- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- COVID-19 Clinical Research Studies
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Streptococcal Infections and Treatments
- Cardiac pacing and defibrillation studies
- Heart Rate Variability and Autonomic Control
- ECG Monitoring and Analysis
- Pericarditis and Cardiac Tamponade
- Cardiovascular Disease and Adiposity
- COVID-19 and healthcare impacts
- Inflammasome and immune disorders
- Central Venous Catheters and Hemodialysis
- Non-Invasive Vital Sign Monitoring
- Lipoproteins and Cardiovascular Health
- Long-Term Effects of COVID-19
Post Graduate Institute of Medical Education and Research
2015-2025
Lingaya's Vidyapeeth
2024
Rutgers, The State University of New Jersey
2024
Vivekananda Institute of Medical Sciences
2024
Indira Gandhi Medical College
2023
University of Virginia
2023
Government Medical College
2023
University of California, Irvine
2022
Command Hospital Air Force
2021
IQVIA (India)
2020
Coronavirus disease 2019 (COVID-19) pandemic unmasked the huge deficit in healthcare resources worldwide. It highlighted need for efficient risk stratification management of cardiovascular emergencies.To study applicability old, available and affordable nonconventional biomarkers: albumin fibrinogen their ability to predict angiographic severity clinical outcomes patients with acute coronary syndrome (ACS).In this prospective, observational study, 166 consecutive ACS were enrolled....
Background. Potentially lethal cardiac complications can occur in patients with acute organophosphate poisoning (OPP) and may be overlooked. Patients Methods. Thirty-six OPP were studied. Clinical features the nature of compound involved recorded. The QT interval was plotted against heart rate to determine risk for Torsades de Pointes using Fossa nomogram. Echocardiography undertaken 29 patients. Twenty-four-hour Holter monitoring performed on day 1 five Thirteen died. Necropsy hearts...
The relationship of atrial fibrillation (AF) with coronary artery disease (CAD) is well established, yet it often missed. There evidence myocardial ischemia on stress imaging in AF patients the absence obstructive CAD. In this prospective cohort, we studied angiographic profiles non-valvular patients.The study was a nonrandomized, prospective, single-center observational consecutive persistent AF. Patients symptomatic for despite optimal medical therapy 3 months were recruited and all...
Several studies have demonstrated a shift in the spectrum of infective endocarditis (IE) developed world. We aimed to investigate whether demographic and microbiologic characteristics IE changed India.A retrospective analysis patients with north India between 2010 2020.The clinical laboratory profiles 199 admitted an academic hospital who met modified Duke criteria for definite were analysed.The mean age was 34 years, 84% males. The main predisposing conditions injection drug use (IDU) (n =...
Cardiovascular disease is the leading cause of death in India. Our aim to study clinical, epidemiological profile and in-hospital outcomes patients presenting with acute coronary syndrome.We did a prospective single center observational 1203 ACS tertiary referral North India over period one year (July 2018-June 2019).The mean age population was 58.4 ± 12.5 years. STEMI NSTE-ACS accounted for 69.9% 31.1% respectively. 62.1% our were from rural background. The median time hospital admission...
Coronary artery disease (CAD) is a highly considered dangerous which may lead to myocardial infarction and even sudden cardiac death. The objective of this work evaluate the diagnostic performance features derived from linear non-linear methods Heart Rate Variability (HRV) analysis for classification software modules with Normal (NOR) subjects CAD patients. proposed methodology follows recording electrocardiogram 60 NOR 64 patients, RR interval tachogram generation, computing time domain,...
Coronary Artery Disease (CAD) is a major global health problem. Recent studies demonstrated that lower vitamin D level (<30ng/ml) associated with higher blood pressure and directly or indirectly CAD, due to vascular endothelial damage. However the results are inconsistent.To find association of deficiency CAD.In this cross-sectional observational study, serum was measured in 315 patients who underwent coronary angiography.The mean (±SD) 13.40ng/ml (±10.40). However, normal artery had much...
Common single-nucleotide polymorphisms (SNPs) in genes of lipid metabolism modestly influence plasma low-density lipoprotein cholesterol (LDL-C) and risk coronary artery disease (CAD). We evaluated a panel LDL-C–modulating SNPs for potential association with CAD Asian Indians. Fifteen CETP, ABCB1, APOAI, CYP7A1, HMGCR were genotyped 265 patients 150 controls North Indian origin. A proatherogenic genotype score was formulated based on number alleles associated LDL-C CAD. observed 12 from to...
Delayed presentation after ST-elevation myocardial infarction (STEMI) and complicated by cardiogenic shock (CS-STEMI) is commonly encountered in developing countries a challenging scenario because of delay revascularization resulting large amount the myocardium. We aimed to assess clinical characteristics, angiographic profile, predictors outcome patients with delayed CS-STEMI. A total 147 CS-STEMI time appropriate medical care ≥12 h symptom onset were prospectively recruited at tertiary...
The aim of this study is to analyse and compare the heart rate variability (HRV) normal hypertension cases using time domain, frequency nonlinear methods. For short term HRV analysis, a five-minute electrocardiogram (ECG) 57 56 subjects were recorded with prior verification their clinical status by cardiologist. Most domain features have clearly reduced values over subjects, features, like power in different spectral bands, also distinguishable decreased values, whereas sympathovagal balance...
To compare the efficacy, safety, cost and effects on platelet aggregation of unfractionated heparin low-molecular weight in unstable angina patients.Ninety-three patients with were randomized to receive either (UFH) or enoxaparin an open design clinical trial blinded end point evaluation. The heparins also compared.The composite myocardial infarction, cardiac death, recurrent need for intervention was observed 62% treated UFH 37% (RR 1.7, 95% CI 0.75 3.71, p = 0.04). There no difference...
Context: Acute rheumatic fever (ARF)/rheumatic heart disease (RHD) is a major cause of morbidity and mortality in India, yet, few studies are available on susceptibility markers.Objective: To associate human leukocyte antigen (HLA) class II alleles with north Indian RHD patients as genetic markers.Materials methods: HLA were analysed using sequence specific primer-polymerase chain reaction nucleotide sequencing, while HLA-B27 expression by flowcytometry.Results: Few HLA-DQB1/DRB1 associated...