurons, likely top-down influences. The these was calculated as ratio spike count variance...

Comparing two stimuli that occur at different times demands the coordination of bottom-up and top-down processes. It has been hypothesized dorsolateral prefrontal (PFC) cortex, likely source cortical influences, plays a key role in such tasks, contributing to both maintenance sensory comparisons. We examined this hypothesis by recording from PFC monkeys comparing directions moving stimuli, S1 S2, separated memory delay. determined contribution principal cell types these processes classifying...

Neuronal activity in the lateral prefrontal cortex (LPFC) reflects structure and cognitive demands of memory-guided sensory discrimination tasks. However, we still do not know how neuronal articulates network states involved perceiving, remembering, comparing information during such Oscillations local field potentials (LFPs) provide fingerprints dynamics. Here, examined LFPs recorded from LPFC macaques while they compared directions or speeds two moving random-dot patterns, S1 S2, separated...

Neurons in the visual cortex of cats reared 8 Hz stroboscopic illumination show a profound loss directional selectivity, but no detectable deficits orientation contrast sensitivity, and temporal frequency response, only slight reduction spatial resolution. In present study, vision, resolution, variety motion detection discrimination thresholds were examined behaviorally such cats. These psychophysical measurements revealed nearly normal severe abnormalities discriminations based on...

When a monkey needs to decide whether motion direction of one stimulus is the same or different as that another held in working memory, neurons dorsolateral prefrontal cortex (DLPFC) faithfully represent directions being evaluated and contribute their comparison. Here, we examined DLPFC are more generally involved other types sensory comparisons. Such involvement would support existence generalized comparison mechanisms within DLPFC, shedding light on top-down influences this region likely...

We applied electrical stimulation to physiologically identified sites in macaque middle temporal area (MT) examine its role short-term storage of recently encoded information about stimulus motion. used a behavioral task which monkeys compared the directions two moving random-dot stimuli, sample and test, separated by 1.5-s delay. Four were for each site, animals had indicate whether direction motion was same as or different test. found that effect directional column MT depended on state...

When asked to compare two moving stimuli separated by a delay, observers must not only identify stimulus direction but also store it in memory. We examined the properties of this storage mechanism macaque monkeys sequentially presenting random-dot stimuli, sample and test, opposite hemifields introducing random-motion mask during delay. The interfered with performance at precise location 100–200 ms after start when its size speed matched those remembered sample. This selective interference...

Abstract We examined the role of lateral suprasylvian (LS) cortex in motion perception by testing ability three cats to detect moving targets and discriminate differences stimulus direction speed before after making bilateral ibotenic acid lesions LS. The had little or no effect on contrast sensitivity for detecting sinusoidal gratings. Moreover, we found deficits discriminating opposite directions motion: discriminated grating at threshold contrasts. All cats, however, showed permanent...

Visually guided behavior often involves decisions that are based on evaluating stimuli in the context of those observed previously. Such made by monkeys comparing two consecutive stimuli, sample and test, moving same or opposite directions. We examined whether responses motion processing area MT during comparison phase this task (test) modulated direction preceding stimulus (sample). This modulation, termed signal, was measured to identical test trials when it preceded (S-trials) with a...

We asked if the information about stimulus motion used in a visual working-memory task is localized space. Monkeys compared directions of two moving random-dot stimuli, sample and test, separated by temporal delay reported whether stimuli moved same or different directions. By presenting comparison separate locations field, we determined direction was spatially during storage retrieval/comparison components task. Two psychophysical measures discrimination provided nearly identical estimates...

We examined the effects of bilateral ibotenic acid lesions cat lateral suprasylvian (LS) cortex on motion perception. Cats were tested tasks requiring integration local directional signals, precise judgements direction and extraction structure-from-motion. All animals showed permanent deficits in integrating signals. These most pronounced presence noise at larger spatial displacements. In addition, LS produced a 2-fold loss accuracy discrimination large perception these losses severe during...

The contribution of the lateral prefrontal cortex (LPFC) to working memory is topic active debate. On one hand, it has been argued that persistent delay activity in LPFC recorded during some tasks a reflection sensory storage, notion supported by lesion studies. other there emerging evidence plays key role maintenance information not storing relevant visual signals but allocating attention such stimuli. In this study, we addressed question examining effects unilateral lesions task requiring...

Visual intensity difference thresholds were studied before and after telencephalic lesions in pigeons. Subjects with visual Wulst showed initial postoperative threshold elevations that represented losses of 19%-49% their preoperative sensory capacity. This loss was correlated the extent damage to three components Wulst: nucleus intercalatus hyperstriati accessorii, hyperstriatum suprema, accessorium. The dorsale, another component Wulst, made no contribution deficit. capacity all but one...