A5050792131- Cardiovascular and exercise physiology
- Sports Performance and Training
- Sports injuries and prevention
- Cardiovascular Health and Disease Prevention
- Adipose Tissue and Metabolism
- High Altitude and Hypoxia
- Heart Rate Variability and Autonomic Control
- Muscle activation and electromyography studies
- Cardiovascular Effects of Exercise
- Thermoregulation and physiological responses
- Stroke Rehabilitation and Recovery
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Children's Physical and Motor Development
- Delphi Technique in Research
- Autophagy in Disease and Therapy
- Muscle metabolism and nutrition
- Schizophrenia research and treatment
- Mitochondrial Function and Pathology
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Behavioral Health and Interventions
- Sirtuins and Resveratrol in Medicine
- Spaceflight effects on biology
- Physical Activity and Health
- Musculoskeletal pain and rehabilitation
Queen's University
2018-2025
University of Ottawa
2021-2025
Abstract Objectives Aerobic exercise training can increase skeletal muscle mitochondrial content. Supine with legs above the heart potentially augments these increases. However, impact of supine on biogenesis and cardiovascular adaptations remains unclear. Methods In this single-centred, randomized, parallel arm trial, 19 recreationally active individuals underwent seven sessions either up (SUP; n=9, 6 females) or upright down (UP; n=10, 7 aerobic a recumbent bike at 71 ± % 2 peak work rate...
We examined maximal oxygen consumption responses following exercise training to demonstrate the limitations associated with threshold-based dichotomous classification of responders and non-responders proposed alternative methods for classification. Specifically, we: 1) calculated individual probabilities response, 2) classified individuals using response confidence intervals (CI) reference points zero a smallest worthwhile change 0.5 METs. Our findings support use CIs improve accuracy in non-response
This study tested the hypothesis that a novel, gravity-induced blood flow restricted (BFR) aerobic exercise (AE) model will result in greater activation of AMPK-PGC-1α pathway compared with work rate-matched non-BFR. Thirteen healthy males (age: 22.4 ± 3.0 years; peak oxygen uptake: 42.4 7.3 mL/(kg·min)) completed two 30-min bouts cycling performed their legs below (CTL) and above heart at ∼2 weeks apart. Muscle biopsies were taken before, immediately, 3 h after exercise. Blood was drawn...
The purpose of this study was to test the hypotheses (i) that interindividual variability in acute blood lactate responses during exercise at 65% peak work rate (WR ; relative WR protocol (REL)) will predict chronic training and (ii) exercising an intensity causes uncomfortable speech production (negative talk (TT) stage (NEG)) elicits high large adaptations training. Twenty-eight participants completed 4 weeks consisting REL (n = 14) or NEG (TT, n 14). Fifteen additional were assigned a...
Young adults (52 females, 16 males; age = 21 ± 3 years; V̇O 2peak : 41 6 mL/(kg·min)) were randomized into groups: (i) no-exercise control (CTL; n 15), (ii) Tabata (n 27), or (iii) vigorous-intensity continuous training (VICT; 26) groups for a 4-week supervised period (4 sessions/week). , time-to-fatigue (TTF), 5 km time-trial performance (TT), and muscular endurance assessed at baseline, post-training (POST), 2-month follow-up (FU). Response confidence intervals (CI) used to classify...
What is the central question of study? Do interindividual differences in trainability exist for morphological and molecular skeletal muscle responses to aerobic exercise training? main finding its importance? Interindividual were present some, but not all, outcomes included our study. Our findings suggest that it inappropriate, perhaps erroneous, assume variability observed reflects training.Studies have interpreted a wide range changes human as evidence trainability. However, these...
This study tested the hypotheses that 1) skeletal muscle biopsies performed with Bergström needle evoke larger perceptions of pain and greater hemodynamic reactivity compared to microbiopsy needle, 2) both needles yield samples similar fibre type compositions when are collected at depths. Fourteen healthy (age: 21.6 ± 3.2 years; VO2peak: 41.5 5.8 mL/kg/min) males (n = 7) females provided two resting biopsies, one each type, following a randomized crossover design. Participants completed...
We tested the hypothesis that AMPK activation and peroxisome proliferator gamma coactivator 1 alpha (PGC-1
Many reports describe using a supramaximal verification phase—exercising at power output higher than the highest recorded during an incremental cardiopulmonary test—to validate VO 2max . The impact of phases on estimating proportion individuals who increased 2peak in response to high-intensity interval training (HIIT) remains underexplored area individual literature. This analysis investigated influence same-day and separate-day repeated measurements (incremental tests—INCR1 INCR2; tests +...
Introduction: Acute exposure to increases in oscillatory shear stress (increased retrograde and decreased mean stress) reduces flow-mediated dilation (FMD). This impairment may be mediated via increased oxidative stress. Habitual endurance exercise training results antioxidant protection. However, it is currently unknown whether these adaptations protect against stress-induced impairments FMD. Purpose Hypothesis: The purpose of this study determine lower limb endurance-trained athletes have...
Introduction: Acute exposure to increases in oscillatory shear stress (increased retrograde and decreased mean stress) reduces flow-mediated dilation (FMD). This impairment may be mediated via increased oxidative stress. Habitual endurance exercise training results antioxidant protection. However, it is currently unknown whether these adaptations protect against stress-induced impairments FMD.
 Purpose Hypothesis: The purpose of this study determine lower limb endurance-trained athletes...